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Editor-in-Chief Melissa Norton, MD
Medical Editor Jigisha Patel, MRCP PhD
In-house Editor Iratxe Puebla
Welcome to BMC Cancer published by BioMed Central
BMC Cancer is an open access journal publishing original peer-reviewed research articles in all aspects of research relating to cancer, including molecular biology,
genetics, pathophysiology, epidemiology, clinical reports, and controlled trials.
BMC Cancer (ISSN 1471-2407) is indexed/tracked/covered by PubMed, MEDLINE, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Cancer 2008, 8 :203
In the general population, a family history of breast cancer is a poor predictor for early onset of the disease, indicating that use of family history as the sole screening criterion will result in unnecessary testing.
BMC Cancer 2008, 8 :183
Although recurrent urothelial tumors are unlikely to originate directly from the initial lesion, genome and transcriptome profiling suggests that the gene expression profile is established early in their development and maintained in subsequent tumors.
BMC Cancer 2008, 8 :174
The human pregnane X receptor and retinoid X receptor alpha show nuclear localization in recurrent breast cancer tissues, suggesting that their heterodimers might be involved in cancer progression and resistance to endocrine therapies.
BMC Cancer 2008, 8 :173
BAC array analysis of chromosome 11 status on both primary tumors and cell ines and meta-analysis of expression profiles of 692 neuroblastoma samples suggest that CADM1 is a potential neuroblastoma suppressor gene.
BMC Cancer 2008, 8 :155
Counselling about the risks of breast and ovarian cancer for women who carry a BRCA1 or BRCA2 mutation should take into account the family history, because these women have a higher risk of cancer than the average population risk indicates.
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Research article
Paclitaxel loading in PLGA nanospheres affected
the in vitro drug cell accumulation and antiproliferative activity Luisa Vicari, Teresa Musumeci, Ignazio Giannone, Luana Adamo, Concetta Conticello, Ruggero De Maria, Rosario Pignatello, Giovanni Puglisi, Massimo Gulisano BMC Cancer 2008, 8 :212 (25 [Abstract ] [Provisional PDF ]
Research article
Predictors of Persistent Cytologic Abnormalities after treatment of Cervical intraepithelial Neoplasia in Soweto, South Africa: A Cohort study in a HIV High Prevalence Population. Yasmin Adam, Cyril J van Gelderen, Guy de Bruyn, James A McIntyre, Diane A Turton, Neil A Martinson BMC Cancer 2008, 8 :211 (25 [Abstract ] [Provisional PDF ]
Research article
Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer Hiroshi Makino, Hiroyuki Uetake, Kathleen Danenberg, Peter V Danenberg, Kenichi Sugihara BMC Cancer 2008, 8 :210 (25 [Abstract ] [Provisional PDF ]
Research article
Vinorelbine-based salvage therapy in HER2-positive metastatic breast cancer patients progressing during trastuzumab-containing regimens: a retrospective study Filippo Montemurro, Stefania Redana, Franco Nole, Michela Donadio, Maria Elena Jacomuzzi, Giorgio Valabrega, Giuseppe Viale, Anna Sapino, Massimo Aglietta BMC Cancer 2008, 8 :209 (24 [Abstract ] [Provisional PDF ]
Research article
Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue Li-Shu Wang, Yi-Wen Huang, Suling Liu, Pearlly Yan, Young C Lin BMC Cancer 2008, 8 :208 (24 [Abstract ] [Provisional PDF ]
Study protocol
ProsCan for Men: Randomised controlled trial of a decision support intervention for men with localised prostate cancer Suzanne K Chambers, Megan Ferguson, R A Gardiner, David Nicol, Louisa Gordon, Stefano Occhipinti, Joanne Aitken BMC Cancer 2008, 8 :207 (24 [Abstract ] [Provisional PDF ]
Research article
