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76.

1513
Accesses

Research article   Open Access Highly Accessed

Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral blood

Boryana S Stamova, Michelle Apperson, Wynn L Walker, Yingfang Tian, Huichun Xu, Peter Adamczy, Xinhua Zhan, Da-Zhi Liu, Bradley P Ander, Isaac H Liao, Jeffrey P Gregg, Renee J Turner, Glen Jickling, Lisa Lit, Frank R Sharp BMC Medical Genomics 2009, 2:49 (5 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

77.

1497
Accesses

Technical advance   Open Access Highly Accessed

Genotyping panel for assessing response to cancer chemotherapy

Zunyan Dai, Audrey C Papp, Danxin Wang, Heather Hampel, Wolfgang Sadee BMC Medical Genomics 2008, 1:24 (11 June 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

78.

1495
Accesses

Research article   Open Access

Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

Luca A Lotta, Mark Wang, Jin Yu, Ida Martinelli, Fuli Yu, Serena M Passamonti, Dario Consonni, Emanuela Pappalardo, Marzia Menegatti, Steven E Scherer, Lora L Lewis, Humeira Akbar, Yuanqing Wu, Matthew N Bainbridge, Donna M Muzny, Pier M Mannucci, Richard A Gibbs, Flora Peyvandi BMC Medical Genomics 2012, 5:7 (21 February 2012)

Abstract | Full text | PDF | PubMed

79.

1477
Accesses

Research article   Open Access

Optimally splitting cases for training and testing high dimensional classifiers

Kevin K Dobbin, Richard M Simon BMC Medical Genomics 2011, 4:31 (8 April 2011)

Abstract | Full text | PDF | PubMed

80.

1464
Accesses

Research article   Open Access

Signaling pathway networks mined from human pituitary adenoma proteomics data

Xianquan Zhan, Dominic M Desiderio BMC Medical Genomics 2010, 3:13 (28 April 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

81.

1463
Accesses

Research article   Open Access Highly Accessed

Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes

Jac C Charlesworth, Joanne E Curran, Matthew P Johnson, Harald HH Göring, Thomas D Dyer, Vincent P Diego, Jack W Kent, Michael C Mahaney, Laura Almasy, Jean W MacCluer, Eric K Moses, John Blangero BMC Medical Genomics 2010, 3:29 (15 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Cigarette smoking influences the expression of large networks of genes within a range of functional categories including immune response, cell death, cancer, natural killer cell signaling and xenobiotic metabolism, offering insights into induced system-wide pathological processes.

82.

1443
Accesses

Research article   Open Access Highly Accessed

Whole genome identification of Mycobacterium tuberculosis vaccine candidates by comprehensive data mining and bioinformatic analyses

Anat Zvi, Naomi Ariel, John Fulkerson, Jerald C Sadoff, Avigdor Shafferman BMC Medical Genomics 2008, 1:18 (28 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

83.

1442
Accesses

Research article   Open Access

Direct integration of intensity-level data from Affymetrix and Illumina microarrays improves statistical power for robust reanalysis

Arran K Turnbull, Robert R Kitchen, Alexey A Larionov, Lorna Renshaw, J Dixon, Andrew H Sims BMC Medical Genomics 2012, 5:35 (21 August 2012)

Abstract | Full text | PDF | PubMed

84.

1435
Accesses

Research article   Open Access Highly Accessed

Analyzing the regulation of metabolic pathways in human breast cancer

Gunnar Schramm, Eva-Maria Surmann, Stefan Wiesberg, Marcus Oswald, Gerhard Reinelt, Roland Eils, Rainer König BMC Medical Genomics 2010, 3:39 (10 September 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

85.

1426
Accesses

Research article   Open Access Highly Accessed

MicroRNA-34a modulates genes involved in cellular motility and oxidative phosphorylation in neural precursors derived from human umbilical cord mesenchymal stem cells

Shing-Jyh Chang, Shun-Long Weng, Jui-Yu Hsieh, Tao-Yeuan Wang, Margaret Chang, Hsei-Wei Wang BMC Medical Genomics 2011, 4:65 (19 September 2011)

Abstract | Full text | PDF | PubMed

86.

1425
Accesses

Research article   Open Access Highly Accessed

Detailed transcriptome atlas of the pancreatic beta cell

Burak Kutlu, David Burdick, David Baxter, Joanne Rasschaert, Daisy Flamez, Decio L Eizirik, Nils Welsh, Nathan Goodman, Leroy Hood BMC Medical Genomics 2009, 2:3 (15 January 2009)

Abstract | Full text | PDF | PubMed

87.

1423
Accesses

Research article   Open Access

High-throughput detection of aberrant imprint methylation in the ovarian cancer by the bisulphite PCR-Luminex method

Hitoshi Hiura, Hiroaki Okae, Hisato Kobayash, Naoko Miyauchi, Fumi Sato, Akiko Sato, Fumihiko Suzuki, Satoru Nagase, Junichi Sugawara, Kunihiko Nakai, Nobuo Yaegashi, Takahiro Arima BMC Medical Genomics 2012, 5:8 (26 March 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Aberrant patterns of methylation are found in samples from patients with ovarian cancer using the new bisulphate PCR-Luminex (BPL) method, highlighting H19 and PEG1 as potential biomarkers for the disease.

