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1.

12751
Accesses

Review   Open Access Highly Accessed

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

Douglas B Kell BMC Medical Genomics 2009, 2:2 (8 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Douglas Kell reviews the role of iron-catalysed free radicals in disease, which underpin the behavior of many physiological and pathological processes, and considers the need for better understanding using an integrative, systems-level approach.

2.

5276
Accesses

Research article   Open Access Highly Accessed

PAM50 Breast Cancer Subtyping by RT-qPCR and Concordance with Standard Clinical Molecular Markers

Roy RL Bastien, Álvaro Rodríguez-Lescure, Mark TW Ebbert, Aleix Prat, Blanca Munárriz, Leslie Rowe, Patricia Miller, Manuel Ruiz-Borrego, Daniel Anderson, Bradley Lyons, Isabel Álvarez, Tracy Dowell, David Wall, Miguel Seguí, Lee Barley, Kenneth M Boucher, Emilio Alba, Lisa Pappas, Carole A Davis, Ignacio Aranda, Christiane Fauron, Inge J Stijleman, José Palacios, Antonio Antón, Eva Carrasco, Rosalía Caballero, Matthew J Ellis, Torsten O Nielsen, Charles M Perou, Mark Astill, Philip S Bernard, Miguel Martín et al. BMC Medical Genomics 2012, 5:44 (4 October 2012)

Abstract | Full text | PDF | PubMed

3.

4812
Accesses

Research article   Open Access Highly Accessed

Global analysis of DNA methylation in early-stage liver fibrosis

Yoko Komatsu, Tsuyoshi Waku, Naoya Iwasaki, Wakana Ono, Chie Yamaguchi, Junn Yanagisawa BMC Medical Genomics 2012, 5:5 (27 January 2012)

Abstract | Full text | PDF | PubMed

4.

4676
Accesses

Technical advance   Open Access Highly Accessed

Noninvasive Fetal Trisomy (NIFTY) test: an advanced noninvasive prenatal diagnosis methodology for fetal autosomal and sex chromosomal aneuploidies

Fuman Jiang, Jinghui Ren, Fang Chen, Yuqiu Zhou, Jiansheng Xie, Shan Dan, Yue Su, Jianhong Xie, Baomin Yin, Wen Su, Huakun Zhang, Wei Wang, Xianghua Chai, Linhua Lin, Hui Guo, Qiyun Li, Peipei Li, Yuying Yuan, Xiaoyu Pan, Yihan Li, Lifu Liu, Huifei Chen, Zhaoling Xuan, Shengpei Chen, Chunlei Zhang, Hongyun Zhang, Zhongming Tian, Zhengyu Zhang, Hui Jiang, Lijian Zhao, Weimou Zheng, Songgang Li, Yingrui Li, Jun Wang, Jian Wang, Xiuqing Zhang et al. BMC Medical Genomics 2012, 5:57 (1 December 2012)

Abstract | Full text | PDF | PubMed

5.

4038
Accesses

Research article   Open Access Highly Accessed

Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

Martin Kerick, Melanie Isau, Bernd Timmermann, Holger Sültmann, Ralf Herwig, Sylvia Krobitsch, Georg Schaefer, Irmgard Verdorfer, Georg Bartsch, Helmut Klocker, Hans Lehrach, Michal R Schweiger BMC Medical Genomics 2011, 4:68 (29 September 2011)

Abstract | Full text | PDF | PubMed

6.

3644
Accesses

Research article   Open Access Highly Accessed

A systematic comparison and evaluation of high density exon arrays and RNA-seq technology used to unravel the peripheral blood transcriptome of sickle cell disease

Nalini Raghavachari, Jennifer Barb, Yanqin Yang, Poching Liu, Kimberly Woodhouse, Daniel Levy, Christopher J O‘Donnell, Peter J Munson, Gregory J Kato BMC Medical Genomics 2012, 5:28 (29 June 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology

7.

