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		Research article The VHL-dependent regulation of microRNAs in renal cancer Calida S Neal, Michael Z Michael, Lesley H Rawlings, Mark B Van der Hoek, Jonathan M Gleadle BMC Medicine 2010, 8:64 (21 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In renal cancer pathogenesis, microRNA regulation by the von-Hippel-Lindeau (VHL) tumour suppressor is controlled via both hypoxia induced factor-dependent and independent mechanisms, further clarifying the mechanisms behind anaerobic respiration in tumours.
		Debate Normalisation process theory: a framework for developing, evaluating and implementing complex interventions Elizabeth Murray, Shaun Treweek, Catherine Pope, Anne MacFarlane, Luciana Ballini, Christopher Dowrick, Tracy Finch, Anne Kennedy, Frances Mair, Catherine O'Donnell, Bie Ong, Tim Rapley, Anne Rogers, Carl May BMC Medicine 2010, 8:63 (20 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Despite an increase in both research and development of complex health interventions, implementation into routine practice has often proved difficult, showing a need for a consistent framework to aid this transition between phases.
		Research article Surveys of current status in biomedical science grant review: funding organisations' and grant reviewers' perspectives Sara Schroter, Trish Groves, Liselotte Højgaard BMC Medicine 2010, 8:62 (20 October 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A new survey shows biomedical research grants are becoming increasingly more difficult to peer-review - many of these problems could be addressed by developing uniform requirements for a more consistent, transparent, and user friendly system.
		Commentary Internet addiction: a 21^stcentury epidemic? Dimitri A Christakis BMC Medicine 2010, 8:61 (18 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Unfettered access to the internet, combined with an ever-increasing online ‘community’, has led to the rise of a new epidemic in the form of Internet addiction and those with underlying psychological conditions potentially at greatest risk.
		Research article The effects of increased dose of exercise-based therapies to enhance motor recovery after stroke: a systematic review and meta-analysis Emma V Cooke, Kathryn Mares, Allan Clark, Raymond C Tallis, Valerie M Pomeroy BMC Medicine 2010, 8:60 (13 October 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Increasing the dose of exercise-based therapies appears to be beneficial to motor recovery after stroke, including improvement in arm and walking motor skills.
		Research article Assessment of the quality and variability of health information on chronic pain websites using the DISCERN instrument Jatin Kaicker, Victoria Debono, Wilfred Dang, Norman Buckley, Lehana Thabane BMC Medicine 2010, 8:59 (12 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The internet is a crucial resource for pain-related health information but a cautious approach is advisable - an analysis of the quality and variability of information available online sheds light on how to discriminate between sources.
		Research article Predictors of pain intensity and persistence in a prospective Italian cohort of patients with herpes zoster: relevance of smoking, trauma and antiviral therapy Giustino Parruti, Monica Tontodonati, Cristina Rebuzzi, Ennio Polilli, Federica Sozio, Augusta Consorte, Adriana Agostinone, Francesco Di Masi, Gabriele Congedo, Domenico D'Antonio, Carla Granchelli, Claudio D'Amario, Carlo Carunchio, Lucio Pippa, Lamberto Manzoli, Antonio Volpi, the VZV Pain Study Group BMC Medicine 2010, 8:58 (11 October 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Post-herpetic neuralgia, a nervous pain commonly associated with the prevalent varicella zoster virus, may be exacerbated by a number of novel risk factors including age, trauma or surgery at the affected site and potentially most interestingly – smoking
		Commentary Decisions at the end of life: have we come of age? Linda Emanuel, Karen Scandrett BMC Medicine 2010, 8:57 (8 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Emanuel and Scandrett discuss recent progress in achieving appropriate and dignified advance planning for end of life decision-making, and outline future areas of investigation and improvement to continue this process
		Commentary An introduction to standardized clinical nomenclature for dysmorphic features: the Elements of Morphology project Leslie G Biesecker BMC Medicine 2010, 8:56 (4 October 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Leslie Biesecker discusses the Elements of Morphology project, the aim of which is to encourage the standardization of terminology used to describe human structural malformations, including outlining practical implementation to ensure better reporting in the literature.