88.

1423
Accesses

Research article   Open Access

Microarray analysis of peripheral blood lymphocytes from ALS patients and the SAFE detection of the KEGG ALS pathway

Jean-Luc C Mougeot, Zhen Li, Andrea E Price, Fred A Wright, Benjamin R Brooks BMC Medical Genomics 2011, 4:74 (25 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

89.

1418
Accesses

Research article   Open Access

Histotype-specific copy-number alterations in ovarian cancer

Ruby YunJu Huang, Geng Bo Chen, Noriomi Matsumura, Hung-Cheng Lai, Seiichi Mori, Jingjing Li, Meng Kang Wong, Ikuo Konishi, Jean-Paul Thiery, Liang Goh BMC Medical Genomics 2012, 5:47 (18 October 2012)

Abstract | Full text | PDF | PubMed

90.

1416
Accesses

Research article   Open Access

Skeletal muscle alterations and exercise performance decrease in erythropoietin-deficient mice: a comparative study

Laurence Mille-Hamard, Veronique L Billat, Elodie Henry, Blandine Bonnamy, Florence Joly, Philippe Benech, Eric Barrey BMC Medical Genomics 2012, 5:29 (29 June 2012)

Abstract | Full text | PDF | PubMed

91.

1413
Accesses

Research article   Open Access Highly Accessed

The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice

Nicole JW de Wit, Hanneke Bosch-Vermeulen, Philip J de Groot, Guido JEJ Hooiveld, Mechteld Bromhaar, Jenny Jansen, Michael Müller, Roelof van der Meer BMC Medical Genomics 2008, 1:14 (6 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000

92.

1404
Accesses

Research article   Open Access Highly Accessed

Integrative analysis of next generation sequencing for small non-coding RNAs and transcriptional regulation in Myelodysplastic Syndromes

Dominik Beck, Steve Ayers, Jianguo Wen, Miriam B Brandl, Tuan D Pham, Paul Webb, Chung-Che Chang, Xiaobo Zhou BMC Medical Genomics 2011, 4:19 (23 February 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

93.

1399
Accesses

Research article   Open Access

Immune genes are associated with human glioblastoma pathology and patient survival

Elodie Vauléon, Avril Tony, Abderrahmane Hamlat, Amandine Etcheverry, Dan Chiforeanu, Philippe Menei, Jean Mosser, Véronique Quillien, Marc Aubry BMC Medical Genomics 2012, 5:41 (14 September 2012)

Abstract | Full text | PDF | PubMed

94.

1397
Accesses

Research article   Open Access

Mitochondrial proteomics of nasopharyngeal carcinoma metastasis

Jianping Liu, Xianquan Zhan, Maoyu Li, Guoqing Li, Pengfei Zhang, Zhefeng Xiao, Meiying Shao, Fang Peng, Rong Hu, Zhuchu Chen BMC Medical Genomics 2012, 5:62 (6 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

95.

1372
Accesses

Software   Open Access

CNVassoc: Association analysis of CNV data using R

Isaac Subirana, Ramon Diaz-Uriarte, Gavin Lucas, Juan R Gonzalez BMC Medical Genomics 2011, 4:47 (24 May 2011)

Abstract | Full text | PDF | PubMed

96.

1355
Accesses

Research article   Open Access Highly Accessed

Gene expression in the prefrontal cortex during adolescence: implications for the onset of schizophrenia

Laura W Harris, Helen E Lockstone, Phillipp Khaitovich, Cynthia Weickert, Maree J Webster, Sabine Bahn BMC Medical Genomics 2009, 2:28 (20 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

97.

1354
Accesses

Research article   Open Access

Pivotal role of the muscle-contraction pathway in cryptorchidism and evidence for genomic connections with cardiomyopathy pathways in RASopathies

Carlo V Cannistraci, Jernej Ogorevc, Minja Zorc, Timothy Ravasi, Peter Dovc, Tanja Kunej BMC Medical Genomics 2013, 6:5 (14 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

98.

1350
Accesses

Research article   Open Access

Gene expression in cardiac tissues from infants with idiopathic conotruncal defects

Douglas C Bittel, Merlin G Butler, Nataliya Kibiryeva, Jennifer A Marshall, Jie Chen, Gary K Lofland, James E O'Brien BMC Medical Genomics 2011, 4:1 (5 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

99.

1328
Accesses

Research article   Open Access

Evaluation of the bacterial diversity of Pressure ulcers using bTEFAP pyrosequencing

Drake M Smith, David E Snow, Eric Rees, Ann M Zischkau, J Delton Hanson, Randall D Wolcott, Yan Sun, Jennifer White, Shashi Kumar, Scot E Dowd BMC Medical Genomics 2010, 3:41 (21 September 2010)

Abstract | Full text | PDF | PubMed | F1000 Biology

100.

1327
Accesses

Research article   Open Access Highly Accessed

Identification of disease-causing genes using microarray data mining and Gene Ontology

Azadeh Mohammadi, Mohammad H Saraee, Mansoor Salehi BMC Medical Genomics 2011, 4:12 (26 January 2011)

Abstract | Full text | PDF | PubMed

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