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1.
8970 Accesses
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Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
Douglas B Kell BMC Medical Genomics 2009, 2:2 (8 January 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Douglas Kell reviews the role of iron-catalysed free radicals in disease, which underpin the behavior of many physiological and pathological processes, and considers the need for better understanding using an integrative, systems-level approach.
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2.
3968 Accesses
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A genome-wide DNA methylation study in colorectal carcinoma
Muhammad G Kibriya, Maruf Raza, Farzana Jasmine, Shantanu Roy, Rachelle Paul-Brutus, Ronald Rahaman, Charlotte Dodsworth, Muhammad Rakibuz-Zaman, Mohammed Kamal, Habibul Ahsan BMC Medical Genomics 2011, 4:50 (23 June 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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3.
3099 Accesses
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Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus
Christopher G Bell, Andrew E Teschendorff, Vardhman K Rakyan, Alexander P Maxwell, Stephan Beck, David A Savage BMC Medical Genomics 2010, 3:33 (5 August 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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4.
2622 Accesses
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Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity
Martin Kerick, Melanie Isau, Bernd Timmermann, Holger Sültmann, Ralf Herwig, Sylvia Krobitsch, Georg Schaefer, Irmgard Verdorfer, Georg Bartsch, Helmut Klocker, Hans Lehrach, Michal R Schweiger BMC Medical Genomics 2011, 4:68 (29 September 2011)
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5.
2597 Accesses
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Molecular prediction for atherogenic risks across different cell types of leukocytes
Feng Cheng, Ellen C Keeley, Jae K Lee BMC Medical Genomics 2012, 5:2 (13 January 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
An new set of 56 gene expression biomarkers could be used to predict early atherosclerosis from leukocytes before the symptoms of heart disease have developed, and this test can be further refined to identify very high risk patients.
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6.
2583 Accesses
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"Who owns your poop?": insights regarding the intersection of human microbiome research and the ELSI aspects of biobanking and related studies
Alice K Hawkins, Kieran C O'Doherty BMC Medical Genomics 2011, 4:72 (7 October 2011)
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7.
2578 Accesses
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Deep RNA sequencing analysis of readthrough gene fusions in human prostate adenocarcinoma and reference samples
Serban Nacu, Wenlin Yuan, Zhengyan Kan, Deepali Bhatt, Celina Rivers, Jeremy Stinson, Brock A Peters, Zora Modrusan, Kenneth Jung, Somasekar Seshagiri, Thomas D Wu BMC Medical Genomics 2011, 4:11 (24 January 2011)
Abstract | Full text | PDF | PubMed
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8.
2523 Accesses
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The eMERGE Network: A consortium of biorepositories linked to electronic medical records data for conducting genomic studies
Catherine A McCarty, Rex L Chisholm, Christopher G Chute, Iftikhar J Kullo, Gail P Jarvik, Eric B Larson, Rongling Li, Daniel R Masys, Marylyn D Ritchie, Dan M Roden, Jeffery P Struewing, Wendy A Wolf, the eMERGE Team BMC Medical Genomics 2011, 4:13 (26 January 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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9.
2513 Accesses
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Meta-analysis of multiple microarray datasets reveals a common gene signature of metastasis in solid tumors
Marla H Daves, Susan G Hilsenbeck, Ching C Lau, Tsz-Kwong Man BMC Medical Genomics 2011, 4:56 (7 July 2011)
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10.
2488 Accesses
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Modeling microRNA-mRNA Interactions Using PLS Regression in Human Colon Cancer
Xiaohong Li, Ryan Gill, Nigel GF Cooper, Jae Yoo, Susmita Datta BMC Medical Genomics 2011, 4:44 (19 May 2011)
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11.
2420 Accesses
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A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors
Andrey Loboda, Michael Nebozhyn, Rich Klinghoffer, Jason Frazier, Michael Chastain, William Arthur, Brian Roberts, Theresa Zhang, Melissa Chenard, Brian Haines, Jannik Andersen, Kumiko Nagashima, Cloud Paweletz, Bethany Lynch, Igor Feldman, Hongyue Dai, Pearl Huang, James Watters BMC Medical Genomics 2010, 3:26 (30 June 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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12.
2354 Accesses
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Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities
Reinhold J Medina, Christina L O'Neill, Mark Sweeney, Jasenka Guduric-Fuchs, Tom A Gardiner, David A Simpson, Alan W Stitt BMC Medical Genomics 2010, 3:18 (13 May 2010)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Medicine | F1000 Biology
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13.
2324 Accesses
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2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting
Freek G Bouwman, Baukje de Roos, Isabel Rubio-Aliaga, L Katie Crosley, Susan J Duthie, Claus Mayer, Graham Horgan, Abigael C Polley, Carolin Heim, Susan LM Coort, Chris T Evelo, Francis Mulholland, Ian T Johnson, Ruan M Elliott, Hannelore Daniel, Edwin CM Mariman BMC Medical Genomics 2011, 4:24 (25 March 2011)
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14.
