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1.

9288
Accesses

Software   Open Access Highly Accessed

An electronic application for rapidly calculating Charlson comorbidity score

William H Hall, Ramanathan Ramachandran, Samir Narayan, Ashesh B Jani, Srinivasan Vijayakumar BMC Cancer 2004, 4:94 (20 December 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

2.

9268
Accesses

Research article   Open Access Highly Accessed

Does colon cancer ever metastasize to bone first? a temporal analysis of colorectal cancer progression

Eira S Roth, David T Fetzer, Bruce J Barron, Usha A Joseph, Isis W Gayed, David Q Wan BMC Cancer 2009, 9:274 (7 August 2009)

Abstract | Full text | PDF | PubMed

3.

9176
Accesses

Research article   Open Access Highly Accessed

Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment

Peter A Fasching, Katharina Heusinger, Lothar Haeberle, Melitta Niklos, Alexander Hein, Christian M Bayer, Claudia Rauh, Ruediger Schulz-Wendtland, Mayada R Bani, Michael Schrauder, Laura Kahmann, Michael P Lux, Johanna D Strehl, Arndt Hartmann, Arno Dimmler, Matthias W Beckmann, David L Wachter BMC Cancer 2011, 11:486 (14 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

4.

7413
Accesses

Research article   Open Access Highly Accessed

Atypical glandular cells in conventional cervical smears: Incidence and follow-up

René Scheiden, Catherine Wagener, Ulrich Knolle, Walter Dippel, Catherine Capesius BMC Cancer 2004, 4:37 (19 July 2004)

Abstract | Full text | PDF | PubMed

5.

6204
Accesses

Research article   Open Access Highly Accessed

Nottingham Prognostic Index in Triple-Negative Breast Cancer: a reliable prognostic tool?

André Albergaria, Sara Ricardo, Fernanda Milanezi, Vítor Carneiro, Isabel Amendoeira, Daniella Vieira, Jorge Cameselle-Teijeiro, Fernando Schmitt BMC Cancer 2011, 11:299 (15 July 2011)

Abstract | Full text | PDF | PubMed

6.

6150
Accesses

Research article   Open Access Highly Accessed

Classical homeopathy in the treatment of cancer patients - a prospective observational study of two independent cohorts

Matthias Rostock, Johannes Naumann, Corina Guethlin, Lars Guenther, Hans H Bartsch, Harald Walach BMC Cancer 2011, 11:19 (17 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 4 comments

7.

5715
Accesses

Research article   Open Access Highly Accessed

A retrospective study of neoadjuvant FOLFIRINOX in unresectable or borderline-resectable locally advanced pancreatic adenocarcinoma

Peter J Hosein, Jessica Macintyre, Carolina Kawamura, Jennifer Maldonado, Vinicius Ernani, Arturo Loaiza-Bonilla, Govindarajan Narayanan, Afonso Ribeiro, Lorraine Portelance, Jaime R Merchan, Joe U Levi, Caio M Rocha-Lima BMC Cancer 2012, 12:199 (29 May 2012)

Abstract | Full text | PDF | PubMed

8.

5604
Accesses

Research article   Open Access Highly Accessed

Coffee consumption and risk of cancers: a meta-analysis of cohort studies

Xiaofeng Yu, Zhijun Bao, Jian Zou, Jie Dong BMC Cancer 2011, 11:96 (15 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

9.

5417
Accesses

Research article   Open Access Highly Accessed

Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition

Tobias M Gorges, Ingeborg Tinhofer, Michael Drosch, Lars Röse, Thomas M Zollner, Thomas Krahn, Oliver von Ahsen BMC Cancer 2012, 12:178 (16 May 2012)

Abstract | Full text | PDF | PubMed

10.

5305
Accesses

Research article   Open Access Highly Accessed

Gastric cancer surgery: Billroth I or Billroth II for distal gastrectomy?

