Ancestral exposure to stress epigenetically programs preterm birth risk and adverse maternal and newborn outcomes
BMC Medicine 2014, 12:121 (7 August 2014)
Prenatal stress across generations in rats leads to reduced gestational length, poor pregnancy outcomes and epigenetic changes in somatic cells, suggesting a family history of stress could be linked to preterm birth and pregnancy outcomes in humans.
Video Q & A: The impact of stress. An interview with George Chrousos
BMC Medicine 2014, 12:102 (20 June 2014)
In this video Q&A, we interview George Chrousos on the impact of stress on chronic non-communicable disorders, and discuss the physiological and economic factors that affect stress, as well as how it can be prevented.
Interaction between stress and the BDNF Val66Met polymorphism in depression: a systematic review and meta-analysis
BMC Medicine 2014, 12:7 (16 January 2014)
Evidence from a meta-analysis suggests the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism interacts more strongly with life stress than childhood adversity in depression, although better methods are needed to measure life stress.
Cardiac-specific catalase overexpression rescues anthrax lethal toxin-induced cardiac contractile dysfunction: role of oxidative stress and autophagy
BMC Medicine 2012, 10:134 (7 November 2012)
Catalase protects against effects of anthrax infection in mice by rescuing toxin-induced cardiac contractile dysfunction and intracellular calcium anomalies, via regulation of mitochondrial function and autophagy, providing therapeutic promise in the management of toxin induced cardiovascular complications.