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Volume 2 (2009) - May 2009

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Research article   Open Access

Identification of gene co-regulatory modules and associated cis-elements involved in degenerative heart disease

Charles G Danko, Arkady M Pertsov BMC Medical Genomics 2009, 2:31 (28 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Hypermethylation of genomic 3.3-kb repeats is frequent event in HPV-positive cervical cancer

Alexey N Katargin, Larissa S Pavlova, Fjodor L Kisseljov, Natalia P Kisseljova BMC Medical Genomics 2009, 2:30 (27 May 2009)

Abstract | Full text | PDF | PubMed

Commentary   Open Access

The A's, G's, C's, and T's of health disparities

Edward Ramos, Charles Rotimi BMC Medical Genomics 2009, 2:29 (22 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Lessons from the genetics of prostate cancer and heart failure treatment response highlight that correct usage of genomic information that avoids racial or social generalizations has the potential to lessen health disparities in the population.

Research article   Open Access Highly Accessed

Gene expression in the prefrontal cortex during adolescence: implications for the onset of schizophrenia

Laura W Harris, Helen E Lockstone, Phillipp Khaitovich, Cynthia Weickert, Maree J Webster, Sabine Bahn BMC Medical Genomics 2009, 2:28 (20 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

Research article   Open Access Highly Accessed

Prediction of HIV-1 virus-host protein interactions using virus and host sequence motifs

Perry Evans, William Dampier, Lyle Ungar, Aydin Tozeren BMC Medical Genomics 2009, 2:27 (18 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Data integration from two microarray platforms identifies bi-allelic genetic inactivation of RIC8A in a breast cancer cell line

Aslaug Muggerud, Henrik Edgren, Maija Wolf, Kristine Kleivi, Emelyne Dejeux, Jörg Tost, Therese Sørlie, Olli Kallioniemi BMC Medical Genomics 2009, 2:26 (11 May 2009)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

The RIC8A gene is identified as a putative breast cancer tumor-suppressor by a novel combination of array-CGH with non-sense mediated mRNA decay and gene expression data, and shows association with aggressive TP53 mutant tumors in vitro.

Research article   Open Access

Similar gene expression profiles of sporadic, PGL2-, and SDHD-linked paragangliomas suggest a common pathway to tumorigenesis

Erik F Hensen, Jelle J Goeman, Jan Oosting, Andel GL Van der Mey, Pancras CW Hogendoorn, Cor WRJ Cremers, Peter Devilee, Cees J Cornelisse BMC Medical Genomics 2009, 2:25 (11 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Network analysis of human glaucomatous optic nerve head astrocytes

Tatiana Nikolskaya, Yuri Nikolsky, Tatiana Serebryiskaya, Svetlana Zvereva, Eugene Sviridov, Zoltan Dezso, Eugene Rahkmatulin, Richard J Brennan, Nick Yankovsky, Sanjoy K Bhattacharya, Olga Agapova, M Rosario Hernandez, Valery I Shestopalov BMC Medical Genomics 2009, 2:24 (9 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Microarray analysis of RNA extracted from formalin-fixed, paraffin-embedded and matched fresh-frozen ovarian adenocarcinomas

Grazyna Fedorowicz, Steve Guerrero, Thomas D Wu, Zora Modrusan BMC Medical Genomics 2009, 2:23 (8 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Technical advance   Open Access

Identification of microbial DNA in human cancer

Christopher G Duncan, Rebecca J Leary, Jimmy Lin, Jordan Cummins, Chunhui Di, Carl F Schaefer, Tian-Li Wang, Gregory J Riggins, Jennifer Edwards, Darell Bigner, Levy Kopelovich, Bert Vogelstein, Kenneth W Kinzler, Victor E Velculescu, Hai Yan BMC Medical Genomics 2009, 2:22 (8 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Novel pathogens associated with human cancer can now be pin-pointed using a digital karyotyping approach that screens a library of sample sequence tags from the diseased tissue against a database of microbial genomes.

Research article   Open Access

High-resolution analysis of copy number alterations and associated expression changes in ovarian tumors

Peter M Haverty, Lawrence S Hon, Joshua S Kaminker, John Chant, Zemin Zhang BMC Medical Genomics 2009, 2:21 (6 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment


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