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BMC Medicine

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Editor-in-Chief
Melissa Norton, MD

Medical Editor
Jigisha Patel, MRCP PhD

In-house Editor
Robin Cassady-Cain PhD


Welcome to BMC Medicine published by BioMed Central
BMC Medicine - the flagship medical journal of the BMC series - publishes original research articles, commentaries and reviews in all areas of medical science and clinical practice. To be appropriate for BMC Medicine, articles need to be of outstanding quality, broad interest and special importance. BMC Medicine (ISSN 1741-7015) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Current Contents, Thomson Reuters (ISI) and Google Scholar.


BMC  Featured articles   

DNA Flickr photosdnaday and Gastric Adenocarcinoma Wikipedia
BMC Medicine 2010, 8:12
The -448A>G polymorphism in the DNA-methyltransferase-3A promoter region results in a two-fold increase in promoter activity and is associated with increased risk of gastric cancer, particularly among those under 60 years old.
Mammogram - Wikipedia
BMC Medicine 2010, 8:11
Italian programs for early rescreen following a negative mammogram detect women most likely to screen positive for breast cancer at the next scan, if kept within recommended levels, such programs can result in clinical benefits.
Womans back - Sharealike
BMC Medicine 2010, 8:10
The addition of the McKenzie exercise program to recommended primary care treatment for low back pain contributes a negligible improvement in short-term pain relief but results in reduced healthcare utilization.
heart monitoring electrodes on chest from flickr credit tomsaint
BMC Medicine 2010, 8:9
A novel score based on clinical findings may aid physicians in ruling out coronary heart disease in patients presenting with chest pain in the primary care setting.
wikimedia cc eleassar
BMC Medicine 2010, 8:8
A debate on current practice suggests inadequate health policies and poor training of health personnel leads to insufficient pain relief access in many countries, and may amount to a violation of human health care rights.


BMC  Latest articles published in BMC Medicine        [more info]


Research article
A functional polymorphism in the DNA methyltransferase 3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma
Hong Fan, Dongsheng Liu, Xuemei Qiu, Fengchang Qiao, Xianwei Su, Qingxiang Wu, Feng Zhang, Yunwei Song, Zhujiang Zhao, Wei Xie
BMC Medicine 2010, 8:12 (3February2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Incidence, detection, and tumour stage of breast cancer in a cohort of Italian women with negative screening mammography report recommending early (short-interval) rescreen
Alessandra Ravaioli, Flavia Foca, Americo Colamartini, Fabio Falcini, Carlo Naldoni, Alba C Finarelli, Priscilla Sassoli de Bianchi, Lauro Bucchi
BMC Medicine 2010, 8:11 (1February2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
The effectiveness of the McKenzie method in addition to first-line care for acute low back pain: a randomized controlled trial
Luciana AC Machado, Chris G Maher, Rob D Herbert, Helen Clare, James H McAuley
BMC Medicine 2010, 8:10 (26January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Ruling out coronary heart disease in primary care patients with chest pain: a clinical prediction score
Baris Gencer, Paul Vaucher, Lilli Herzig, Francois Verdon, Christiane Ruffieux, Stefan Boesner, Bernard Burnand, Thomas Bischoff, Norbert Donner-Banzhoff, Bernard Favrat
BMC Medicine 2010, 8:9 (21January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Debate
Access to pain treatment as a human right
Diederik Lohman, Rebecca Schleifer, Joseph J Amon
BMC Medicine 2010, 8:8 (20January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
An in-depth assessment of a diagnosis-based risk adjustment model based on national health insurance claims: the application of the Johns Hopkins Adjusted Clinical Group case-mix system in Taiwan
Hsien-Yen Chang, Jonathan P Weiner
BMC Medicine 2010, 8:7 (18January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Commentary
The interleukin-1 cluster, dyslipidaemia and risk of myocardial infarction
Bernard Keavney
BMC Medicine 2010, 8:6 (13January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
An evaluation of inflammatory gene polymorphisms in sibships discordant for premature coronary artery disease: the GRACE-IMMUNE study
Benjamin D Brown, Jeremie Nsengimana, Jennifer H Barrett, Richard A Lawrence, Lori Steiner, Suzanne Cheng, D Timothy Bishop, Nilesh J Samani, Stephen G Ball, Anthony J Balmforth, Alistair S Hall
BMC Medicine 2010, 8:5 (13January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles] [Cited on BioMed Central]