3553
Accesses

Research article   Open Access Highly Accessed

A target based approach identifies genomic predictors of breast cancer patient response to chemotherapy

Robin M Hallett, Gregory Pond, John A Hassell BMC Medical Genomics 2012, 5:16 (11 May 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Two new gene expression signatures can predict how breast cancer tumors will respond to two of the common kinds of chemotherapy, highlighting the potential of target-based gene expression indices to predict patient response to drug therapy.

8.

3437
Accesses

Research article   Open Access Highly Accessed

The effects of MicroRNA transfections on global patterns of gene expression in ovarian cancer cells are functionally coordinated

Shubin W Shahab, Lilya V Matyunina, Christopher G Hill, Lijuan Wang, Roman Mezencev, L Walker, John F McDonald BMC Medical Genomics 2012, 5:33 (1 August 2012)

Abstract | Full text | PDF | PubMed

9.

3399
Accesses

Research article   Open Access Highly Accessed

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors

Andrey Loboda, Michael Nebozhyn, Rich Klinghoffer, Jason Frazier, Michael Chastain, William Arthur, Brian Roberts, Theresa Zhang, Melissa Chenard, Brian Haines, Jannik Andersen, Kumiko Nagashima, Cloud Paweletz, Bethany Lynch, Igor Feldman, Hongyue Dai, Pearl Huang, James Watters BMC Medical Genomics 2010, 3:26 (30 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

3318
Accesses

Research article   Open Access Highly Accessed

DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?

Nahid Turan, Mohamed F Ghalwash, Sunita Katari, Christos Coutifaris, Zoran Obradovic, Carmen Sapienza BMC Medical Genomics 2012, 5:10 (12 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Profiling of inter-individual DNA methylation differences in neonates has identified 23 genes that account for 70-87% of variance in birth weight, whilst traditional gene expression profiling identified a far smaller proportion.

11.

3148
Accesses

Research article   Open Access Highly Accessed

Batch effect correction for genome-wide methylation data with Illumina Infinium platform

Zhifu Sun, High Chai, Yanhong Wu, Wendy M White, Krishna V Donkena, Christopher J Klein, Vesna D Garovic, Terry M Therneau, Jean-Pierre A Kocher BMC Medical Genomics 2011, 4:84 (16 December 2011)

Abstract | Full text | PDF | PubMed

12.

2988
Accesses

Research article   Open Access Highly Accessed

Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities

Reinhold J Medina, Christina L O'Neill, Mark Sweeney, Jasenka Guduric-Fuchs, Tom A Gardiner, David A Simpson, Alan W Stitt BMC Medical Genomics 2010, 3:18 (13 May 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000

13.

2945
Accesses

Research article   Open Access Highly Accessed

MicroRNA profiling of diverse endothelial cell types

Matthew N McCall, Oliver A Kent, Jianshi Yu, Karen Fox-Talbot, Ari L Zaiman, Marc K Halushka BMC Medical Genomics 2011, 4:78 (2 November 2011)

Abstract | Full text | PDF | PubMed

14.

2842
Accesses

Research article   Open Access Highly Accessed

An in silico analysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma

Zhaohui Luo, Liyang Zhang, Zheng Li, Xiayu Li, Gang Li, Haibo Yu, Chen Jiang, Yafei Dai, Xiaofang Guo, Juanjuan Xiang, Guiyuan Li BMC Medical Genomics 2012, 5:3 (19 January 2012)

Abstract | Full text | PDF | PubMed

15.

2675
Accesses

Correspondence   Open Access Highly Accessed

The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies

Catherine A McCarty, Rex L Chisholm, Christopher G Chute, Iftikhar J Kullo, Gail P Jarvik, Eric B Larson, Rongling Li, Daniel R Masys, Marylyn D Ritchie, Dan M Roden, Jeffery P Struewing, Wendy A Wolf, the eMERGE Team BMC Medical Genomics 2011, 4:13 (26 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

16.

2661
Accesses

Research article   Open Access Highly Accessed

Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

Christopher G Bell, Andrew E Teschendorff, Vardhman K Rakyan, Alexander P Maxwell, Stephan Beck, David A Savage BMC Medical Genomics 2010, 3:33 (5 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

17.

