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Volume 5 (2012) - April 2012

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Research article   Open Access

Interaction among apoptosis-associated sequence variants and joint effects on aggressive prostate cancer

Nicole A Lavender, Erica N Rogers, Susan Yeyeodu, James Rudd, Ting Hu, Jie Zhang, Guy N Brock, Kevin S Kimbro, Jason H Moore, David W Hein, La Creis R Kidd BMC Medical Genomics 2012, 5:11 (30 April 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?

Nahid Turan, Mohamed F Ghalwash, Sunita Katari, Christos Coutifaris, Zoran Obradovic, Carmen Sapienza BMC Medical Genomics 2012, 5:10 (12 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Profiling of inter-individual DNA methylation differences in neonates has identified 23 genes that account for 70-87% of variance in birth weight, whilst traditional gene expression profiling identified a far smaller proportion.

Research article   Open Access

Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

Jarkko Soronen, Pirkka-Pekka Laurila, Jussi Naukkarinen, Ida Surakka, Samuli Ripatti, Matti Jauhiainen, Vesa M Olkkonen, Hannele Yki-Järvinen BMC Medical Genomics 2012, 5:9 (3 April 2012)

Abstract | Full text | PDF | PubMed