Better prioritization to increase research value and decrease waste
BMC Medicine 2015, 13:244 (29 September 2015)
A recent study demonstrates gaps between research needs and ongoing research in endocrinology; Agnes Dechartres and Philippe Ravaud discuss how this contributes to research waste, highlighting that systemic registration of gaps may aide better prioritization.
Is the endocrine research pipeline broken? A systematic evaluation of the Endocrine Society clinical practice guidelines and trial registration
BMC Medicine 2015, 13:187 (12 August 2015)
In a systematic assessment of the endocrine research pipeline, current clinical trials are only addressing 20% of the known knowledge gaps, suggesting high inefficiency and highlighting the need to link the research agenda to evidence gaps.
Shifting from glucose diagnosis to the new HbA1c diagnosis reduces the capability of the Finnish Diabetes Risk Score (FINDRISC) to screen for glucose abnormalities within a real-life primary healthcare preventive strategy
BMC Medicine 2013, 11:45 (21 February 2013)
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Metabolism, diet and...
The predictive ability of a screening tool for diabetes is reduced when the proposed new hemoglobin-based criteria are used for diagnosis instead of glucose, suggesting that glucose should be measured to assess diabetes risk using this score.