BMC Medicine is the flagship medical journal of the BMC series, publishing original research, commentaries and reviews that are either of significant interest to all areas of medicine and clinical practice, or provide key translational or clinical advances in a specific field.

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  • Sabina Alam PhD, BioMed Central

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Selected articles

Review & comment

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    Considerations in cancer genetics

    Sevtap Savas, Geoffrey Liu, Wei Xu

    Analyzing genetic polymorphisms is important for the development of new cancer biomarkers; Wei Xu and colleagues review special considerations that must be taken into account when studying tumor genetics, and highlight the potential problems.

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    HIV therapy: start later

    Jens Lundgren, Abdel Babiker, Fred Gordin, Álvaro Borges, James Neaton

    Jens Lundgren and colleagues argue for a more cautious approach to starting antiretroviral therapy, highlighting that there is no evidence from randomized trials to suggest the benefits of starting therapy early outweigh the potential harms.

  • Wikipedia (Gary van der Merwe)

    HIV therapy: start early

    Ricardo Franco, Michael Saag

    Ricardo Franco and Michael Saag discuss the benefits of starting HIV therapy early, arguing that treatment should be given as soon as possible to reduce viral replication, prevent transmission and avoid the problems associated with inflammation.

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    Asthmatic airway remodeling

    Rachid Berair, Ruth Saunders, Christopher Brightling

    Christopher Brightling and colleagues discuss the contribution of different cell types to airway smooth muscle hyperplasia, and describe how a greater understanding of these mechanisms will guide the development of new therapies for asthma.

  • Meier et al (2013) BMC Medicine

    Collateral arteries of the heart

    Pascal Meier, Stephan Schirmer, Alexandra Lansky, Adam Timmis, Bertram Pitt, Christian Seiler

    Pascal Meier and colleagues discuss the relevance of collateral arteries in the heart, and describe recent evidence indicating these arteries have a protective role in preserving myocardial function in patients with coronary heart disease.

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    Venous defects in neurological disorders

    Clive Beggs

    Neurological disorders, such as multiple sclerosis (MS) and leukoaraiosis have been associated with venous abnormalities that contribute to the pathophysiology; Clive Beggs reviews the evidence for this, concluding that the role of cerebral flow in MS remains unclear.

Research

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BMC Medicine in the news

Meat consumption and mortality - results from the European Prospective Investigation into Cancer and Nutrition
Sabine Rohrmann, Kim Overvad, H B Bueno-de-Mesquita, Marianne U Jakobsen, Rikke Egeberg, Anne Tjønneland, Laura Nailler, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Vittorio Krogh, Domenico Palli, Salvatore Panico, Rosario Tumino, Fulvio Ricceri, Manuela M Bergmann, Heiner Boeing, Kuanrong Li, Rudolf Kaaks, Kay-Tee Khaw, Nicholas J Wareham, Francesca L Crowe, Timothy J Key, Androniki Naska, Antonia Trichopoulou, Dimitirios Trichopoulos, Max Leenders, Petra HM Peeters, Dagrun Engeset, Christine L Parr, Guri Skeie, Paula Jakszyn, María-José Sánchez, José M Huerta, M L Redondo, Aurelio Barricarte, Pilar Amiano, Isabel Drake, Emily Sonestedt, Göran Hallmans, Ingegerd Johansson, Veronika Fedirko, Isabelle Romieux, Pietro Ferrari, Teresa Norat, Anne C Vergnaud, Elio Riboli and J Linseisen
BMC Medicine 2013, 11:63

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