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    Prognosis and clinical practice

    Peter Croft et al. argue that decision making in clinical practice should be based on patient prognosis as well as disease diagnosis, highlighting that this prognostic model may improve future patient outcome by incorporating more information.  

    BMC Medicine 2015, 13:20
  • Image attributed to: Wikipedia CC Computerhotline

    Random factors act on P. falciparum infection

    In a mathematical model, the timing of infection by Plasmodium falciparum malaria mostly depends on random factors, suggesting that parasite growth rate could be more useful than time-to-infection measures in estimating protective immunity.

    BMC Medicine 2015, 13:19
  • Neuropsychiatric symptoms in Alzheimer’s dementia

    Lyketsos and colleagues review the current literature on the phenomenology and diagnosis, neurobiology, and treatment approaches for several key behavioral phenotypes in Alzheimer’s disease.

    Alzheimer's Research & Therapy 2015, 7:12
  • What can we learn from animal models?

    As part of the cerebral multi-morbidity series, Baker and Götz review the contribution that transgenic animal models have made to a better mechanistic understanding of the causes and consequences of co- or multi-morbidity.

    Alzheimer's Research & Therapy 2015, 7:11
  • Image attributed to: Flickr; suparna sinha

    Fetal liver affected by exposure to cigarettes

    Exposure to cigarette smoke leads to sex-specific epigenetic changes and disruption to key metabolic pathways in human fetal liver tissue (from 11-21 weeks of gestation), highlighting the impact of maternal smoking in early pregnancy.

    BMC Medicine 2015, 13:18
  • miRNAs in DLBCL

    miRNA sequencing in diffuse large B-cell lymphoma reveals many novel miRNAs, as well as some that are associated with survival

    Genome Biology 2015, 16:18
  • Image attributed to: From Fig 2 Valencia and colleagues

    CLL and gene expression variability

    A relationship between disease subtype in chronic lymphocytic leukemia and variation in gene expression suggests that variability has an effect on tumor adaptability and aggressiveness.

    Genome Medicine 2015, 7:8
  • Image attributed to: Detail of Figure 2 from Malhotra et al.

    Ploidy-Seq: a tool to reconstruct tumor evolution

    A novel method combining flow-sorting to separate tumor populations by ploidy with high-throughput sequencing shows promise to trace genome evolution in human cancer.

    Genome Medicine 2015, 7:6
  • Image attributed to: From Fig 1 Ruklisa et al.

    APPRAISE variant pathogenicity

    Disease-specific Bayesian models provide a robust, accurate and transparent framework to integrate multiple sources of evidence for the interpretation of novel variants from gene sequencing.

    Genome Medicine 2015, 7:5
  • Image attributed to: Flickr CC European Commission DG ECHO

    Nutrition supplement improves CD4 count

    A lipid-based nutritional supplement (LNS) with added micronutrients does not decrease mortality in malnourished HIV-infected adults compared with LNS alone, but improves the CD4 count, suggesting this intervention may provide clinical benefits.

    BMC Medicine 2015, 13:17
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Xiaolin Zhang on Open Access in China

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BioMed Central news

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    BMC Nutrition has officially launched

    'The voice of nutrition within the BMC-series', the journal considers articles on all aspects of nutritional sciences, including global interventions, clinical nutrition, and dietary supplementation for improvement in health and performance. It welcomes papers on developments in nutritional research tools and novel technologies.

    Read the blog 'Let thy food be thy medicine and thy medicine be thy food' to find out more about the aims and scope, and see what our editors have to say in the launch editorial.

     

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    International Journal of Retina and Vitreous is now accepting submissions

    This is the official publication of the Brazilian Retina and Vitreous Society. The journal focuses on the ophthalmic subspecialty of vitreoretinal disorders and aims to provide a stimulating forum for discussion of clinical, scientific, and socioeconomic issues of greatest concern to clinicians who care for patients with retinal diseases.

    Led by the editors, Jay Duker, Director of the New England Eye Center, and Eduardo Rodrigues, professor at Federal University of São Paulo, it aims to be the leading international journal in the field of retina research. 

    Visit the journal website for more information.

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    Research Involvement and Engagement has now opened for submissions

    An innovative, health and social care journal that focuses on the patient.

    Led by two Editors-in-Chief: Sophie Staniszewska, PPI lead at RCN Research Institute, University of Warwick, UK, and Richard Stephens, a patient advocate in research, who has overcome a number of health challenges. This collaboration between a patient and an academic signals "our intention to work towards the co-production of knowledge that informs health care practice."

    The journal will have a novel structure, co-produced by all key stakeholders, including patients, academics, policy makers and service users. All articles within the journal will be reviewed by both academics and patients, with both reports carrying equal weight in the editorial decision.

    "We want to walk the walk as well as talk the talk, and we look forward to you joining us as fellow travellers on our journey, and as fellow contributors in this new journal.”

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    Climate Change Responses has now fully launched and has published its first articles

    An interdisciplinary journal dedicated to publishing exceptional research on ecological and evolutionary responses to climate change. The journal is especially interested in publishing ground-breaking work linking responses to environmental change across levels of biological organization, from individuals to ecosystems, and with an emphasis on species interactions.

    Read the interview with co-Editor-in-Chief, Frank Seebacher, to discover the aims and scope of Climate Change Responses and about Frank's own background as a research scientist. Find out more about the importance of studying the ecological impacts of climate change with co-Editor-in-Chief Eric Post interview with Biome

     

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