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Using massive parallel sequencing of DNA from dogs and wolves, the authors have found 155 new genetic variants of canine Toll-like receptors, primary sensors of pathogens in the body.
In this forum article, experts discuss non-communicable diseases (NCDs) that, despite causing significant health issues, do not receive the attention they deserve, highlighting the need for higher global health priority to reduce the burden of disease.
Explaining why ethics and informed consent processes for genomic studies need to be more transparent in the case of vulnerable African populations.
Epigenetic modifications such as histone and DNA methylation are essential for silencing pluripotency genes. A critical step is identified for the self-renewal and differentiation of embryonic stem cells.
Oral phenobarbital and imepitoin are amongst likely effective anti-epileptic drugs for the treatment of canine idiopathic epilepsy (IE); however, poor reporting in literature preclude definitive recommendations prompting a need for greater blinded RCTs evaluating the efficacy of these drugs.
Low alcohol consumption without heavy drinking reduces ischemic heart disease (IHD) risk, but episodic and heavy drinking have no beneficial effect, suggesting that average alcohol consumption measures are not sufficient to predict IHD risk.
COPD symptoms are more common in the early morning and day versus the night and over half of the 727 patients studied experienced symptoms during a 24 hour period. These outcomes should be considered when managing the disease.
Despite the known harms of excessive alcohol consumption, it is considered an acceptable risk; Jürgen Rehm et al. explore this issue, finding that alcohol’s special status may be due to overestimation of its health benefits when consumed in moderation.
Alan Lopez, a global health expert and epidemiologist, answers our questions about global burden of tobacco-related mortality, highlighting ways in which countries could apply tobacco control measures to alleviate this burden.
In this video Q&A, we interview Sir Ian Gilmore on the global burden of alcohol in terms of its scale and consequences relating to illness, and discuss the strategies that are addressing the problem.
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Latest article collections and supplements
Collection published: 22 October 2014
Big Risks - the challenges and opportunities in addressing the biggest global causes of premature mortality
Collection published: 21 October 2014
Updated: 22 October 2014
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Collection published: 20 October 2014
Edited by: Prof Jorge Alio
Collection published: 16 October 2014
Collection published: 14 October 2014
Updated: 21 October 2014
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BioMed Central news
Safety in Health is accepting submissions
The journal encompasses global trends in healthcare affecting quality and safety. This includes patient safety, training and simulation, health economics, quality and process management, as well as critical incidents including the legal or regulatory aspects.
For those wishing to submit a manuscript, click on the link for the instructions for authors and information about the journal's policies.
Eye and Vision has fully launched
We are delighted to announce that Eye and Vision has now fully launched with BioMed Central and published its first articles.
Eye and Vision, supported by Wenzhou Medical University, is an interdisciplinary journal which covers both ophthalmology and optometry. It aims to keep the ophthalmologists and visual science specialists up-to-date with the latest development in theoretical, experimental and clinical investigations in eye and vision. In doing so, it will promote the exchange of innovative ideas and advanced information worldwide.
For more information please take a look at the launch editorial by Editor-in-Chief, Prof. Jia Qu.
Fungal Biology and Biotechnology has launched
We are pleased to announce that Fungal Biology and Biotechnology (FBB) has launched.
FBB is our first dedicated fungal journal. It publishes articles on all aspects of fungal research from basic biology to applied science. Read the launch Editorial by the two Editors-in-Chief, Alexander Idnurm and Vera Meyer, a fantastic Review from Claudio Scazzocchio and the first published research articles.
Follow the social media campaign #fungalfortnight.
Gynecologic Oncology Research and Practice has now launched
We are pleased to announce that Gynecologic Oncology Research and Practice has published its first articles with BioMed Central.
Edited by Robert L Coleman, Thomas J Herzog, and Bradley J Monk, Gynecologic Oncology Research and Practice is a new journal that publishes articles on the pathophysiology, prevention, diagnosis, and treatment of all cancers of the female reproductive system.