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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD


Welcome to BMC Immunology published by BioMed Central
BMC Immunology is an open access journal publishing original peer-reviewed research articles in all aspects of cellular, tissue-level, organismal, functional, and developmental aspects of the immune system. BMC Immunology (ISSN 1471-2172) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Scientific (ISI) and Google Scholar.



BMC Featured articles

Credit: Tommaso Leonardi, from wikipedia, Public Domain
BMC Immunology 2008, 9:14
DMSO-differentiated human PLB-985 cells share morphological, cellular and physiological similarities with neutrophils, allowing them to be used as an easily transfectable model for the study of neutrophil signaling pathways.

Image credit: Acute leukaemia on Wikipedia, GNU FDL
BMC Immunology 2007, 8:28
Single nucleotide polymorphisms in the Fas and Caspase-10 genes, when each inherited from a different parent, can have an additive effect and lead to the development of autoimmune lymphoproliferative syndrome in patients with healthy parents.



BMC  Latest articles published in BMC Immunology        [more info]


Research article
Birth season and environmental influences on blood leucocyte and lymphocyte subpopulations in rural Gambian infants
Andrew C Collinson, Pa Tamba Ngom, Sophie E Moore, Gareth Morgan, Andrew M Prentice
BMC Immunology 2008, 9:18 (7May2008)
[Abstract] [Provisional PDF]

Research article
Stimulatory effect of Eucalyptus essential oil on innate cell-mediated immune response
Annalucia Serafino, Paola Sinibaldi Vallebona, Federica Andreola, Manuela Zonfrillo, Luana Mercuri, Memmo Federici, Guido Rasi, Enrico Garaci, Pasquale Pierimarchi
BMC Immunology 2008, 9:17 (18April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Retinoic Acid Receptor-alpha mediates human T-cell activation and Th2 cytokine production
Harry D Dawson, Gary Collins, Robert Pyle, Michael Key, Dennis D Taub
BMC Immunology 2008, 9:16 (16April2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Dendritic Cells are preferentially targeted among hematolymphocytes by Modified Vaccinia Virus Ankara and play a key role in the induction of virus-specific T cell responses in vivo
Luzheng Liu, Rahul Chavan, Mark B Feinberg
BMC Immunology 2008, 9:15 (15April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Methodology article
Cytokine generation, promoter activation, and oxidant-independent NF-B activation in a transfectable human neutrophilic cellular model
Thornin Ear, Patrick P McDonald
BMC Immunology 2008, 9:14 (11April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Coexpression of GM-CSF and antigen in DNA prime-adenoviral vector boost immunization enhances polyfunctional CD8+ T cell responses, whereas expression of GM-CSF antigen fusion protein induces autoimmunity
Matthias Tenbusch, Seraphin Kuate, Bettina Tippler, Nicole Gerlach, Simone Schimmer, Ulf Dittmer, Klaus berla
BMC Immunology 2008, 9:13 (11April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Immunomodulation of human monocytes following exposure to Lutzomyia intermedia saliva
Maria Jos Menezes, Dirceu J Costa, Jorge Clarncio, Jos Carlos Miranda, Aldina Barral, Manoel Barral-Netto, Cludia Brodskyn, Camila I de Oliveira
BMC Immunology 2008, 9:12 (10April2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections
Reece G Marillier, Chesney Michels, Elizabeth M Smith, Lizette CE Fick, Mosiuoa Leeto, Benjamin Dewals, William GC Horsnell, Frank Brombacher
BMC Immunology 2008, 9:11 (28March2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Activation of tonsil dendritic cells with immuno-adjuvants
Marta E Polak, Nicola J Borthwick, Francis G Gabriel, Martine J Jager, Ian A Cree
BMC Immunology 2008, 9:10 (18March2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Methodology article
Precision and linearity targets for validation of an IFN ELISPOT, cytokine flow cytometry, and tetramer assay using CMV peptides
Holden T Maecker, Jeffrey Hassler, Janice K Payne, Amanda Summers, Karrie Comatas, Manar Ghanayem, Michael A Morse, Timothy M Clay, Herbert K Lyerly, Sonny Bhatia, Smita A Ghanekar, Vernon C Maino, Corazon delaRosa, Mary L Disis
BMC Immunology 2008, 9:9 (17March2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research article
Autoantibodies as potential biomarkers for breast cancer
Li Zhong, Kun Ge, Jin-chi Zu, Long-hua Zhao, Wei-ke Shen, Jian-fei Wang, Xiao-gang Zhang, Xu Gao, Wanping Hu, Yun Yen, Kemp H Kernstine
Breast Cancer Research 2008, 10:R40 (6May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research
The pregnancy-associated glycoprotein-hormones activin A and inhibin A interfere with dendritic cell maturation
Sabine E Segerer, Nora Mueller, Jens van den Brandt, Michaela Kapp, Johannes Dietl, Holger M Reichardt, Lorenz Rieger, Ulrike Kammerer
Reproductive Biology and Endocrinology 2008, 6:17 (6May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Immune correlates of CD4 decline in HIV-infected patients experiencing virologic failure before undergoing treatment interruption
Kenneth H Huang, Mona R Loutfy, Christos M Tsoukas, Nicole F Bernard
BMC Infectious Diseases 2008, 8:59 (2May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Molecular discrimination of responders and non-responders to anti-TNF-alpha therapy in rheumatoid arthritis by etanercept
Dirk Koczan, Susanne Drynda, Michael Hecker, Andreas Drynda, Reinhard Guthke, Joern Kekow, Hans-Juergen Thiesen
Arthritis Research & Therapy 2008, 10:R50 (2May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research
Characterization of immortalized MARCO and SR-AI/II-deficient murine alveolar macrophage cell lines
Hongwei Zhou, Amy Imrich, Lester Kobzik
Particle and Fibre Toxicology 2008, 5:7 (2May2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Experimental manipulation of immune-mediated disease and its fitness costs for rodent malaria parasites
Grainne H Long, Brian H K Chan, Judith E Allen, Andrew F Read, Andrea L Graham
BMC Evolutionary Biology 2008, 8:128 (30April2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Primary research
Lack of c-kit receptor promotes mammary tumors in N-nitrosomethylurea-treated Ws/Ws rats
Maricel V. Maffini, Ana M. Soto, Carlos Sonnenschein, Nikoletta Papadopoulos, Theoharis C. Theoharides
Cancer Cell International 2008, 8:5 (29April2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research
Expression Analysis of G Protein-Coupled Receptors in Mouse Macrophages
Jane E Lattin, Kate Schroder, Andrew I Su, John R Walker, Jie Zhang, Tim Wiltshire, Kaoru Saijo, Christopher K Glass, David A Hume, Stuart Kellie, Matthew J Sweet
Immunome Research 2008, 4:5 (29April2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Short report
Imbalanced effector and regulatory cytokine responses may underlie mycobacterial immune restoration disease
Andrew Lim, Lloyd D'Orsogna, Patricia Price, Martyn A French
AIDS Research and Therapy 2008, 5:9 (29April2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Software review
The Multiscale Systems Immunology project: software for cell-based immunological simulation
Faheem Mitha, Timothy A. Lucas, Feng Feng, Thomas B. Kepler, Cliburn Chan
Source Code for Biology and Medicine 2008, 3:6 (28April2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

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