- Jean-Claude Desenclos, Institut de Veille Sanitaire
- Susanna Esposito, University of Milan
- Jorge Garbino, University Hospitals Geneva
- Pak Leung Ho, University of Hong Kong
- Sanjeev Krishna, St. George's, University of London
- Stephen Lawn, London School of Hygiene & Tropical Medicine
- Sepehr Tabrizi, The Royal Women's Hospital
- Carlo Torti, University 'Magna Graecia'
- Philippa Harris, BioMed Central
Following initiation of highly active anti-retroviral therapy there is a significant association between low CCL3L1 gene copy number and improved immune reconstitution in patients, which is not seen prior to the start of drug treatment.
Despite an observation that Herpes simplex virus type 2 (HSV-2) activity is associated with increased HIV viral load, definitive evidence linking HSV-2 seropositivity to accelerated HIV disease progression is lacking, as shown in this systematic review.
Prognosis after diagnosis of non-AIDS defining cancers (NADC), an important cause of morbidity and mortality in HIV-positive individuals, is poor but has improved slightly in recent years with modifiable risk factors, such as smoking, associated with poor outcomes.
High-sensitive c-reactive protein (hsCRP) independently predicts cardiovascular disease (CVD) risk in people with HIV receiving antiretroviral therapy, implicating hsCRP as a potential biomarker for CVD risk in this clinical sample.
Steve Lawn and colleagues discuss best practice in the design, conduct and interpretation of studies into Determine TB-LAM, a commercially available, lateral-flow urine ‘strip test’ assay, for tuberculosis diagnosis.
BMC Infectious Diseases 2013, 13:455
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