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Bioinformatic and algorithmical studies

This section considers studies on the development and application of novel computational and statistical methods to the analysis of genomic data for the study of health and disease.

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1.

Research article   Open Access

Identification and characterization of alternative exon usage linked glioblastoma multiforme survival

Ahmed Sadeque, Nicola VL Serão, Bruce R Southey, Kristin R Delfino, Sandra L Rodriguez-Zas BMC Medical Genomics 2012, 5:59 (4 December 2012)

Abstract | Full text | PDF | PubMed

2.

Research article   Open Access

Visualization and identification of health space, based on personalized molecular phenotype and treatment response to relevant underlying biological processes

Jildau Bouwman, Jack TWE Vogels, Suzan Wopereis, Carina M Rubingh, Sabina Bijlsma, Ben van Ommen BMC Medical Genomics 2012, 5:1 (6 January 2012)

Abstract | Full text | PDF | PubMed

3.

Research article   Open Access Highly Accessed

Batch effect correction for genome-wide methylation data with Illumina Infinium platform

Zhifu Sun, High Chai, Yanhong Wu, Wendy M White, Krishna V Donkena, Christopher J Klein, Vesna D Garovic, Terry M Therneau, Jean-Pierre A Kocher BMC Medical Genomics 2011, 4:84 (16 December 2011)

Abstract | Full text | PDF | PubMed

4.

Research article   Open Access

Estimates of array and pool-construction variance for planning efficient DNA-pooling genome wide association studies

Madalene A Earp, Maziar Rahmani, Kevin Chew, Angela Brooks-Wilson BMC Medical Genomics 2011, 4:81 (28 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

5.

Research article   Open Access

Quantifying stability in gene list ranking across microarray derived clinical biomarkers

Sebastian Schneckener, Nilou S Arden, Andreas Schuppert BMC Medical Genomics 2011, 4:73 (14 October 2011)

Abstract | Full text | PDF | PubMed

6.

Research article   Open Access

Bayesian probit regression model for the diagnosis of pulmonary fibrosis: proof-of-principle

Eric B Meltzer, William T Barry, Thomas A D'Amico, Robert D Davis, Shu S Lin, Mark W Onaitis, Lake D Morrison, Thomas A Sporn, Mark P Steele, Paul W Noble BMC Medical Genomics 2011, 4:70 (5 October 2011)

Abstract | Full text | PDF | PubMed

7.

Research article   Open Access Highly Accessed

Integrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma

Siyuan Zheng, William P Tansey, Scott W Hiebert, Zhongming Zhao BMC Medical Genomics 2011, 4:62 (8 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

Research article   Open Access

A computational procedure for functional characterization of potential marker genes from molecular data: Alzheimer's as a case study

Margherita Squillario, Annalisa Barla BMC Medical Genomics 2011, 4:55 (5 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

9.

Research article   Open Access Highly Accessed

The functional cancer map: A systems-level synopsis of genetic deregulation in cancer

Markus Krupp, Thorsten Maass, Jens U Marquardt, Frank Staib, Tobias Bauer, Rainer König, Stefan Biesterfeld, Peter R Galle, Achim Tresch, Andreas Teufel BMC Medical Genomics 2011, 4:53 (30 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

Research article   Open Access Highly Accessed

Multiplicity: an organizing principle for cancers and somatic mutations

Lewis J Frey, Stephen R Piccolo, Mary E Edgerton BMC Medical Genomics 2011, 4:52 (29 June 2011)

Abstract | Full text | PDF | PubMed

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