		Commentary The case for home monitoring in hypertension Paul L Padfield BMC Medicine 2010, 8:55 (27 September 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Paul Padfield discusses why patient self-monitoring of blood pressure is important in managing hypertension, including the ways in which it can lead to better calculation of risk, cost-effective diagnosis and improved blood pressure control
		Research article Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers Siv K Bøhn, Mari C Myhrstad, Magne Thoresen, Marit Holden, Anette Karlsen, Siv Tunheim, Iris Erlund, Mette Svendsen, Ingebjørg Seljeflot, Jan Ø Moskaug, Asim K Duttaroy, Petter Laake, Harald Arnesen, Serena Tonstad, Andrew Collins, Christan A Drevon, Rune Blomhoff BMC Medicine 2010, 8:54 (16 September 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The health benefits of a plant-based diet for smokers may be mediated through the up-regulation of cellular stress defence genes, including those associated with apoptosis and DNA repair
		Research article Routine resite of peripheral intravenous devices every 3 days did not reduce complications compared with clinically indicated resite: a randomised controlled trial Claire M Rickard, Damhnat McCann, Jane Munnings, Matthew R McGrail BMC Medicine 2010, 8:53 (10 September 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Routine removal and relocation of peripheral intravenous (IV) devices is no more effective in the prevention of complications than a single cannula per course of treatment, indicating only clinically-indicated relocation should be used.
		Research article Chest compressions before defibrillation for out-of-hospital cardiac arrest: A meta-analysis of randomized controlled clinical trials Pascal Meier, Paul Baker, Daniel Jost, Ian Jacobs, Bettina Henzi, Guido Knapp, Comilla Sasson BMC Medicine 2010, 8:52 (9 September 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Pre-treatment with chest compression-only cardiopulmonary resuscitation (CPR) prior to defibrillation is no better than applying immediate defibrillation in out-of-hospital cardiac arrests, in contrast to previous studies suggesting a potential benefit of CPR first.
		Research article Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety Alan G Wade, Ian Ford, Gordon Crawford, Alex McConnachie, Tali Nir, Moshe Laudon, Nava Zisapel BMC Medicine 2010, 8:51 (16 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Prolonged-release melatonin, a widely available drug chiefly used in the treatment of primary insomnia, works independently of endogenous melatonin levels with significant positive effects and excellent tolerance in the elderly population.
		Commentary Enhancement drugs: are there limits to what we should enhance and why? Morten Hesse BMC Medicine 2010, 8:50 (3 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Morten Hesse contends that drugs often used for social or performance enhancement should be subject to public health interventions not specifically centred on preventing their use, but rather on prevention of harm.
		Correction Development of lower limb range of motion from early childhood to adolescence in cerebral palsy: a population-based study Eva Nordmark, Gunnar Hägglund, Henrik Lauge-Pedersen, Philippe Wagner, Lena Westbom BMC Medicine 2010, 8:49 (28 July 2010) Abstract \| Full text \| PDF \| PubMed
		Research article Relationship between knee and ankle degeneration in a population of organ donors Carol Muehleman, Arkady Margulis, Won C Bae, Koichi Masuda BMC Medicine 2010, 8:48 (28 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary In osteoarthritis, gender and body type have a greater effect on knee joint integrity than ankle and degeneration is not balanced between joints, suggesting that increasing differences in condition result in mismatched limb kinetics and disease progression.
		Research article Targeted exercise against osteoporosis: A systematic review and meta-analysis for optimising bone strength throughout life Riku Nikander, Harri Sievänen, Ari Heinonen, Robin M Daly, Kirsti Uusi-Rasi, Pekka Kannus BMC Medicine 2010, 8:47 (21 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Long-term supervised exercise appears to substantially increase lower extremity bone strength in children, an augmentation not observed in adults, increasing the need for improved studies to more closely examine this phenomenon.
		Review Managing hyperemesis gravidarum: a multimodal challenge JK Jueckstock, R Kaestner, I Mylonas BMC Medicine 2010, 8:46 (15 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Better understanding by medical personnel of the etiology and diagnosis of hyperemesis gravidarum, a severe or prolonged form of the nausea and vomiting experienced by pregnant women, would help management and treatment of this condition.