2657
Accesses

Research article   Open Access Highly Accessed

Impact of RNA degradation on gene expression profiling

Lennart Opitz, Gabriela Salinas-Riester, Marian Grade, Klaus Jung, Peter Jo, Georg Emons, B Michael Ghadimi, Tim Beißbarth, Jochen Gaedcke BMC Medical Genomics 2010, 3:36 (9 August 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

2622
Accesses

Research article   Open Access Highly Accessed

Saliva samples are a viable alternative to blood samples as a source of DNA for high throughput genotyping

Jean E Abraham, Mel J Maranian, Inmaculada Spiteri, Roslin Russell, Susan Ingle, Craig Luccarini, Helena M Earl, Paul PD Pharoah, Alison M Dunning, Carlos Caldas BMC Medical Genomics 2012, 5:19 (30 May 2012)

Abstract | Full text | PDF | PubMed

19.

2538
Accesses

Review   Open Access Highly Accessed

Completion of the swine genome will simplify the production of swine as a large animal biomedical model

Eric M Walters, Eckhard Wolf, Jeffery J Whyte, Jiude Mao, Simone Renner, Hiroshi Nagashima, Eiji Kobayashi, Jianguo Zhao, Kevin D Wells, John K Critser, Lela K Riley, Randall S Prather BMC Medical Genomics 2012, 5:55 (15 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Eric M Walters and colleagues review the pig as a large animal biomedical model and how the publication of the swine genome sequence will further advance its utility for understanding human disease, transgenesis and xenotransplantation.

20.

2361
Accesses

Research article   Open Access Highly Accessed

MicroRNA expression signature in human abdominal aortic aneurysms

Matthew C Pahl, Kimberly Derr, Gabor Gäbel, Irene Hinterseher, James R Elmore, Charles M Schworer, Thomas C Peeler, David P Franklin, John L Gray, David J Carey, Gerard Tromp, Helena Kuivaniemi BMC Medical Genomics 2012, 5:25 (15 June 2012)

Abstract | Full text | PDF | PubMed

21.

2351
Accesses

Research article   Open Access

Identification of genes with a correlation between copy number and expression in gastric cancer

Lei Cheng, Ping Wang, Sheng Yang, Yanqing Yang, Qing Zhang, Wen Zhang, Huasheng Xiao, Hengjun Gao, Qinghua Zhang BMC Medical Genomics 2012, 5:14 (4 May 2012)

Abstract | Full text | PDF | PubMed

22.

2305
Accesses

Research article   Open Access Highly Accessed

Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival

Nicola VL Serão, Kristin R Delfino, Bruce R Southey, Jonathan E Beever, Sandra L Rodriguez-Zas BMC Medical Genomics 2011, 4:49 (7 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

23.

2293
Accesses

Research article   Open Access Highly Accessed

Exploring the oral microbiota of children at various developmental stages of their dentition in the relation to their oral health

Wim Crielaard, Egija Zaura, Annemarie A Schuller, Susan M Huse, Roy C Montijn, Bart JF Keijser BMC Medical Genomics 2011, 4:22 (4 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

2288
Accesses

Research article   Open Access Highly Accessed

Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles

Julia Tchou, Andrew V Kossenkov, Lisa Chang, Celine Satija, Meenhard Herlyn, Louise C Showe, Ellen Puré BMC Medical Genomics 2012, 5:39 (6 September 2012)

Abstract | Full text | PDF | PubMed

25.

2281
Accesses

Research article   Open Access Highly Accessed

Modeling microRNA-mRNA Interactions Using PLS Regression in Human Colon Cancer

Xiaohong Li, Ryan Gill, Nigel GF Cooper, Jae Yoo, Susmita Datta BMC Medical Genomics 2011, 4:44 (19 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

26.

