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Research article   Open Access

In-vitro inhibition of IFNγ+ iTreg mediated by monoclonal antibodies against cell surface determinants essential for iTreg function

Volker Daniel, Mahmoud Sadeghi, Haihao Wang, Gerhard Opelz BMC Immunology 2012, 13:47 (21 August 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Regulation of in vitro human T cell development through interleukin-7 deprivation and anti-CD3 stimulation

Ekta S Patel, Starlyn Okada, Kevin Hachey, Li-jun Yang, Scott K Durum, Jan S Moreb, Lung-Ji Chang BMC Immunology 2012, 13:46 (16 August 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Immune responses in the lungs of patients with tuberculous pleural effusion without pulmonary tuberculosis

Diana Qama, Won-Il Choi, Kun Kwon BMC Immunology 2012, 13:45 (13 August 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Fermented fish oil suppresses T helper 1/2 cell response in a mouse model of atopic dermatitis via generation of CD4+CD25+Foxp3+ T cells

Sang-Chul Han, Gyeoung-Jin Kang, Yeong-Jong Ko, Hee-Kyoung Kang, Sang-Wook Moon, Yong-Seok Ann, Eun-Sook Yoo BMC Immunology 2012, 13:44 (9 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Fermented fish oil (FFO) treatment in a mouse model of atopic dermatitis (AD) is associated with enrichment of CD4, CD25 and Foxp3 positive regulatory T cells at sites of inflammation, suggesting FFO may be effective in treating AD allergic symptoms.

Research article   Open Access Highly Accessed

Association of HLA-DR1 with the allergic response to the major mugwort pollen allergen: molecular background

Bernhard Knapp, Gottfried Fischer, Dries Van Hemelen, Ingrid Fae, Bernard Maillere, Christof Ebner, Wolfgang Schreiner, Barbara Bohle, Beatrice Jahn-Schmid BMC Immunology 2012, 13:43 (8 August 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

The peritoneal macrophage inflammatory profile in cirrhosis depends on the alcoholic or hepatitis C viral etiology and is related to ERK phosphorylation

Ana Tapia-Abellán, María Martínez-Esparza, Antonio J Ruiz-Alcaraz, Trinidad Hernández-Caselles, Cristina Martínez-Pascual, Manuel Miras-López, José Such, Rubén Francés, Pilar García-Peñarrubia BMC Immunology 2012, 13:42 (6 August 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Multifunctional role of dextran sulfate sodium for in vivo modeling of intestinal diseases

William A Rose, Kaori Sakamoto, Cynthia A Leifer BMC Immunology 2012, 13:41 (1 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A dextran sulfate sodium-induced experimental colitis model system in mice provides novel insights into the role of toll-like receptor 9 in intestinal repair and the etiology of intestinal bowel diseases.

Research article   Open Access Highly Accessed

Structural basis of LaDR5, a novel agonistic anti-death receptor 5 (DR5) monoclonal antibody, to inhibit DR5/TRAIL complex formation

Chunxia Qiao, Meiyun Hu, Leiming Guo, Ming Lv, Zhou Lin, Jing Geng, Xiaoling Lang, Xinying Li, Yan Li, Yuanfang Ma, Jiannan Feng, Beifen Shen BMC Immunology 2012, 13:40 (12 July 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Discordant antibody and cellular responses to Pneumocystis major surface glycoprotein variants in mice

Lisa R Bishop, Daniel Helman, Joseph A Kovacs BMC Immunology 2012, 13:39 (12 July 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Role of gamma-delta T cells in host response against Staphylococcus aureus-induced pneumonia

Ping Cheng, Tao Liu, Wei-Ying Zhou, Yuan Zhuang, Liu-sheng Peng, Jin-yu Zhang, Zhi-Nan Yin, Xu-hu Mao, Gang Guo, Yun Shi, Quan-ming Zou BMC Immunology 2012, 13:38 (9 July 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Quantile regression for the statistical analysis of immunological data with many non-detects

Paul HC Eilers, Esther Röder, Huub FJ Savelkoul, Roy van Wijk BMC Immunology 2012, 13:37 (7 July 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Adjuvant effect of docetaxel on the immune responses to influenza A H1N1 vaccine in mice

Jian Chen, Lin Yuan, Qing Fan, Fei Su, Yu Chen, Songhua Hu BMC Immunology 2012, 13:36 (7 July 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Plasmacytoid dendritic cell interferon-α production to R-848 stimulation is decreased in male infants