2322 Accesses
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Discovering functional modules by identifying recurrent and mutually exclusive mutational patterns in tumors
Christopher A Miller, Stephen H Settle, Erik P Sulman, Kenneth D Aldape, Aleksandar Milosavljevic BMC Medical Genomics 2011, 4:34 (14 April 2011)
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15.
2301 Accesses
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Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival
Nicola VL Serão, Kristin R Delfino, Bruce R Southey, Jonathan E Beever, Sandra L Rodriguez-Zas BMC Medical Genomics 2011, 4:49 (7 June 2011)
Abstract | Full text | PDF | PubMed |
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16.
2171 Accesses
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Interaction of a traditional Chinese Medicine (PHY906) and CPT-11 on the inflammatory process in the tumor microenvironment
Ena Wang, Scott Bussom, Jinguo Chen, Courtney Quinn, Davide Bedognetti, Wing Lam, Fulan Guan, Zaoli Jiang, Yichao Mark, Yingdong Zhao, David F Stroncek, Jeffrey White, Francesco M Marincola, Yung-Chi Cheng BMC Medical Genomics 2011, 4:38 (11 May 2011)
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17.
2106 Accesses
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Identification of DNA methylation changes associated with human gastric cancer
Jung-Hoon Park, Jinah Park, Jung Kyoon Choi, Jaemyun Lyu, Min-Gyun Bae, Young-Gun Lee, Jae-Bum Bae, Dong Yoon Park, Han-Kwang Yang, Tae-You Kim, Young-Joon Kim BMC Medical Genomics 2011, 4:82 (2 December 2011)
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18.
2039 Accesses
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miRNA signature associated with outcome of gastric cancer patients following chemotherapy
Chang Kim, Hark K Kim, R Luke Rettig, Joseph Kim, Eunbyul T Lee, Olga Aprelikova, Il J Choi, David J Munroe, Jeffrey E Green BMC Medical Genomics 2011, 4:79 (23 November 2011)
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19.
2032 Accesses
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MicroRNA profiling of diverse endothelial cell types
Matthew N McCall, Oliver A Kent, Jianshi Yu, Karen Fox-Talbot, Ari L Zaiman, Marc K Halushka BMC Medical Genomics 2011, 4:78 (2 November 2011)
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20.
2028 Accesses
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Integrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma
Siyuan Zheng, William P Tansey, Scott W Hiebert, Zhongming Zhao BMC Medical Genomics 2011, 4:62 (8 August 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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21.
2016 Accesses
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The functional cancer map: A systems-level synopsis of genetic deregulation in cancer
Markus Krupp, Thorsten Maass, Jens U Marquardt, Frank Staib, Tobias Bauer, Rainer König, Stefan Biesterfeld, Peter R Galle, Achim Tresch, Andreas Teufel BMC Medical Genomics 2011, 4:53 (30 June 2011)
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22.
2002 Accesses
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Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines
Kevin CH Ha, Emilie Lalonde, Lili Li, Luca Cavallone, Rachael Natrajan, Maryou B Lambros, Costas Mitsopoulos, Jarle Hakas, Iwanka Kozarewa, Kerry Fenwick, Chris J Lord, Alan Ashworth, Anne Vincent-Salomon, Mark Basik, Jorge S Reis-Filho, Jacek Majewski, William D Foulkes BMC Medical Genomics 2011, 4:75 (27 October 2011)
Abstract | Full text | PDF | PubMed
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23.
1914 Accesses
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EMT is the dominant program in human colon cancer
Andre Loboda, Michael V Nebozhyn, James W Watters, Carolyne A Buser, Peter Shaw, Pearl S Huang, Laura Van't Veer, Rob AEM Tollenaar, David B Jackson, Deepak Agrawal, Hongyue Dai, Timothy J Yeatman BMC Medical Genomics 2011, 4:9 (20 January 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
The intrinsic first principal component (PC1) signature, tightly correlated with epithelial-mesenchymal transition (EMT), is highly prognostic for colon cancer recurrence and may also aid in sub classifying multiple types of cancer and their novel therapeutics.
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24.
1883 Accesses
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Integrative analysis of next generation sequencing for small non-coding RNAs and transcriptional regulation in Myelodysplastic Syndromes
Dominik Beck, Steve Ayers, Jianguo Wen, Miriam B Brandl, Tuan D Pham, Paul Webb, Chung-Che Chang, Xiaobo Zhou BMC Medical Genomics 2011, 4:19 (23 February 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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25.
1878 Accesses
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Identification of candidate genes linking systemic inflammation to atherosclerosis; results of a human in vivo LPS infusion study
Suthesh Sivapalaratnam, Rosienne Farrugia, Max Nieuwdorp, Cordelia F Langford, Rachel T van Beem, Stephanie Maiwald, Jaap Zwaginga, Arief Gusnanto, Nicholas A Watkins, Mieke D Trip, Willem H Ouwehand BMC Medical Genomics 2011, 4:64 (10 August 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Changes in gene expression of circulating monocytes among healthy volunteers, following stimulation of an inflammatory response by infusion of lipopolysaccharide, is able to identify candidate genes linking systemic inflammation and atherosclerosis.
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