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Volume 2 (2004) - September 2004

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Research article   Open Access Highly Accessed

Exposure to malaria affects the regression of hepatosplenomegaly after treatment for Schistosoma mansoni infection in Kenyan children

Mark Booth, Birgitte J Vennervald, Anthony E Butterworth, Henry C Kariuki, Clifford Amaganga, Gachuhi Kimani, Joseph K Mwatha, Amos Otedo, John H Ouma, David W Dunne BMC Medicine 2004, 2:36 (27 September 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The outcome of the treatment with praziquantel of the hepatosplenomegaly associated with schistosomaisis is adversely affected by the level of malaria exposure, highlighting the need to reassess the estimates and control of Schistosoma mansoni related morbidity.

Research article   Open Access Highly Accessed

Neoadjuvant or adjuvant therapy for resectable esophageal cancer: a systematic review and meta-analysis

Richard A Malthaner, Rebecca KS Wong, R Bryan Rumble, Lisa Zuraw, Members of the Gastrointestinal Cancer Disease Site Group of Cancer Care Ontario's Program in Evidence-based Care. BMC Medicine 2004, 2:35 (24 September 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A systematic review on the use of adjuvant and neoadjuvant therapy on esophageal cancer shows that surgery alone is the optimal treatment for those patients for whom a complete resection is possible.

Research article   Open Access Highly Accessed

Delta-9 tetrahydrocannabinol (THC) inhibits lytic replication of gamma oncogenic herpesviruses in vitro

Maria M Medveczky, Tracy A Sherwood, Thomas W Klein, Herman Friedman, Peter G Medveczky BMC Medicine 2004, 2:34 (15 September 2004)

Abstract | Full text | PDF | PubMed |  Editor’s summary

In cell cultures, the active ingredient of cannabis, delta-9-tetrahydrocannibol (THC), can inhibit the replication and activation of several gamma herpesviruses, including two that are associated with human tumors.

Research article   Open Access Highly Accessed

What do evidence-based secondary journals tell us about the publication of clinically important articles in primary healthcare journals?

Kathleen McKibbon, Nancy L Wilczynski, Robert Haynes BMC Medicine 2004, 2:33 (6 September 2004)

Abstract | Full text | PDF | PubMed | 1 comment |  Editor’s summary

An assessment of 60,000 articles from 170 healthcare journals finds that the majority of clinically useful articles in each discipline are published in a small subset of journals.

Research article   Open Access

Emergence of new Salmonella Enteritidis phage types in Europe? Surveillance of infections in returning travellers

Karin Nygård, Birgitta de Jong, Philippe J Guerin, Yvonne Andersson, Agneta Olsson, Johan Giesecke BMC Medicine 2004, 2:32 (2 September 2004)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A comprehensive database containing details of infections caught abroad by travellers could be used to highlight emerging infections worldwide and inform countries that have limited surveillance systems about possible disease outbreaks.