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  • Prognostic perturbation signature

    Denoising perturbation signatures reveals an actionable AKT-signaling gene module underlying a poor clinical outcome in endocrine treated ER+ breast cancer

    Genome Biology 2015, 16:61
  • Image attributed to: (Wikimedia commons BruceBlaus)

    Mitochondria, metabolism & disease

    Mitochondrial dysfunction and impairments in oxidative metabolism occur in neuroimmune and neuropsychiatric disorders; Michael Berk and Gerwyn Morris discuss the mechanisms underlying these processes, which could contribute to disease pathogenesis.

    BMC Medicine 2015, 13:68
  • Human genomic history

    Pugach and Stoneking provide genome-wide insights into the genetic history of human populations in Southern Africa, India, Oceania, Island South East Asia and the Americas.

    Investigative Genetics 2015, 6:6
  • Inferring positive selection in humans from genomic data

    Wollstein and Stephan discuss the two competing models of adaptation and suitable approaches for detecting the footprints of positive selection on humans at the molecular level.

    Investigative Genetics 2015, 6:5
  • Colon cancer 5hmC

    Promoters 5-hydroxymethylated during normal colon differentiation are resistant to neoplastic hypermethylation

    Genome Biology 2015, 16:69
  • Laryngeal tuberculosis diagnosed by stool sample cultures

    With current methods, laryngeal tuberculosis is commonly misdiagnosed. Evidence suggests that stool cultures could be used in the diagnosis of atypical forms of tuberculosis; this is the first case report to describe the successful use of stool cultures in tuberculosis diagnosis.

    Journal of Medical Case Reports 2015, 9:74
  • Image attributed to: Flickr (CC, Ed Uthman)

    Artemisinin resistance genetics

    Carol Sibley discusses recent findings on the genetic changes associated with artemisinin resistance in P. falciparum parasites, highlighting the importance of understanding the evolution of resistance to maintain antimalarial effectiveness.

    BMC Medicine 2015, 13:67
  • Image attributed to: istock photo

    Fixed dosed AS-AQ optimal for malaria

    In a meta-analysis of artesunate-amodiaquine (AS-AQ) treatment for malaria, there is variation in the AQ dose administered under different regimens and fixed dose combinations provide high efficacy, highlighting the importance of correct dosing in malaria treatment.

    BMC Medicine 2015, 13:66
  • Image attributed to: Flickr:  Michael Dorausch

    Youth accessing e-cigarettes for experimentation

    E-cigarettes are being accessed by teenagers more for experimentation than smoking cessation and mostly by those who engage in other substance-related risk behaviours including regular smoking, binge drinking and alcohol-related violence.

    BMC Public Health 2015, 15:244
  • Image attributed to: Prostate cancer cells from an organoid, produced by NIH

    Organoid cancer models

    Michael Cantrell and Cavlin Kuo discuss recent developments in the three-dimensional culture of organoids and their promise for both bottom-up and top-down screening to find cancer drivers.

    Genome Medicine 2015, 7:32
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    Journal of Congenital Cardiology is now accepting submissions

    The journal is dedicated to the advancement of research and understanding in fetal, pediatric and adult congenital heart disease. It is led by Editor-in-Chief Graham Stuart (Bristol Royal Hospital, UK) and is supported by an expert Editorial Board which will continue to expand.


    Click here if you're doing research in genetics, epidemiology, electrophysiology and interventions and wish to submit your article.

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    Chinese Journal of Cancer has now fully launched

    Browse through the first papers published covering basic, clinical, and translational cancer research.

    The expert Editorial Board is led by Editor-in-Chief Prof. Yi-Xin Zeng from Peking Union Medical College, and the journal is sponsored by Sun Yat-sen University Cancer Center. So authors do not need to pay an article-processing charge.

    It welcomes all submissions concerning clinical trials, epidemiology, molecular and cellular biology and genetics in all aspects of cancer research.

     

     

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    Journal of Pharmaceutical Health Care and Sciences (JPHCS) has now fully launched.

    It is the official English journal of the Japanese Society of Pharmaceutical Health Care and Sciences, publishing research in all aspects of pharmaceutical health care and sciences, including clinical pharmacy and clinical and experimental pharmacotherapy. 

    "The aim of the journal is to offer an open access forum for the publication of scientifically rigorous articles focusing on all fields of pharmaceutical health care and sciences," explains Editor-in-Chief, Professor Toshiya Katsura in his editorial. Click the link to find out more and read the review on pharmacist-managed clinics.

     

     

     

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    Disaster and Military Medicine has fully launched.

    This is the first journal to encompass all aspects of disaster and military medicine as well as pre-hospital, trauma and emergency care. The Editor in Chief, Dr. Eyal Zimlichman of Chaim Sheba Medical Center in Israel, is an expert in health care quality, patient safety and health information technology. In his blog 'Building the bridge', Dr. Zimlichman's discusses the necessity for such a journal.

    In 2015, the journal is planning two thematic issues, one focused on Disaster Response in Japan and another on Primary Care in Combat Zones.

     

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