BMC Immunology is calling for submissions to our Collection on Cellular immunology and HIV.
HIV (Human Immunodeficiency Virus) attacks and weakens the immune system, specifically by invading immune cells such as CD4+ T cells. This invasion of immune cells leads to a progressive decline in the immune system's ability to effectively respond to infection, eventually resulting in Acquired Immunodeficiency Syndrome (AIDS).
HIV continues to be a major challenge to global public health, with 40 million people estimated to be living with HIV in 2021, and 1.5 million new infections estimated in the same year. However, while strategies for managing outcomes for people living with HIV have been established, there is no cure. Treating HIV is a challenge because the immune system becomes ineffective at controlling infection and preventing disease progression. HIV is also particularly adept at immune evasion, by establishing latent reservoirs that are not detected during infection, but can eventually reactivate and replicate.
In response, the United Nations’ Sustainable Development Goal (SDG) Target 3.3: Communicable Diseases, resolves to end the HIV epidemic by 2030. In support of this objective, BMC Immunology is pleased to announce a new Collection, Cellular immunology and HIV, which will collate molecular and cellular research that improves our understanding of the underlying mechanisms of HIV and the host immune response.
We welcome submissions exploring the following areas of research:
- Cellular immune responses and regulation in response to HIV infection
- The interactions of HIV with different immune cell subsets
- Mechanisms of HIV evasion from immune surveillance
- HIV latency and reservoirs
- The role of immune checkpoints in HIV immunopathogenesis
- Immunological memory in HIV infection
- The effect of co-infection on cellular immune responses
- Mechanisms of immune reconstitution and the recovery of cellular immunity following antiretroviral therapy and immune-based therapy
- Therapeutic approaches for targeting cellular immune responses for HIV prevention and control
- Cellular responses to vaccines and strategies for vaccine development
This Collection supports SDG 3: Good Health and Wellbeing.
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