2277
Accesses

Database   Open Access

The Roche Cancer Genome Database 2.0

Jan Küntzer, Daniela Maisel, Hans-Peter Lenhof, Stefan Klostermann, Helmut Burtscher BMC Medical Genomics 2011, 4:43 (17 May 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The enlarged Roche Cancer Genome Database integrates information from a number of human mutation databases and mutation data curated from the literature, with an improved interface and search functionality over the earlier version.

27.

2217
Accesses

Research article   Open Access Highly Accessed

MicroRNA profiling of a CD133+ spheroid-forming subpopulation of the OVCAR3 human ovarian cancer cell line

Eun Nam, Maria Lee, Ga Yim, Jae Kim, Sunghoon Kim, Sang Kim, Young Kim BMC Medical Genomics 2012, 5:18 (29 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

28.

2195
Accesses

Research article   Open Access

Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform

Sarah De Keulenaer, Jan Hellemans, Steve Lefever, Jean-Pierre Renard, Joachim De Schrijver, Hendrik Van de Voorde, Mohammad Tabatabaiefar, Filip Van Nieuwerburgh, Daisy Flamez, Filip Pattyn, Bieke Scharlaken, Dieter Deforce, Sofie Bekaert, Wim Van Criekinge, Jo Vandesompele, Guy Van Camp, Paul Coucke BMC Medical Genomics 2012, 5:17 (18 May 2012)

Abstract | Full text | PDF | PubMed

29.

2124
Accesses

Research article   Open Access Highly Accessed

Interaction of a traditional Chinese Medicine (PHY906) and CPT-11 on the inflammatory process in the tumor microenvironment

Ena Wang, Scott Bussom, Jinguo Chen, Courtney Quinn, Davide Bedognetti, Wing Lam, Fulan Guan, Zaoli Jiang, Yichao Mark, Yingdong Zhao, David F Stroncek, Jeffrey White, Francesco M Marincola, Yung-Chi Cheng BMC Medical Genomics 2011, 4:38 (11 May 2011)

Abstract | Full text | PDF | PubMed

30.

2114
Accesses

Research article   Open Access Highly Accessed

Prediction of HIV-1 virus-host protein interactions using virus and host sequence motifs

Perry Evans, William Dampier, Lyle Ungar, Aydin Tozeren BMC Medical Genomics 2009, 2:27 (18 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

31.

2104
Accesses

Research article   Open Access

Discriminating lymphomas and reactive lymphadenopathy in lymph node biopsies by gene expression profiling

To Ha Loi, Anna Campain, Adam Bryant, Tim J Molloy, Mark Lutherborrow, Jennifer Turner, Yee Yang, David DF Ma BMC Medical Genomics 2011, 4:27 (31 March 2011)

Abstract | Full text | PDF | PubMed

32.

2092
Accesses

Research article   Open Access Highly Accessed

Defining the genomic signature of the parous breast

Suraj Peri, Ricardo de Cicco, Julia Santucci-Pereira, Michael Slifker, Eric A Ross, Irma H Russo, Patricia A Russo, Alan A Arslan, Ilana Belitskaya-Lévy, Anne Zeleniuch-Jacquotte, Pal Bordas, Per Lenner, Janet Åhman, Yelena Afanasyeva, Robert Johansson, Fathima Sheriff, Göran Hallmans, Paolo Toniolo, Jose Russo BMC Medical Genomics 2012, 5:46 (11 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Post-menopausal women who have previously given birth show differential gene expression in breast tissue compared to those who have not, with the affected pathways in RNA splicing and processing potentially contributing to their lowered breast cancer risk

33.

2079
Accesses

Research article   Open Access Highly Accessed

Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets

Bertalan Mesko, Szilard Poliska1, Andrea Szegedi, Zoltan Szekanecz, Karoly Palatka, Maria Papp, Laszlo Nagy BMC Medical Genomics 2010, 3:15 (5 May 2010)

Abstract | Full text | PDF | PubMed

34.