		Commentary Hypoxia-specific targets in cancer therapy: role of splice variants Dirk Vordermark BMC Medicine 2010, 8:45 (12 July 2010) Abstract \| Full text \| PDF \| PubMed
		Research article Hypoxia inducible factor 1α gene (HIF-1α) splice variants: potential prognostic biomarkers in breast cancer Jean-Philippe Dales, Nathalie Beaufils, Monique Silvy, Christophe Picard, Vanessa Pauly, Vincent Pradel, Christine Formisano-Tréziny, Pascal Bonnier, Sophie Giusiano, Colette Charpin, Jean Gabert BMC Medicine 2010, 8:44 (12 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A splice variant of Hypoxia Inducible Factor-1 alpha (HIF-1a) is associated with an increased risk of metastasis in breast cancer and a worse prognosis, thus making it a potential prognostic biomarker
		Research article Neonatal hypothermia and associated risk factors among newborns of southern Nepal Luke C Mullany, Joanne Katz, Subarna K Khatry, Steven C LeClerq, Gary L Darmstadt, James M Tielsch BMC Medicine 2010, 8:43 (8 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary Season as well as weight are risk factors for neonatal hypothermia in newborns in southern Nepal, highlighting the need for an emphasis on year-round thermal care, early breastfeeding and maternal thermal care to compensate.
		Review Zinc Finger Nucleases as tools to understand and treat human diseases David Davis, David Stokoe BMC Medicine 2010, 8:42 (1 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary David Davis and David Stokoe discuss the development and use of designer zinc finger proteins as sequence specific tools in genomic manipulation, and their role as investigative and therapeutic instruments.
		Review Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan H Teede, A Deeks, L Moran BMC Medicine 2010, 8:41 (30 June 2010) Abstract \| Full text \| PDF \| PubMed \| 2 comments \| Editor’s summary Polycystic ovary syndrome, a clinically diverse condition affecting up to 1 in 5 women of reproductive age, manifests with an array of complications which are reviewed together with their detrimental influence on quality of life.
		Research article Reduced acquisition and reactivation of human papillomavirus infections among older women treated with cryotherapy: results from a randomized trial in South Africa Sylvia Taylor, Chunhui Wang, Thomas C Wright, Lynette Denny, Wei-Yann Tsai, Louise Kuhn BMC Medicine 2010, 8:40 (29 June 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Cervical cryotherapy significantly reduces the rate of newly-detected high-risk human papillomavirus in HIV-negative women when used as a treatment for high-grade cervical cancer precursors.

	All
		Research article The VHL-dependent regulation of microRNAs in renal cancer Calida S Neal, Michael Z Michael, Lesley H Rawlings, Mark B Van der Hoek, Jonathan M Gleadle BMC Medicine 2010, 8:64 (21 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In renal cancer pathogenesis, microRNA regulation by the von-Hippel-Lindeau (VHL) tumour suppressor is controlled via both hypoxia induced factor-dependent and independent mechanisms, further clarifying the mechanisms behind anaerobic respiration in tumours.
		Debate Normalisation process theory: a framework for developing, evaluating and implementing complex interventions Elizabeth Murray, Shaun Treweek, Catherine Pope, Anne MacFarlane, Luciana Ballini, Christopher Dowrick, Tracy Finch, Anne Kennedy, Frances Mair, Catherine O'Donnell, Bie Ong, Tim Rapley, Anne Rogers, Carl May BMC Medicine 2010, 8:63 (20 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Despite an increase in both research and development of complex health interventions, implementation into routine practice has often proved difficult, showing a need for a consistent framework to aid this transition between phases.
		Research article Surveys of current status in biomedical science grant review: funding organisations' and grant reviewers' perspectives Sara Schroter, Trish Groves, Liselotte Højgaard BMC Medicine 2010, 8:62 (20 October 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A new survey shows biomedical research grants are becoming increasingly more difficult to peer-review - many of these problems could be addressed by developing uniform requirements for a more consistent, transparent, and user friendly system.
		Commentary Internet addiction: a 21^stcentury epidemic? Dimitri A Christakis BMC Medicine 2010, 8:61 (18 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Unfettered access to the internet, combined with an ever-increasing online ‘community’, has led to the rise of a new epidemic in the form of Internet addiction and those with underlying psychological conditions potentially at greatest risk.
		Research article The effects of increased dose of exercise-based therapies to enhance motor recovery after stroke: a systematic review and meta-analysis Emma V Cooke, Kathryn Mares, Allan Clark, Raymond C Tallis, Valerie M Pomeroy BMC Medicine 2010, 8:60 (13 October 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Increasing the dose of exercise-based therapies appears to be beneficial to motor recovery after stroke, including improvement in arm and walking motor skills.