Jennifer P Wang, Lei Zhang, Rachel F Madera, Marcia Woda, Daniel H Libraty BMC Immunology 2012, 13:35 (6 July 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Synthesized OVA323-339MAP octamers mitigate OVA-induced airway inflammation by regulating Foxp3 T regulatory cells

Wen Su, Wenwei Zhong, Yanjie Zhang, Zhenwei Xia BMC Immunology 2012, 13:34 (6 July 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Bacillus anthracis’ lethal toxin induces broad transcriptional responses in human peripheral monocytes

Kassidy M Chauncey, M Lopez, Gurjit Sidhu, Sarah E Szarowicz, Henry V Baker, Conrad Quinn, Frederick S Southwick BMC Immunology 2012, 13:33 (2 July 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Treatment of diabetic mice with undenatured whey protein accelerates the wound healing process by enhancing the expression of MIP-1α, MIP-2, KC, CX3CL1 and TGF-β in wounded tissue

Gamal Badr, Badr M Badr, Mohamed H Mahmoud, Mohamed Mohany, Danny M Rabah, Olivier Garraud BMC Immunology 2012, 13:32 (18 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

TGFβ signaling plays a critical role in promoting alternative macrophage activation

Dapeng Gong, Wei Shi, Sun-ju Yi, Hui Chen, John Groffen, Nora Heisterkamp BMC Immunology 2012, 13:31 (15 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

A novel splice variant of folate receptor 4 predominantly expressed in regulatory T cells

Yi Tian, Guoqiang Wu, Jun-Chao Xing, Jun Tang, Yi Zhang, Ze-Min Huang, Zheng-Cai Jia, Ren Zhao, Zhi-Qiang Tian, Shu-Feng Wang, Xiao-Ling Chen, Li Wang, Yu-Zhang Wu, Bing Ni BMC Immunology 2012, 13:30 (13 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

B7h-expressing dendritic cells and plasma B cells mediate distinct outcomes of ICOS costimulation in T cell-dependent antibody responses

Kevin Larimore, Linda Liang, Sonia Bakkour, William C Sha BMC Immunology 2012, 13:29 (11 June 2012)

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Research article   Open Access

Significance of decoy receptor 3 (Dcr3) and external-signal regulated kinase 1/2 (Erk1/2) in gastric cancer

Donghai Yang, Xin Fan, Ping Yin, Qiang Wen, Feng Yan, Sibo Yuan, Bin Liu, Guohong Zhuang, Zhongchen Liu BMC Immunology 2012, 13:28 (6 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Biodistribution and elimination kinetics of systemic Stx2 by the Stx2A and Stx2B subunit-specific human monoclonal antibodies in mice

Abhineet Sheoran, Kwang-il Jeong, Jean Mukherjee, Anthony Wiffin, Pradeep Singh, Saul Tzipori BMC Immunology 2012, 13:27 (1 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Immune Mediators of protective and pathogenic immune responses in patients with mild and fatal human monocytotropic ehrlichiosis

Nahed Ismail, David H Walker, Purnima Ghose, Yi-Wei Tang BMC Immunology 2012, 13:26 (21 May 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Variation in the IL1B, TNF and IL6 genes and individual susceptibility to prosthetic joint infection

Anna Stahelova, Frantisek Mrazek, Matej Smizansky, Martin Petrek, Jiri Gallo BMC Immunology 2012, 13:25 (8 May 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Innate immune properties of selected human neuropeptides against Moraxella catarrhalis and nontypeable Haemophilus influenzae

Daria Augustyniak, Adam Jankowski, Paweł Mackiewicz, Agnieszka Skowyra, Jan Gutowicz, Zuzanna Drulis-Kawa BMC Immunology 2012, 13:24 (2 May 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Functional requirements for inhibitory signal transmission by the immunomodulatory receptor CD300a

Karen E DeBell, Venkateswara R Simhadri, John L Mariano, Francisco Borrego BMC Immunology 2012, 13:23 (26 April 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Role of CD40 ligation in dendritic cell semimaturation

Anna-Maria Gerlach, Alexander Steimle, Lea Krampen, Alexandra Wittmann, Kerstin Gronbach, Julia Geisel, Ingo B Autenrieth, Julia-Stefanie Frick BMC Immunology 2012, 13:22 (26 April 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Glia maturation factor gamma regulates the migration and adherence of human T lymphocytes

Dustin ND Lippert, John A Wilkins BMC Immunology 2012, 13:21 (18 April 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Tissue transglutaminase treatment leads to concentration-dependent changes in dendritic cell phenotype - implications for the role of transglutaminase in coeliac disease