2071
Accesses

Research article   Open Access Highly Accessed

A genome-wide DNA methylation study in colorectal carcinoma

Muhammad G Kibriya, Maruf Raza, Farzana Jasmine, Shantanu Roy, Rachelle Paul-Brutus, Ronald Rahaman, Charlotte Dodsworth, Muhammad Rakibuz-Zaman, Mohammed Kamal, Habibul Ahsan BMC Medical Genomics 2011, 4:50 (23 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

35.

2070
Accesses

Research article   Open Access Highly Accessed

Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice

Wilma T Steegenga, Nicole JW de Wit, Mark V Boekschoten, Noortje IJssennagger, Carolien Lute, Shohreh Keshtkar, Mechteld M Bromhaar, Ellen Kampman, Lisette C de Groot, Michael Muller BMC Medical Genomics 2012, 5:38 (28 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The small intestine and colons of aging mice do not show marked changes in expression of genes involved in metabolic processes, however immune response and inflammation gene expression increases and aging-induced global hypomethylation is also present.

36.

2020
Accesses

Research article   Open Access Highly Accessed

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

Adam I Riker, Steven A Enkemann, Oystein Fodstad, Suhu Liu, Suping Ren, Christopher Morris, Yaguang Xi, Paul Howell, Brandon Metge, Rajeev S Samant, Lalita A Shevde, Wenbin Li, Steven Eschrich, Adil Daud, Jingfang Ju, Jaime Matta BMC Medical Genomics 2008, 1:13 (28 April 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

37.

2015
Accesses

Research article   Open Access Highly Accessed

Deep RNA sequencing analysis of readthrough gene fusions in human prostate adenocarcinoma and reference samples

Serban Nacu, Wenlin Yuan, Zhengyan Kan, Deepali Bhatt, Celina Rivers, Jeremy Stinson, Brock A Peters, Zora Modrusan, Kenneth Jung, Somasekar Seshagiri, Thomas D Wu BMC Medical Genomics 2011, 4:11 (24 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

38.

1996
Accesses

Debate   Open Access Highly Accessed

"Who owns your poop?": insights regarding the intersection of human microbiome research and the ELSI aspects of biobanking and related studies

Alice K Hawkins, Kieran C O'Doherty BMC Medical Genomics 2011, 4:72 (7 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

39.

1993
Accesses

Research article   Open Access Highly Accessed

2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting

Freek G Bouwman, Baukje de Roos, Isabel Rubio-Aliaga, L Katie Crosley, Susan J Duthie, Claus Mayer, Graham Horgan, Abigael C Polley, Carolin Heim, Susan LM Coort, Chris T Evelo, Francis Mulholland, Ian T Johnson, Ruan M Elliott, Hannelore Daniel, Edwin CM Mariman BMC Medical Genomics 2011, 4:24 (25 March 2011)

Abstract | Full text | PDF | PubMed

40.

1978
Accesses

Research article   Open Access Highly Accessed

EMT is the dominant program in human colon cancer

Andre Loboda, Michael V Nebozhyn, James W Watters, Carolyne A Buser, Peter Shaw, Pearl S Huang, Laura Van't Veer, Rob AEM Tollenaar, David B Jackson, Deepak Agrawal, Hongyue Dai, Timothy J Yeatman BMC Medical Genomics 2011, 4:9 (20 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The intrinsic first principal component (PC1) signature, tightly correlated with epithelial-mesenchymal transition (EMT), is highly prognostic for colon cancer recurrence and may also aid in sub classifying multiple types of cancer and their novel therapeutics.

41.

1970
Accesses

Software   Open Access Highly Accessed

Genotator: A disease-agnostic tool for genetic annotation of disease

Dennis P Wall, Rimma Pivovarov, Mark Tong, Jae-Yoon Jung, Vincent A Fusaro, Todd F DeLuca, Peter J Tonellato BMC Medical Genomics 2010, 3:50 (29 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

42.

