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Cell and molecular biology

This section covers all aspects of tumor biology from a molecular and cellular point of view. Topics of interest include, but are not limited to, animal models, hypoxia, angiogenesis, metastasis, cellular signaling, cancer stem cells, DNA damage and repair, cell cycle and apoptosis.

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51.

Research article   Open Access Highly Accessed

miR-17-5p targets the p300/CBP-associated factor and modulates androgen receptor transcriptional activity in cultured prostate cancer cells

Ai-Yu Gong, Alex N Eischeid, Jing Xiao, Jian Zhao, Dongqing Chen, Zhao-Yi Wang, Charles YF Young, Xian-Ming Chen BMC Cancer 2012, 12:492 (24 October 2012)

Abstract | Full text | PDF | PubMed

52.

Research article   Open Access Highly Accessed

Wnt5a promotes ewing sarcoma cell migration through upregulating CXCR4 expression

Zhe Jin, Chenghai Zhao, Xiaorui Han, Yaxin Han BMC Cancer 2012, 12:480 (18 October 2012)

Abstract | Full text | PDF | PubMed

53.

Research article   Open Access Highly Accessed

Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells

Masato Eitaki, Tohru Yamamori, Shunsuke Meike, Hironobu Yasui, Osamu Inanami BMC Cancer 2012, 12:469 (12 October 2012)

Abstract | Full text | PDF | PubMed

54.

Research article   Open Access Highly Accessed

Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitro

Thorsten Lieke, Wolf Ramackers, Sabine Bergmann, Jürgen Klempnauer, Michael Winkler, Johannes Klose BMC Cancer 2012, 12:466 (11 October 2012)

Abstract | Full text | PDF | PubMed

55.

Research article   Open Access

Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis

Jie Chen, Dehuan Shi, Xiaoyan Liu, Shuang Fang, Jie Zhang, Yueran Zhao BMC Cancer 2012, 12:464 (10 October 2012)

Abstract | Full text | PDF | PubMed

56.

Research article   Open Access

Activation of AKT by hypoxia: a potential target for hypoxic tumors of the head and neck

Hanneke Stegeman, Johannes H Kaanders, Deric L Wheeler, Albert J van der Kogel, Marieke M Verheijen, Stijn J Waaijer, Mari Iida, Reidar Grénman, Paul N Span, Johan Bussink BMC Cancer 2012, 12:463 (10 October 2012)

Abstract | Full text | PDF | PubMed

57.

Research article   Open Access Highly Accessed

Correlation between Slug transcription factor and miR-221 in MDA-MB-231 breast cancer cells

Elisabetta Lambertini, Andrea Lolli, Federica Vezzali, Letizia Penolazzi, Roberto Gambari, Roberta Piva BMC Cancer 2012, 12:445 (2 October 2012)

Abstract | Full text | PDF | PubMed

58.

Research article   Open Access Highly Accessed

Hypoxic enhancement of exosome release by breast cancer cells

Hamish W King, Michael Z Michael, Jonathan M Gleadle BMC Cancer 2012, 12:421 (24 September 2012)

Abstract | Full text | PDF | PubMed

59.

Research article   Open Access Highly Accessed

Mechanistic studies of Gemcitabine-loaded nanoplatforms in resistant pancreatic cancer cells

Anne-Laure Papa, Sudipta Basu, Poulomi Sengupta, Deboshri Banerjee, Shiladitya Sengupta, Rania Harfouche BMC Cancer 2012, 12:419 (22 September 2012)

Abstract | Full text | PDF | PubMed

60.

Research article   Open Access Highly Accessed

Simultaneous modulation of the intrinsic and extrinsic pathways by simvastatin in mediating prostate cancer cell apoptosis

Anna Goc, Samith T Kochuparambil, Belal Al-Husein, Ahmad Al-Azayzih, Shuaib Mohammad, Payaningal R Somanath BMC Cancer 2012, 12:409 (14 September 2012)

Abstract | Full text | PDF | PubMed

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