William J Dalleywater, David YS Chau, Amir M Ghaemmaghami BMC Immunology 2012, 13:20 (16 April 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

High glucose concentrations induce TNF-α production through the down-regulation of CD33 in primary human monocytes

Yolanda Gonzalez, M Teresa Herrera, Gloria Soldevila, Lourdes Garcia-Garcia, Guadalupe Fabián, E Martha Pérez-Armendariz, Karen Bobadilla, Silvia Guzmán-Beltrán, Eduardo Sada, Martha Torres BMC Immunology 2012, 13:19 (14 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Down-regulation of CD33 expression in monocytes from patients with type 2 diabetes may trigger the secretion of TNF-alpha and be indicative of CD33 participation in the inflammatory profile of the disease.

Research article   Open Access Highly Accessed

Understanding mechanisms of vitiligo development in Smyth line of chickens by transcriptomic microarray analysis of evolving autoimmune lesions

Fengying Shi, Byung-Whi Kong, Joon Song, Jeong Lee, Robert L Dienglewicz, Gisela F Erf BMC Immunology 2012, 13:18 (13 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Transcriptomic analysis of the Smyth line chicken model of vitiligo supports the multifactorial etiology of the disorder and highlights a dominant role for the adaptive immune system in melanocyte loss.

Research article   Open Access Highly Accessed

Expression of CD39 on FoxP3+ T regulatory cells correlates with progression of HBV infection

Yan Tang, Li Jiang, Yanhua Zheng, Bing Ni, Yuzhang Wu BMC Immunology 2012, 13:17 (11 April 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Prevalence of collagen VII-specific autoantibodies in patients with autoimmune and inflammatory diseases

Emilia Licarete, Susanne Ganz, Martin J Recknagel, Giovanni Di Zenzo, Takashi Hashimoto, Michael Hertl, Giovanna Zambruno, Gheorghe Hundorfean, Jonas Mudter, Markus F Neurath, Leena Bruckner-Tuderman, Cassian Sitaru BMC Immunology 2012, 13:16 (4 April 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

The Tat protein of human immunodeficiency virus-1 enhances hepatitis C virus replication through interferon gamma-inducible protein-10

Jing Qu, Qi Zhang, Youxing Li, Weiyong Liu, Lvxiao Chen, Ying Zhu, Jianguo Wu BMC Immunology 2012, 13:15 (3 April 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Association between COX-2 rs2745557 polymorphism and prostate cancer risk: a systematic review and meta-analysis

Hongtuan Zhang, Yong Xu, Zhihong Zhang, Ranlu Liu, Baojie Ma BMC Immunology 2012, 13:14 (21 March 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Potential T cell epitopes of Mycobacterium tuberculosis that can instigate molecular mimicry against host: implications in autoimmune pathogenesis

Sathi Babu Chodisetti, Pradeep K Rai, Uthaman Gowthaman, Susanta Pahari, Javed N Agrewala BMC Immunology 2012, 13:13 (21 March 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling

Ruben L Smeets, Wilco WM Fleuren, Xuehui He, Paul M Vink, Frank Wijnands, Monika Gorecka, Henri Klop, Sussane Bauerschmidt, Anja Garritsen, Hans JPM Koenen, Irma Joosten, Annemieke MH Boots, Wynand Alkema BMC Immunology 2012, 13:12 (14 March 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Increased levels of prolactin receptor expression correlate with the early onset of lupus symptoms and increased numbers of transitional-1 B cells after prolactin treatment

Yadira Ledesma-Soto, Francisco Blanco-Favela, Ezequiel M Fuentes-Pananá, Emiliano Tesoro-Cruz, Rafael Hernández-González, Lourdes Arriaga-Pizano, María V Legorreta-Haquet, Eduardo Montoya-Diaz, Luis Chávez-Sánchez, María E Castro-Mussot, Adriana K Chávez-Rueda BMC Immunology 2012, 13:11 (9 March 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Influence of variable domain glycosylation on anti-neutrophil cytoplasmic autoantibodies and anti-glomerular basement membrane autoantibodies

Peng-Cheng Xu, Shen-Ju Gou, Xiao-Wei Yang, Zhao Cui, Xiao-Yu Jia, Min Chen, Ming-Hui Zhao BMC Immunology 2012, 13:10 (9 March 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

IL-10 transcription is negatively regulated by BAF180, a component of the SWI/SNF chromatin remodeling enzyme

Andrea L Wurster, Patricia Precht, Kevin G Becker, William H Wood, Yongqing Zhang, Zhong Wang, Michael J Pazin BMC Immunology 2012, 13:9 (15 February 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Age-related accumulation of T cells with markers of relatively stronger autoreactivity leads to functional erosion of T cells

