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Specific types of monocytes ingest opsonized malaria erythrocytes and stimulate inflammation, indicating that these cells have a special role in activating the immune system against P. falciparum infection, which should be considered in vaccine design.
An intervention combining text message communication and reimbursement of clinic transportation costs reduces the time to clinic return and antiretroviral therapy commencement in rural Uganda, so could be a promising strategy to improve HIV care.
Crucial to the spread of the octopus from tropics to poles is their ability to sustain oxygen supply even at sub-zero temperatures; molecular and structural evolution of the octopus blood-carrying molecule appears to be key to this.
Cells sense and respond to physical forces in a broad range of biological phenomena. We invited leading researchers to discuss how the field of mechanotransduction is changing the way we think cells (and animals!) interact with their environments, and highlight striking examples from across different fields.
An adjustable fetal weight standard for twin pregnancies can be used to accurately assess growth while taking into account variables such as race, suggesting that this tool can be used in different populations.
In a Q-sort survey, tasks considered most important for peer reviewers of randomized controlled trials, were often not clearly indicated by editors, including evaluating the risk of bias, which was clearly requested by only 5% of journal editors.
The fern family of plants is extremely diverse; as well as being of intrinsic scientific interest it also includes species with significant commercial and industrial potential. Stable genetic transformation is a key research tool for any plant species and the lack of a reliable technique has previously hindered progress in exploring this important plant lineage. This paper describes a detailed step-by-step protocol for the efficient transformation of the model fern species, C. richardii, which should provide new and exciting opportunities for fern researchers.
Study design and algorithms developed to select participants with greatest potential for actionable variants and variants with highest impact to be incorporated in the EHR in the context of eMERGE.
Randomized trials are not always the best way to ascertain the benefit of medical interventions; Milo Puhan and colleagues argue that quantitative benefit-herm assessments should be used to guide further research, discussing rofilumast as an example.
This study demonstrates that the relationship between appearance comparison and body image dissatisfaction is comparative for those exposed to Facebook images and those exposed to conventional media images, thus endorsing the importance of extending the body image dissatisfaction literature by taking into account emerging social media formats.
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Big Data Analytics is now accepting submissions.
The journal aims to publish cutting-edge articles describing original basic and applied work involving biologically-inspired computational accounts of all aspects of big data science analytics.
The journal invites high-quality original research articles and timely reviews on current developments in the field, covering all aspects of big data analytics. Visit the journal website to find out why you should publish your article in Big Data Analytics.
Research Involvement and Engagement has published its first articles.
The new co-produced journal is both innovative and interdisciplinary. It is a health and social care journal that focuses on patient and wider involvement and engagement in research, at all stages.
All articles within the journal will be reviewed by both academics and patients, with both reports carrying equal weight in the editorial decision. The journal is led by two Editors-in-Chief –Sophie Staniszewska, PPI lead at RCN Research Institute, University of Warwick, UK, and Richard Stephens, an involved and engaged patient from the UK.
Read a fantastic piece on patient’s and clinicians’ priorities for research by Iain Chalmers and Sally Crowe.
Hereditas is now accepting submissions.
The journal was founded in 1920, hence it is one of the oldest journals in the field. It is the official publication of The Mendelian Society of Lund and transferred to BioMed Central this year.
Genes and Environment has published its first articles.