1940
Accesses

Research article   Open Access

Development of a blood-based gene expression algorithm for assessment of obstructive coronary artery disease in non-diabetic patients

Michael R Elashoff, James A Wingrove, Philip Beineke, Susan E Daniels, Whittemore G Tingley, Steven Rosenberg, Szilard Voros, William E Kraus, Geoffrey S Ginsburg, Robert S Schwartz, Stephen G Ellis, Naheem Tahirkheli, Ron Waksman, John McPherson, Alexandra J Lansky, Eric J Topol BMC Medical Genomics 2011, 4:26 (28 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A validated biomarker signature of coronary artery disease (CAD) based on a non-invasive blood test of classifier genes and demographic factors may accurately asses the likelihood of obstructive CAD in non-diabetic patients.

43.

1926
Accesses

Research article   Open Access Highly Accessed

Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines

Kevin CH Ha, Emilie Lalonde, Lili Li, Luca Cavallone, Rachael Natrajan, Maryou B Lambros, Costas Mitsopoulos, Jarle Hakas, Iwanka Kozarewa, Kerry Fenwick, Chris J Lord, Alan Ashworth, Anne Vincent-Salomon, Mark Basik, Jorge S Reis-Filho, Jacek Majewski, William D Foulkes BMC Medical Genomics 2011, 4:75 (27 October 2011)

Abstract | Full text | PDF | PubMed

44.

1906
Accesses

Research article   Open Access Highly Accessed

Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer

Meng Li, Curt Balch, John S Montgomery, Mikyoung Jeong, Jae Chung, Pearlly Yan, Tim HM Huang, Sun Kim, Kenneth P Nephew BMC Medical Genomics 2009, 2:34 (8 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

45.

1888
Accesses

Research article   Open Access Highly Accessed

Meta-analysis of multiple microarray datasets reveals a common gene signature of metastasis in solid tumors

Marla H Daves, Susan G Hilsenbeck, Ching C Lau, Tsz-Kwong Man BMC Medical Genomics 2011, 4:56 (7 July 2011)

Abstract | Full text | PDF | PubMed

46.

1857
Accesses

Research article   Open Access

Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

Jarkko Soronen, Pirkka-Pekka Laurila, Jussi Naukkarinen, Ida Surakka, Samuli Ripatti, Matti Jauhiainen, Vesa M Olkkonen, Hannele Yki-Järvinen BMC Medical Genomics 2012, 5:9 (3 April 2012)

Abstract | Full text | PDF | PubMed

47.

1832
Accesses

Research article   Open Access Highly Accessed

Cancer patient perceptions on the ethical and legal issues related to biobanking

Zubin Master, Jaime O Claudio, Christen Rachul, Jean CY Wang, Mark D Minden, Timothy Caulfield BMC Medical Genomics 2013, 6:8 (8 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

In a survey of perceptions of leukemia patients towards biobanking research ethics, majorities favoured one-time consent and retaining the right to withdrawal, and almost all favoured being informed of incidental findings relevant to their health.

48.

1829
Accesses

Research article   Open Access Highly Accessed

Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics

Diego Diez, Susumu Goto, John V Fahy, David J Erle, Prescott G Woodruff, Åsa M Wheelock, Craig E Wheelock BMC Medical Genomics 2012, 5:27 (19 June 2012)

Abstract | Full text | PDF | PubMed

49.

1821
Accesses

Research article   Open Access Highly Accessed

An integrative approach to identifying cancer chemoresistance-associated pathways

Shih-Yi Chao, Jung-Hsien Chiang, A-Mei Huang, Woan-Shan Chang BMC Medical Genomics 2011, 4:23 (24 March 2011)

Abstract | Full text | PDF | PubMed

50.

1806
Accesses

Research article   Open Access Highly Accessed

Identification of DNA methylation changes associated with human gastric cancer

Jung-Hoon Park, Jinah Park, Jung Kyoon Choi, Jaemyun Lyu, Min-Gyun Bae, Young-Gun Lee, Jae-Bum Bae, Dong Yoon Park, Han-Kwang Yang, Tae-You Kim, Young-Joon Kim BMC Medical Genomics 2011, 4:82 (2 December 2011)

Abstract | Full text | PDF | PubMed

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