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BMC Immunology

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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Hans Zauner


Welcome to BMC Immunology published by BioMed Central
BMC Immunology is an open access journal publishing original peer-reviewed research articles in molecular, cellular, tissue-level, organismal, functional, and developmental aspects of the immune system. BMC Immunology (ISSN 1471-2172) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.



BMC Featured articles

Image credit: Wikipedia
BMC Immunology 2009, 10:26
The bacterial pathogen Coxiella burnetti normally infects human dendritic cells silently, but provokes their FcR-dependent stimulation if coated with antibodies, while transferring such antibodies to mice affords protection against infection, even in mice deficient in either Fc receptors or complement.
Credit: Adapted from Colja Venturini et al. BMC Immunology
BMC Immunology 2009, 10:16
Anti-idiotypic antibodies that bind the antigen-combining site of a monoclonal antibody specific for the pathological isoform of the prion protein (PrPSc) may themselves resemble PrPSc, opening new avenues for the study and treatment of prion disease.


BMC  Latest articles published in BMC Immunology        [more info]


Research article
Conserved cryptic recombination signals in Vkappa gene segments are cleaved in small pre-B cells
Anne E. Lieberman, Masayuki Kuraoka, Marco Davila, Garnett Kelsoe, Lindsay G. Cowell
BMC Immunology 2009, 10:37 (25June2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
The expression of the -defensins hBD-2 and hBD-3 is differentially regulated by NF-B and MAPK/AP-1 pathways in an in vitro model of Candida esophagitis
Nadine Steubesand, Karlheinz Kiehne, Gabriele Brunke, Rene Pahl, Karina Reiss, Karl-Heinz Herzig, Sabine Schubert, Stefan Schreiber, Ulrich R Flsch, Philip Rosenstiel, Alexander Arlt
BMC Immunology 2009, 10:36 (12June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Toll-like receptors, chemokine receptors and death receptor ligands responses in SARS coronavirus infected human monocyte derived dendritic cells
Helen KW Law, Chung Yan Cheung, Sin Fun Sia, Yuk On Chan, JS Malik Peiris, Yu Lung Lau
BMC Immunology 2009, 10:35 (8June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Increased levels of soluble CD226 in sera accompanied by decreased membrane CD226 expression on peripheral blood mononuclear cells from cancer patients
Zhuwei Xu, Tao Zhang, Ran Zhuang, Yun Zhang, Wei Jia, Chaojun Song, Kun Yang, Angang Yang, Boquan Jin
BMC Immunology 2009, 10:34 (2June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice
Kathryn A Niese, Ann R Collier, Amanda R Hajek, Stephen D Cederbaum, William E O'Brien, Marsha Wills-Karp, Marc E Rothenberg, Nives Zimmermann
BMC Immunology 2009, 10:33 (1June2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Different levels of humoral immunoreactivity to different wheat cultivars gliadin are present in patients with celiac disease and in patients with multiple myeloma
Aleksandra Konic-Ristic, Dejan Dodig, Radmilo Krstic, Svetislav Jelic, Ivan Stankovic, Aleksandra Ninkovic, Jelena Radic, Irina Besu, Branka Bonaci-Nikolic, Njegica Jojic, Milica Djordjevic, Dragan Popovic, Zorica Juranic
BMC Immunology 2009, 10:32 (31May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
High-sensitive and rapid detection of Mycobacterium tuberculosis infection by IFN- release assay among HIV-infected individuals in BCG-vaccinated area
Weimin Jiang, Lingyun Shao, Ying Zhang, Shu Zhang, Chengyan Meng, Yunya Xu, Lingli Huang, Yun Wang, Ying Wang, Xinhua Weng, Wenhong Zhang
BMC Immunology 2009, 10:31 (28May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Methodology article
Efficient isolation of highly purified tonsil B lymphocytes using RosetteSep with allogeneic human red blood cells
Jonathan Zuccolo, Tammy L Unruh, Julie P Deans
BMC Immunology 2009, 10:30 (27May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
T cells cooperate with palmitic acid in induction of beta cell apoptosis
Tamara Cvjetianin, Ivana Stojanovi, Gordana Timotijevi, Stanislava Stoi-Grujii, Djordje Miljkovi
BMC Immunology 2009, 10:29 (22May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
A kinase-dead knock-in mutation in mTOR leads to early embryonic lethality and is dispensable for the immune system in heterozygous mice
Boris Shor, Druie Cavender, Crafford Harris
BMC Immunology 2009, 10:28 (20May2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research
Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro
Xiao-Yun Fan, Arjen van den Berg, Mieke Snoek, Laurens van der Flier, Barbara Smids, Henk M Jansen, Rong-Yu Liu, Rene Lutter
Respiratory Research 2009, 10:62 (3July2009)
[Abstract] [Provisional PDF]