Birendra K Sah, Ming-Min Chen, Min Yan, Zheng-Gang Zhu BMC Cancer 2009, 9:428 (9 December 2009)

Abstract | Full text | PDF | PubMed

11.

5024
Accesses

Case report   Open Access Highly Accessed

Primary pancreatic lymphoma – pancreatic tumours that are potentially curable without resection, a retrospective review of four cases

Peter S Grimison, Melvin T Chin, Michelle L Harrison, David Goldstein BMC Cancer 2006, 6:117 (4 May 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

12.

4911
Accesses

Research article   Open Access Highly Accessed

Survival of cancer patients treated with mistletoe extract (Iscador): a systematic literature review

Thomas Ostermann, Christa Raak, Arndt Büssing BMC Cancer 2009, 9:451 (18 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

13.

4877
Accesses

Case report   Open Access Highly Accessed

Li-Fraumeni syndrome with simultaneous osteosarcoma and liver cancer: Increased expression of a CD44 variant isoform after chemotherapy

Go J Yoshida, Yasushi Fuchimoto, Tomoo Osumi, Hiroyuki Shimada, Seiichi Hosaka, Hideo Morioka, Makio Mukai, Yohei Masugi, Michiie Sakamoto, Tatsuo Kuroda BMC Cancer 2012, 12:444 (2 October 2012)

Abstract | Full text | PDF | PubMed

14.

4689
Accesses

Research article   Open Access Highly Accessed

The knowledge and attitudes of breast self-examination and mammography in a group of women in a rural area in western Turkey

Pınar Dündar, Dilek Özmen, Beyhan Öztürk, Gökçe Haspolat, Filiz Akyıldız, Sümeyra Çoban, Gamze Çakıroğlu BMC Cancer 2006, 6:43 (24 February 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

15.

4626
Accesses

Research article   Open Access Highly Accessed

A molecular computational model improves the preoperative diagnosis of thyroid nodules

Sara Tomei, Ivo Marchetti, Katia Zavaglia, Francesca Lessi, Alessandro Apollo, Paolo Aretini, Giancarlo Di Coscio, Generoso Bevilacqua, Chiara Mazzanti BMC Cancer 2012, 12:396 (7 September 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A molecular computational model based on the expression of 8 genes can preoperatively distinguish benign from malignant thyroid lesions and could help identify patients with thyroid nodules who do not require radical surgery.

16.

4549
Accesses

Research article   Open Access Highly Accessed

Identification of a biomarker panel for colorectal cancer diagnosis

Amaia García-Bilbao, Rubén Armañanzas, Ziortza Ispizua, Begoña Calvo, Ana Alonso-Varona, Iñaki Inza, Pedro Larrañaga, Guillermo López-Vivanco, Blanca Suárez-Merino, Mónica Betanzos BMC Cancer 2012, 12:43 (26 January 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

17.

4481
Accesses

Research article   Open Access Highly Accessed

Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1

Ho-Keun Kwon, Ji-Sun Hwang, Jae-Seon So, Choong-Gu Lee, Anupama Sahoo, Jae-Ha Ryu, Won Jeon, Byoung Ko, Chang-Rok Im, Sung Lee, Zee Park, Sin-Hyeog Im BMC Cancer 2010, 10:392 (24 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

4441
Accesses

Research article   Open Access Highly Accessed

Imagable 4T1 model for the study of late stage breast cancer

Kai Tao, Min Fang, Joseph Alroy, G Gary Sahagian BMC Cancer 2008, 8:228 (9 August 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

19.

4406
Accesses

Research article   Open Access Highly Accessed

The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time

Junliang Ma, Lunxu Liu, Guowei Che, Nanbin Yu, Fuqiang Dai, Zongbing You BMC Cancer 2010, 10:112 (25 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

4391
Accesses

Study protocol   Open Access Highly Accessed

Manual lymphatic drainage therapy in patients with breast cancer related lymphoedema

Marta Martín, Miguel A Hernández, Cristina Avendaño, Francisco Rodríguez, Helena Martínez BMC Cancer 2011, 11:94 (9 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

21.