Research article
Suicide-related behaviors in older patients with new anti-epileptic drug use: data from the VA hospital system
Anne C Van Cott, Joyce A Cramer, Laurel A Copeland, John E Zeber, Michael A Steinman, Jeffrey J Dersh, Mark E Glickman, Eric M Mortensen, Megan E Amuan, Mary Jo Pugh
BMC Medicine 2010, 8:4 (11January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
A randomized phase II study of carboplatin plus pegylated liposomal doxorubicin versus carboplatin plus paclitaxel in platinum sensitive ovarian cancer patients: a Hellenic Cooperative Oncology Group study
Dimitrios Bafaloukos, Helena Linardou, Gerasimos Aravantinos, Christos Papadimitriou, Aristotelis Bamias, George Fountzilas, Haralambos P. Kalofonos, Paris Kosmidis, Eleni Timotheadou, Thomas Makatsoris, Epaminondas Samantas, Evangelos Briasoulis, Christos Christodoulou, Pavlos Papakostas, Dimitrios Pectasides, Athanasios M. Dimopoulos
BMC Medicine 2010, 8:3 (7January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]


BMC  Latest selected articles from BMC Biology


This list contains articles from BMC Biology that may be of interest to readers of BMC Medicine

Research article
Mild folate deficiency induces genetic and epigenetic instability and phenotype changes in prostate cancer cells
Gaia Bistulfi, Erika VanDette, Sei-Ichi Matsui, Dominic J Smiraglia
BMC Biology 2010, 8:6 (21January2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo
Annalisa Mancini, Susanne C Niemann-Seyde, Rdiger Pankow, Omar El Bounkari, Sabine Klebba-Frber, Alexandra Koch, Ewa Jaworska, Elaine Spooncer, Achim D Gruber, Anthony D Whetton, Teruko Tamura
BMC Biology 2010, 8:1 (5January2010)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]

Research article
Phylogeographic reconstruction of a bacterial species with high levels of lateral gene transfer
Talima Pearson, Philip Giffard, Stephen Beckstrom-Sternberg, Raymond Auerbach, Heidie Hornstra, Apichai Tuanyok, Erin P Price, Mindy B Glass, Benjamin Leadem, James S Beckstrom-Sternberg, Gerard J Allan, Jeffrey T Foster, David M Wagner, Richard T Okinaka, Siew Hoon Sim, Ofori Pearson, Zaining Wu, Jean Chang, Rajinder Kaul, Alex R Hoffmaster, Thomas S Brettin, Richard A Robison, Mark Mayo, Jay E Gee, Patrick Tan, Bart J Currie, Paul Keim
BMC Biology 2009, 7:78 (18November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Methodology article
Factors necessary to produce basoapical polarity in human glandular epithelium formed in conventional and high-throughput three-dimensional culture: example of the breast epithelium
Cedric Plachot, Lesley S Chaboub, Hibret A Adissu, Lei Wang, Albert Urazaev, Jennifer Sturgis, Elikplimi K Asem, Sophie A Lelivre
BMC Biology 2009, 7:77 (16November2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles] [Cited on BioMed Central]

Research article
Genetical genomic determinants of alcohol consumption in rats and humans
Boris Tabakoff, Laura Saba, Morton Printz, Pam Flodman, Colin Hodgkinson, David Goldman, George Koob, Heather N Richardson, Katerina Kechris, Richard L Bell, Norbert Hbner, Matthias Heinig, Michal Pravenec, Jonathan Mangion, Lucie Legault, Maurice Dongier, Katherine M Conigrave, John B Whitfield, John Saunders, Bridget Grant, Paula L Hoffman, WHO/ISBRA Study on State and Trait Markers of Alcoholism
BMC Biology 2009, 7:70 (27October2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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