Journal of Experimental & Clinical Cancer Research 2010, 29:120
Predictive gene signatures allow us to evaluate risk in different breast tumours, and this novel algorithm has been designed to accurately identify shorter gene signatures that can be used to predict the prognosis of a person suffering with breast cancer.
The natural herbal compound Penta-O-galloyl--D-glucose induced breast cancer cell apoptosis in cell lines and is orally active against triple negative xenograft growth in mice.
How many different clocks govern the rate of evolution? Alexei Drummond and Marc Suchard address this question with Bayesian modeling of local clocks that tick at different rates in different parts of the phylogenetic tree.
Placental mammals are insensitive to the feminizing effects of oestrogen during development, but marsupials, like other vertebrate species, are susceptible. Commenting on a paper in BMC Biology, Mork and Capel discuss what is known of the mechanism of oestrogen sensitivity.
Oestrogen can overcome the influence of the SRY testis-determining gene in marsupials. Renfree and colleagues report that it acts by preventing the crucial transcription factor Sox9 from shuttling into the nucleus.
Appreciation for review
(Ray Greek, 02Sep2010)
We thank Dr Wolpert for taking his time and applying his considerable intellect to review our book Animal Models in Light of Evolution. We are honored that Dr Wolpert reviewed...
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Wolpert L et al.Philosophy, Ethics, and Humanities in Medicine, 5:12
MatScan video available at JFAR YouTube Channel
(Hylton Menz, 02Sep2010)
A video showing the output of the MatScan system used in this study has been linked to the JFAR YouTube Channel: http://www.youtube.com/JFootAnkleRes#p/f/0/QuaEdhgLdKM The...
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Zammit GV et al.Journal of Foot and Ankle Research, 3:11
Keep up the good work
(brett davis best, 01Sep2010)
I would like to say that in my opinion also my hands on experience that Harm reduction is by far the greatest positive factor for the decrease of Hiv/Hep-c in the downtown...
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