4347
Accesses

Debate   Open Access Highly Accessed

Pancreatic cancer and depression: myth and truth

Martina Mayr, Roland M Schmid BMC Cancer 2010, 10:569 (20 October 2010)

Abstract | Full text | PDF | PubMed

22.

4290
Accesses

Research article   Open Access Highly Accessed

A mouse model for triple-negative breast cancer tumor-initiating cells (TNBC-TICs) exhibits similar aggressive phenotype to the human disease

Punit Kaur, Ganachari M Nagaraja, Hongying Zheng, Dawit Gizachew, Moses Galukande, Sunil Krishnan, Alexzander Asea BMC Cancer 2012, 12:120 (27 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

23.

4198
Accesses

Research article   Open Access Highly Accessed

Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states

Aaron L Sarver, Amy J French, Pedro M Borralho, Venugopal Thayanithy, Ann L Oberg, Kevin AT Silverstein, Bruce W Morlan, Shaun M Riska, Lisa A Boardman, Julie M Cunningham, Subbaya Subramanian, Liang Wang, Tom C Smyrk, Cecilia MP Rodrigues, Stephen N Thibodeau, Clifford J Steer BMC Cancer 2009, 9:401 (18 November 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

4167
Accesses

Research article   Open Access Highly Accessed

The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients

Catharina Medrek, Fredrik Pontén, Karin Jirström, Karin Leandersson BMC Cancer 2012, 12:306 (23 July 2012)

Abstract | Full text | PDF | PubMed

25.

4126
Accesses

Research article   Open Access Highly Accessed

Magnetic resonance imaging for lung cancer detection: Experience in a population of more than 10,000 healthy individuals

Nai-Yuan Wu, Hui-Cheng Cheng, James S Ko, Yu-Chen Cheng, Po-Wei Lin, Wei-Chan Lin, Cheng-Yen Chang, Der-Ming Liou BMC Cancer 2011, 11:242 (13 June 2011)

Abstract | Full text | PDF | PubMed

26.

4067
Accesses

Research article   Open Access Highly Accessed

Steroid hormone receptor expression in ovarian cancer: progesterone receptor B as prognostic marker for patient survival

Miriam Lenhard, Lennerová Tereza, Sabine Heublein, Nina Ditsch, Isabelle Himsl, Doris Mayr, Klaus Friese, Udo Jeschke BMC Cancer 2012, 12:553 (24 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Estrogen receptors ER-alpha/-beta and progesterone receptors PR-A/-B are frequently expressed in ovarian cancer with a certain variability relating to histological subtype, grade and stage; and multivariate analysis suggests that PR-B is an independent prognostic marker for patient survival.

27.

4060
Accesses

Research article   Open Access Highly Accessed

Specific genes involved in synthesis and editing of heparan sulfate proteoglycans show altered expression patterns in breast cancer

Iván Fernández-Vega, Olivia García, Ainara Crespo, Sonia Castañón, Primitiva Menéndez, Aurora Astudillo, Luis M Quirós BMC Cancer 2013, 13:24 (17 January 2013)

Abstract | Full text | PDF | PubMed

28.

3992
Accesses

Research article   Open Access Highly Accessed

Quality of life in patients with breast cancer before and after diagnosis: an eighteen months follow-up study

Ali Montazeri, Mariam Vahdaninia, Iraj Harirchi, Mandana Ebrahimi, Fatemeh Khaleghi, Soghra Jarvandi BMC Cancer 2008, 8:330 (11 November 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

29.

3948
Accesses

Research article   Open Access Highly Accessed

Diagnostic value of fine-needle aspiration biopsy for breast mass: a systematic review and meta-analysis

Ying-Hua Yu, Wei Wei, Jian-Lun Liu BMC Cancer 2012, 12:41 (25 January 2012)

Abstract | Full text | PDF | PubMed

30.

