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Previous research suggested a need for increased prescribing of generic risperidone in Western Europe; Michael Berk and colleagues argue for a balance between cheapest drug use and optimal tailored care to ensure beneficial patient outcomes.
Although phenotypically identical, pericardial adipose tissue-derived stromal cells (ADSCs) in comparison to subcutaneous ADSCs were shown to exhibit potent differentiation towards cardiomyocytes and induced significant structural repair in the injured heart.
Epinephrine may be injected into the bone of anaphylactic children weighing under 15kg, implying that further research is needed to determine the appropriate needle length for pediatric patients.
Active vaccine AADvac1 validates the novel tau target revealed by monoclonal antibody DC8E8 by reducing Alzheimer's disease-type tau hyperphosphorylation by 95% in transgenic rats, and has now entered phase I clinical trials.
Monoclonal antibody DC8E8 disables a novel target on tau protein essential for its pathological function both in vitro and in vivo, and is a suitable candidate molecule for Alzheimer's disease immunotherapy.
Female mocker swallowtail butterflies show a remarkable variety of wing patterns, each mimicking a different poisonous butterfly species; a new study provides insights into the evolution of the supergene locus that makes these polymorphisms possible.
It is a challenge to assess whether rare and patient-specific mutations are cancer drivers. The algorithm DawnRank prioritizes altered genes on a single patient level.
In a randomized trial, a community-based intervention aiming to prevent intimate partner violence (IPV) and HIV-risk behaviors in Uganda successfully reduced acceptance and incidence of IPV, and is now being delivered in other communities.
A self-reported lack of physical activity was associated with shortened telomere length in early stage breast cancer survivors, suggesting a mechanism by which exercise can reduce cellular aging.
Jigisha Patel suggests current flaws within peer review systems in medical journals can be tackled by defining aims of peer review, offering training and recognition for reviewers, and providing readers with a way of identifying individual published articles that have been assessed by ‘trained’ reviewers.
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Latest article collections and supplements
Integrated Community-Based Interventions for the Prevention and Control of Infectious Diseases of Poverty
Edited by: Dr Johannes Sommerfeld, Prof Xiao-Nong Zhou
Collection published: 31 July 2014
Updated: 1 August 2014
Edited by: Prof Flora Tassone, Prof Randi Hagerman, Prof Paul Hagerman
Collection published: 30 July 2014
Edited by: Ms Amaia Bacigalupe, Dr Miguel San Sebastian, Dr Antonio Escolar Pujolar
Collection published: 25 July 2014
Edited by: Dr Carrie Shawber, Prof Jan Kitajewski, Dr Michael Simons
Collection published: 23 July 2014
Collection published: 21 July 2014
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Journal of Biological Research-Thessaloniki has now launched
We are pleased to announce that the Journal of Biological Research-Thessaloniki has now fully launched and has published its first articles. It is an international journal that publishes articles providing novel insights into the major fields of biology. Topics covered include molecular biology, cytology, genetics, evolutionary biology, morphology, development & differentiation, taxonomy, bioinformatics, physiology, marine biology, behaviour, ecology and conservation.
Military Medical Research has now launched
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We are delighted to announce that Pilot and Feasibility Studies is now open for submissions. The journal publishes research articles that are intended to directly influence future clinical trials, as well as protocols, commentaries and methodology articles. The journal also ensures that the results of all well-conducted, peer-reviewed, pilot and feasibility studies are published, regardless of outcome or significance of findings.