Review
Does unrestrained single-chamber plethysmography provide a valid assessment of airway responsiveness in allergic BALB/c mice?
Qingling Zhang, Kefang Lai, Jiaxing Xie, Guoqin Chen, Nanshan Zhong
Respiratory Research 2009, 10:61 (3July2009)
[Abstract] [Provisional PDF]

Research article
Use of a T cell interferon gamma release assay in the investigation for suspected active tuberculosis in a low prevalence area
Niclas Winqvist, Per Bjorkman, Ann Noren, Hakan Miorner
BMC Infectious Diseases 2009, 9:105 (3July2009)
[Abstract] [Provisional PDF]

Research
Evolution of SIV toward RANTES resistance in macaques rapidly progressing to AIDS upon coinfection with HHV-6A
Angelique Biancotto, Jean-Charles Grivel, Andrea Lisco, Christophe Vanpouille, Phillip D. Markham, Robert C. Gallo, Leonid B. Margolis, Paolo Lusso
Retrovirology 2009, 6:61 (2July2009)
[Abstract] [Provisional PDF]

Research
CSF/serum quotient graphs for the evaluation of intrathecal C4 synthesis
Barbara Padilla-Docal, Alberto J Dorta-Contreras, Raisa Bu-Coifiu-Fanego, Alexis Rodriguez-Rey
Cerebrospinal Fluid Research 2009, 6:8 (2July2009)
[Abstract] [Provisional PDF]

Research article
Apoptotic cell-mediated suppression of streptococcal cell wall-induced arthritis is associated with alteration of macrophage function and local regulatory T cell increase: a potential cell-based therapy?
Sylvain Perruche, Philippe Saas, Wan Jun Chen
Arthritis Research & Therapy 2009, 11:R104 (1July2009)
[Abstract] [Provisional PDF]

Research
Reduction of the HIV-1 reservoir in resting CD4+ T-lymphocytes by high dosage intravenous immunoglobulin treatment: a proof-of-concept study
Annica Lindkvist, Arvid Eden, Melissa M Norstrom, Veronica D Gonzalez, Staffan Nilsson, Bo Svennerholm, Annika C Karlsson, Johan K Sandberg, Anders Sonnerborg, Magnus Gisslen
AIDS Research and Therapy 2009, 6:15 (1July2009)
[Abstract] [Provisional PDF]

Research article
Clinical impact of B-cell depletion with the anti-CD20 antibody rituximab in chronic fatigue syndrome: a preliminary case series
Oystein Fluge, Olav Mella
BMC Neurology 2009, 9:28 (1July2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Review
Differences in resistance mutations among HIV-1 non-subtype B infections : a systematic review of evidence (1996-2008)
Jorge L Martinez-Cajas, Nitika P Pai, Marina B Klein, Mark A Wainberg
Journal of the International AIDS Society 2009, 12:11 (30June2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Isolation of a human-like antibody fragment (scFv) that neutralizes ricin biological activity
Thibaut Pelat, Michael Hust, Martha Hale, Marie-Paule Lefranc, Stefan Dubel, Philippe Thullier
BMC Biotechnology 2009, 9:60 (30June2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

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