Zohreh Tatari-Calderone, Milica Stojakovic, Ramita Dewan, Gama Le Bouder, Dragana Jankovic, Stanislav Vukmanovic BMC Immunology 2012, 13:8 (9 February 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Cervical cancer cell lines expressing NKG2D-ligands are able to down-modulate the NKG2D receptor on NKL cells with functional implications

Miriam I Jimenez-Perez, Luis F Jave-Suarez, Pablo C Ortiz-Lazareno, Alejandro Bravo-Cuellar, Oscar Gonzalez-Ramella, Adriana Aguilar-Lemarroy, Georgina Hernandez-Flores, Ana L Pereira-Suarez, Adrian Daneri-Navarro, Susana del Toro-Arreola BMC Immunology 2012, 13:7 (8 February 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation

Andrew Q Ford, Preeta Dasgupta, Irina Mikhailenko, Elizabeth MP Smith, Nancy Noben-Trauth, Achsah D Keegan BMC Immunology 2012, 13:6 (31 January 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Transfer of macrophages expressing IL-4 receptor alpha into a mouse model of allergic lung inflammation is sufficient to enhance TH2-driven eosinophilic inflammation and may represent a suitable target to reduce exacerbations in asthma patients.

Research article   Open Access

Intermittent preventive treatment with sulfadoxine-pyrimethamine does not modify plasma cytokines and chemokines or intracellular cytokine responses to Plasmodium falciparum in Mozambican Children

Diana Quelhas, Laura Puyol, Llorenç Quintó, Tacilta Nhampossa, Elisa Serra-Casas, Eusébio Macete, Pedro Aide, Sergi Sanz, John J Aponte, Denise L Doolan, Pedro L Alonso, Clara Menéndez, Carlota Dobaño BMC Immunology 2012, 13:5 (26 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Micrurus snake venoms activate human complement system and generate anaphylatoxins

Gabriela D Tanaka, Giselle Pidde-Queiroz, Maria de Fátima D Furtado, Carmen van den Berg, Denise V Tambourgi BMC Immunology 2012, 13:4 (16 January 2012)

Abstract | Full text | PDF | PubMed

Retraction   Open Access

Retraction: The absence of MyD88 has no effect on the induction of alternatively activated macrophage during Fasciola hepatica infection

HongLin Luo, Weiyi Huang, Dongying Wang, Haoju Wang, Kui Nie BMC Immunology 2012, 13:3 (16 January 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

A selective and potent CXCR3 antagonist SCH 546738 attenuates the development of autoimmune diseases and delays graft rejection

Chung-Her Jenh, Mary Ann Cox, Long Cui, Eva-Pia Reich, Lee Sullivan, Shu-Cheng Chen, David Kinsley, Shiguang Qian, Seong Heon Kim, Stuart Rosenblum, Joseph Kozlowski, Jay S Fine, Paul J Zavodny, Daniel Lundell BMC Immunology 2012, 13:2 (10 January 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Acute sleep deprivation has no lasting effects on the human antibody titer response following a novel influenza A H1N1 virus vaccination

Christian Benedict, Maria Brytting, Agneta Markström, Jan-Erik Broman, Helgi Schiöth BMC Immunology 2012, 13:1 (4 January 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Neuroantigen-specific, tolerogenic vaccines: GM-CSF is a fusion partner that facilitates tolerance rather than immunity to dominant self-epitopes of myelin in murine models of experimental autoimmune encephalomyelitis (EAE)

Derek J Abbott, J Lori Blanchfield, David A Martinson, Sean C Russell, Najla Taslim, Alan D Curtis, Mark D Mannie BMC Immunology 2011, 12:72 (30 December 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

B Lymphocyte intestinal homing in inflammatory bowel disease

Caterina Defendenti, Piercarlo Sarzi-Puttini, Silvia Grosso, Annamaria Croce, Olivia Senesi, Simone Saibeni, Simona Bollani, Piero Almasio, Savino Bruno, Fabiola Atzeni BMC Immunology 2011, 12:71 (30 December 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Selectively enhanced expression of prophenoloxidase activating enzyme 1 (PPAE1) at a bacteria clearance site in the white shrimp, Litopenaeus vannamei

In-Kwon Jang, Zhenguo Pang, Jiaping Yu, Su-Kyoung Kim, Hyung-Cheol Seo, Yeong-Rok Cho BMC Immunology 2011, 12:70 (30 December 2011)

Abstract | Full text | PDF | PubMed

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