		Research article Assessment of the quality and variability of health information on chronic pain websites using the DISCERN instrument Jatin Kaicker, Victoria Debono, Wilfred Dang, Norman Buckley, Lehana Thabane BMC Medicine 2010, 8:59 (12 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The internet is a crucial resource for pain-related health information but a cautious approach is advisable - an analysis of the quality and variability of information available online sheds light on how to discriminate between sources.
		Research article Predictors of pain intensity and persistence in a prospective Italian cohort of patients with herpes zoster: relevance of smoking, trauma and antiviral therapy Giustino Parruti, Monica Tontodonati, Cristina Rebuzzi, Ennio Polilli, Federica Sozio, Augusta Consorte, Adriana Agostinone, Francesco Di Masi, Gabriele Congedo, Domenico D'Antonio, Carla Granchelli, Claudio D'Amario, Carlo Carunchio, Lucio Pippa, Lamberto Manzoli, Antonio Volpi, the VZV Pain Study Group BMC Medicine 2010, 8:58 (11 October 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Post-herpetic neuralgia, a nervous pain commonly associated with the prevalent varicella zoster virus, may be exacerbated by a number of novel risk factors including age, trauma or surgery at the affected site and potentially most interestingly – smoking
		Commentary Decisions at the end of life: have we come of age? Linda Emanuel, Karen Scandrett BMC Medicine 2010, 8:57 (8 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment \| Editor’s summary Emanuel and Scandrett discuss recent progress in achieving appropriate and dignified advance planning for end of life decision-making, and outline future areas of investigation and improvement to continue this process
		Commentary An introduction to standardized clinical nomenclature for dysmorphic features: the Elements of Morphology project Leslie G Biesecker BMC Medicine 2010, 8:56 (4 October 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Leslie Biesecker discusses the Elements of Morphology project, the aim of which is to encourage the standardization of terminology used to describe human structural malformations, including outlining practical implementation to ensure better reporting in the literature.
		Commentary The case for home monitoring in hypertension Paul L Padfield BMC Medicine 2010, 8:55 (27 September 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Paul Padfield discusses why patient self-monitoring of blood pressure is important in managing hypertension, including the ways in which it can lead to better calculation of risk, cost-effective diagnosis and improved blood pressure control
		Research article Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers Siv K Bøhn, Mari C Myhrstad, Magne Thoresen, Marit Holden, Anette Karlsen, Siv Tunheim, Iris Erlund, Mette Svendsen, Ingebjørg Seljeflot, Jan Ø Moskaug, Asim K Duttaroy, Petter Laake, Harald Arnesen, Serena Tonstad, Andrew Collins, Christan A Drevon, Rune Blomhoff BMC Medicine 2010, 8:54 (16 September 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The health benefits of a plant-based diet for smokers may be mediated through the up-regulation of cellular stress defence genes, including those associated with apoptosis and DNA repair
		Research article Routine resite of peripheral intravenous devices every 3 days did not reduce complications compared with clinically indicated resite: a randomised controlled trial Claire M Rickard, Damhnat McCann, Jane Munnings, Matthew R McGrail BMC Medicine 2010, 8:53 (10 September 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Routine removal and relocation of peripheral intravenous (IV) devices is no more effective in the prevention of complications than a single cannula per course of treatment, indicating only clinically-indicated relocation should be used.
		Research article Chest compressions before defibrillation for out-of-hospital cardiac arrest: A meta-analysis of randomized controlled clinical trials Pascal Meier, Paul Baker, Daniel Jost, Ian Jacobs, Bettina Henzi, Guido Knapp, Comilla Sasson BMC Medicine 2010, 8:52 (9 September 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Pre-treatment with chest compression-only cardiopulmonary resuscitation (CPR) prior to defibrillation is no better than applying immediate defibrillation in out-of-hospital cardiac arrests, in contrast to previous studies suggesting a potential benefit of CPR first.
		Research article Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety Alan G Wade, Ian Ford, Gordon Crawford, Alex McConnachie, Tali Nir, Moshe Laudon, Nava Zisapel BMC Medicine 2010, 8:51 (16 August 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Prolonged-release melatonin, a widely available drug chiefly used in the treatment of primary insomnia, works independently of endogenous melatonin levels with significant positive effects and excellent tolerance in the elderly population.
