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- Allan Lau, The University of Hong Kong
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- Juan Carlos Zuniga-Pflucker, University of Toronto
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Articles
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BMC Immunology 2011, 12:60Signalling pathways in lung inflammation
CD4+ T helper cells primed in vivo induce an allergic lung reaction in an asthma model in mice, partly through pathways dependent on the cytokine IL4α receptor and the transcription factor STAT6.
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BMC Immunology 2011, 12:57Role of DC-STAMP in cytokine production
Bone marrow-derived dendritic cells (DCs) lacking DC-STAMP, a multi-membrane spanning protein preferentially expressed by these cells, secrete less cytokines and show impaired T cell activation potential and induction of Th1 responses in response to lipopolysaccharide maturation.
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BMC Immunology 2011, 12:55Alcohol impairs immune response
Acute and prolonged alcohol use has a profound inhibitory effect on Type I Interferon (IFN) induction regardless of intracellular or cell surface-derived danger signals and impairs Type I IFN responses to viral or bacterial pathogen-derived signals.
Hot topic
BMC Immunology 2011, 12:67 (15 December 2011)
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BMC Immunology is an open access, peer-reviewed journal that considers articles on molecular, cellular, tissue-level, organismal, functional, and developmental aspects of the immune system.
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Semel Institute for Neuroscience & Human Behavior,
UCLA David Geffen School of Medicine, USA
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