BMC Medicine is the flagship medical journal of the BMC series, publishing original research, commentaries and reviews that are either of significant interest to all areas of medicine and clinical practice, or provide key translational or clinical advances in a specific field.
- Sabina Alam PhD, BioMed Central
Review & comment
Analyzing genetic polymorphisms is important for the development of new cancer biomarkers; Wei Xu and colleagues review special considerations that must be taken into account when studying tumor genetics, and highlight the potential problems.
Jens Lundgren and colleagues argue for a more cautious approach to starting antiretroviral therapy, highlighting that there is no evidence from randomized trials to suggest the benefits of starting therapy early outweigh the potential harms.
Ricardo Franco and Michael Saag discuss the benefits of starting HIV therapy early, arguing that treatment should be given as soon as possible to reduce viral replication, prevent transmission and avoid the problems associated with inflammation.
Christopher Brightling and colleagues discuss the contribution of different cell types to airway smooth muscle hyperplasia, and describe how a greater understanding of these mechanisms will guide the development of new therapies for asthma.
Pascal Meier and colleagues discuss the relevance of collateral arteries in the heart, and describe recent evidence indicating these arteries have a protective role in preserving myocardial function in patients with coronary heart disease.
Neurological disorders, such as multiple sclerosis (MS) and leukoaraiosis have been associated with venous abnormalities that contribute to the pathophysiology; Clive Beggs reviews the evidence for this, concluding that the role of cerebral flow in MS remains unclear.
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Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition
Sabine Rohrmann, Kim Overvad, H B Bueno-de-Mesquita, Marianne U Jakobsen, Rikke Egeberg, Anne Tjønneland, Laura Nailler, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Vittorio Krogh, Domenico Palli, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Manuela M Bergmann, Heiner Boeing, Kuanrong Li, Rudolf Kaaks, Kay-Tee Khaw, Nicholas J Wareham, Francesca L Crowe, Timothy J Key, Androniki Naska, Antonia Trichopoulou, Dimitirios Trichopoulos, Max Leenders, Petra HM Peeters, Dagrun Engeset, Christine L Parr, Guri Skeie, Paula Jakszyn, María-José Sánchez, José M Huerta, M L Redondo, Aurelio Barricarte, Pilar Amiano, Isabel Drake, Emily Sonestedt, Göran Hallmans, Ingegerd Johansson, Veronika Fedirko, Isabelle Romieux, Pietro Ferrari, Teresa Norat, Anne C Vergnaud, Elio Riboli and J Linseisen
BMC Medicine 2013, 11:63
HIV thirty years on
Published: 21 May 2013
Last updated: 14 June 2013
Current Controversies in Psychiatry
Published: 14 May 2013
Last updated: 17 May 2013
World Asthma Day 2013: it's time to control asthma
Published: 3 May 2013