Detecting those at risk of Alzheimers

Specific questions in an informant-rated questionnaire designed to detect Alzheimers Disease are also able to discriminate between normal memory loss and amnesic mild cognitive impairment, allowing earlier identification of those at higher risk of developing Alzheimers Disease.

Treatment strategies for VTEC

In light of the verotoxigenic E. coli (VTEC) European epidemic in 2011, Goldwater and Bettelheim comment on the complex pathogenesis of these strains and recommend a multi-targeted approach to current and future treatment strategies.

Managing STEC outbreaks

Improvements in management strategies to control Shiga toxin-producing E. coli (STEC) outbreaks are discussed by Dirk Werber et al, who advocate early detection via careful surveillance and investigation of food source, as well as integration of molecular data.

Crocodilian genome sequencing

An Open Letter describing the project to sequence the genomes of the saltwater crocodile, the American alligator and the Indian gharial

Neuroprotective role for microglia

Ramified microglia, previously branded as 'resting', protect hippocampal neurons against excitotoxicity according to research published in Journal of Neuroinflammation. Mariko Howe and Ben Barres discuss how these findings add to a growing recognition of active roles for microglia in health and disease.