		Commentary Enhancement drugs: are there limits to what we should enhance and why? Morten Hesse BMC Medicine 2010, 8:50 (3 August 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Morten Hesse contends that drugs often used for social or performance enhancement should be subject to public health interventions not specifically centred on preventing their use, but rather on prevention of harm.
		Correction Development of lower limb range of motion from early childhood to adolescence in cerebral palsy: a population-based study Eva Nordmark, Gunnar Hägglund, Henrik Lauge-Pedersen, Philippe Wagner, Lena Westbom BMC Medicine 2010, 8:49 (28 July 2010) Abstract \| Full text \| PDF \| PubMed
		Research article Relationship between knee and ankle degeneration in a population of organ donors Carol Muehleman, Arkady Margulis, Won C Bae, Koichi Masuda BMC Medicine 2010, 8:48 (28 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary In osteoarthritis, gender and body type have a greater effect on knee joint integrity than ankle and degeneration is not balanced between joints, suggesting that increasing differences in condition result in mismatched limb kinetics and disease progression.
		Research article Targeted exercise against osteoporosis: A systematic review and meta-analysis for optimising bone strength throughout life Riku Nikander, Harri Sievänen, Ari Heinonen, Robin M Daly, Kirsti Uusi-Rasi, Pekka Kannus BMC Medicine 2010, 8:47 (21 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Long-term supervised exercise appears to substantially increase lower extremity bone strength in children, an augmentation not observed in adults, increasing the need for improved studies to more closely examine this phenomenon.
		Review Managing hyperemesis gravidarum: a multimodal challenge JK Jueckstock, R Kaestner, I Mylonas BMC Medicine 2010, 8:46 (15 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Better understanding by medical personnel of the etiology and diagnosis of hyperemesis gravidarum, a severe or prolonged form of the nausea and vomiting experienced by pregnant women, would help management and treatment of this condition.
		Commentary Hypoxia-specific targets in cancer therapy: role of splice variants Dirk Vordermark BMC Medicine 2010, 8:45 (12 July 2010) Abstract \| Full text \| PDF \| PubMed
		Research article Hypoxia inducible factor 1α gene (HIF-1α) splice variants: potential prognostic biomarkers in breast cancer Jean-Philippe Dales, Nathalie Beaufils, Monique Silvy, Christophe Picard, Vanessa Pauly, Vincent Pradel, Christine Formisano-Tréziny, Pascal Bonnier, Sophie Giusiano, Colette Charpin, Jean Gabert BMC Medicine 2010, 8:44 (12 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A splice variant of Hypoxia Inducible Factor-1 alpha (HIF-1a) is associated with an increased risk of metastasis in breast cancer and a worse prognosis, thus making it a potential prognostic biomarker
		Research article Neonatal hypothermia and associated risk factors among newborns of southern Nepal Luke C Mullany, Joanne Katz, Subarna K Khatry, Steven C LeClerq, Gary L Darmstadt, James M Tielsch BMC Medicine 2010, 8:43 (8 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary Season as well as weight are risk factors for neonatal hypothermia in newborns in southern Nepal, highlighting the need for an emphasis on year-round thermal care, early breastfeeding and maternal thermal care to compensate.
		Review Zinc Finger Nucleases as tools to understand and treat human diseases David Davis, David Stokoe BMC Medicine 2010, 8:42 (1 July 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary David Davis and David Stokoe discuss the development and use of designer zinc finger proteins as sequence specific tools in genomic manipulation, and their role as investigative and therapeutic instruments.
		Review Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan H Teede, A Deeks, L Moran BMC Medicine 2010, 8:41 (30 June 2010) Abstract \| Full text \| PDF \| PubMed \| 2 comments \| Editor’s summary Polycystic ovary syndrome, a clinically diverse condition affecting up to 1 in 5 women of reproductive age, manifests with an array of complications which are reviewed together with their detrimental influence on quality of life.
		Research article Reduced acquisition and reactivation of human papillomavirus infections among older women treated with cryotherapy: results from a randomized trial in South Africa Sylvia Taylor, Chunhui Wang, Thomas C Wright, Lynette Denny, Wei-Yann Tsai, Louise Kuhn BMC Medicine 2010, 8:40 (29 June 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Cervical cryotherapy significantly reduces the rate of newly-detected high-risk human papillomavirus in HIV-negative women when used as a treatment for high-grade cervical cancer precursors.