ENMD-1198, a novel tubulin-binding agent reduces HIF-1 and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo Christian Moser, Sven A Lang, Akira Mori, Claus Hellerbrand, Hans J Schlitt, Edward K Geissler, William E Fogler, Oliver Stoeltzing BMC Cancer 2008, 8 :206 (23 [Abstract ] [Provisional PDF ]
Research article
Underexpression of Deleted in liver cancer 2 (DLC2) is associated with overexpression of RhoA and poor prognosis in hepatocellular carcinoma Li Xiaorong, Wu Wei, Qian Liyuan, Yang Kaiyan BMC Cancer 2008, 8 :205 (23 [Abstract ] [Provisional PDF ]
Research article
p53 expression is significantly correlated with high risk of malignancy and epithelioid differentiation in gastrointestinal stromal tumors. An immunohistochemical study with 104 GISTs. Ursula Pauser, Nina Schmedt auf der Gunne, Gunter Kloppel, Hartmut Merz, Alfred C Feller BMC Cancer 2008, 8 :204 (23 [Abstract ] [Provisional PDF ]
Research article
A family history of breast cancer will not predict female early onset breast cancer in a population-based setting Geertruida H De Bock, Catharina E Jacobi, Caroline Seynaeve, Elly M.M. Krol-Warmerdam, Jannet Blom, Christi J. Van Asperen, Cees J. Cornelisse, Jan G.M. Klijn, Peter Devilee, Rob A.E.M. Tollenaar, Cecile T.M Brekelmans, Johannes C. Van Houwelingen BMC Cancer 2008, 8 :203 (23 [Abstract ] [Provisional PDF ]
Review
Histological variants of cutaneous Kaposi sarcoma Liron Pantanowitz, Wayne Grayson Diagnostic Pathology 2008, 3 :31 (25 [Abstract ] [Provisional PDF ]
Research
Approaches to interim analysis of cancer randomised clinical trials with time to event endpoints: a survey from the Italian National Monitoring Centre for Clinical Trials. Irene Floriani, Nicole Rotmensz, Elena Albertazzi, Valter Torri, Marisa De Rosa, Carlo Tomino, Filippo de Braud Trials 2008, 9 :46 (25 [Abstract ] [Provisional PDF ]
Case report
Tongue metastasis as an initial presentation of renal cell carcinoma: a case report and literature review Faisal Azam, Muneer Abubakerr, Simon Gollins Journal of Medical Case Reports 2008, 2 :249 (25 [Abstract ] [Provisional PDF ]
Case report
Sclerosing epithelioid fibrosarcoma as a rare cause of ascites in a young man: a case report Philip J Smith, Beverley Almeida, Jasna Krajacevic, Barry Taylor Journal of Medical Case Reports 2008, 2 :248 (25 [Abstract ] [Provisional PDF ]
Case report
Gastric metastases originating from occult breast lobular carcinoma: Diagnostic and therapeutic problems Antonio Ciulla, Gioacchino Castronovo, Giovanni Tomasello, Alfonso Maurizio Maiorana, Leila Russo, Elio Daniele, Gaspare Genova World Journal of Surgical Oncology 2008, 6 :78 (25 [Abstract ] [Provisional PDF ]
Research
Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery Nathalie Scholler, Jennifer A Gross, Barbara Garvik, Lance Wells, Yan Liu, Christian M Loch, Arturo B Ramirez, Martin M McIntosh, Paul D Lampe, Nicole Urban Journal of Translational Medicine 2008, 6 :41 (24 [Abstract ] [Provisional PDF ]
Research article
Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer Henna Heinonen, Anni Nieminen, Matti Saarela, Anne Kallioniemi, Juha Klefstrom, Sampsa Hautaniemi, Outi Monni BMC Genomics 2008, 9 :348 (24 [Abstract ] [Provisional PDF ]
Review
Apoptotic pathways in pancreatic ductal adenocarcinoma Rainer Hamacher, Roland M Schmid, Dieter Saur, Gunter Schneider Molecular Cancer 2008, 7 :64 (24 [Abstract ] [Provisional PDF ]
Case report
Metastatic gastric cancer presenting with shoulder-hand syndrome: a case report Marco Massarotti, Gianluigi Ciocia, Roberto Ceriani, Arturo Chiti, Bianca Marasini Journal of Medical Case Reports 2008, 2 :240 (24 [Abstract ] [Provisional PDF ]
Research article
Critical evaluation of HPV16 gene copy number quantification by SYBR green PCR Ian Roberts, Grace Ng, Nicola Foster, Margaret Stanely, Michael T Herdman, Mark R Pett, Andrew Teschendorff, Nicholas Coleman BMC Biotechnology 2008, 8 :57 (24 [Abstract ] [Provisional PDF ]
Featured articles 