3926
Accesses

Research article   Open Access Highly Accessed

Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature

Andrea Köhrmann, Ulrike Kammerer, Michaela Kapp, Johannes Dietl, Jelena Anacker BMC Cancer 2009, 9:188 (16 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

31.

3894
Accesses

Review   Open Access Highly Accessed

Myeloid malignancies: mutations, models and management

Anne Murati, Mandy Brecqueville, Raynier Devillier, Marie-Joelle Mozziconacci, Véronique Gelsi-Boyer, Daniel Birnbaum BMC Cancer 2012, 12:304 (23 July 2012)

Abstract | Full text | PDF | PubMed

32.

3888
Accesses

Research article   Open Access Highly Accessed

Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

Junlin Li, Binhua P Zhou BMC Cancer 2011, 11:49 (1 February 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Activation of beta-catenin and Akt pathways by Twist is required for the maintenance of epithelial-mesenchymal transition-associated cancer stem cell-like properties such as morphological change, tumorsphere formation and expression of ALDH1 and CD44.

33.

3766
Accesses

Review   Open Access Highly Accessed

Breast cancer stem cells: tools and models to rely on

Emmanuelle Charafe-Jauffret, Christophe Ginestier, Daniel Birnbaum BMC Cancer 2009, 9:202 (25 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

34.

3754
Accesses

Research article   Open Access Highly Accessed

Salinomycin induces cell death and differentiation in head and neck squamous cell carcinoma stem cells despite activation of epithelial-mesenchymal transition and Akt

Selena Z Kuo, Katherine J Blair, Elham Rahimy, Alan Kiang, Eric Abhold, Jian-Bing Fan, Jessica Wang-Rodriguez, Xabier Altuna, Weg M Ongkeko BMC Cancer 2012, 12:556 (24 November 2012)

Abstract | Full text | PDF | PubMed

35.

3740
Accesses

Research article   Open Access Highly Accessed

Hypoxic enhancement of exosome release by breast cancer cells

Hamish W King, Michael Z Michael, Jonathan M Gleadle BMC Cancer 2012, 12:421 (24 September 2012)

Abstract | Full text | PDF | PubMed

36.

3690
Accesses

Research article   Open Access Highly Accessed

The role of major duct excision and microdochectomy in the detection of breast carcinoma

Mary F Dillon, Shah R Mohd Nazri, Shaaira Nasir, Enda W McDermott, Denis Evoy, Thomas B Crotty, Niall O'Higgins, Arnold DK Hill BMC Cancer 2006, 6:164 (23 June 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

37.

3684
Accesses

Research article   Open Access Highly Accessed

MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma

Li Cui, Hua Zhou, Hu Zhao, Yaojun Zhou, Renfang Xu, Xianlin Xu, Lu Zheng, Zhong Xue, Wei Xia, Bo Zhang, Tao Ding, Yunjie Cao, Zinong Tian, Qianqian Shi, Xiaozhou He BMC Cancer 2012, 12:546 (23 November 2012)

Abstract | Full text | PDF | PubMed

38.

3672
Accesses

Research article   Open Access Highly Accessed

"A novel in vivo model for the study of human breast cancer metastasis using primary breast tumor-initiating cells from patient biopsies"

Carolyn G Marsden, Mary Wright, Latonya Carrier, Krzysztof Moroz, Radhika Pochampally, Brian G Rowan BMC Cancer 2012, 12:10 (10 January 2012)

Abstract | Full text | PDF | PubMed

39.

3614
Accesses

Research article   Open Access Highly Accessed

Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker

Bhumsuk Keam, Seock-Ah Im, Sae-Won Han, Hye Ham, Min A Kim, Do-Youn Oh, Se-Hoon Lee, Jee Kim, Dong-Wan Kim, Tae-You Kim, Dae Heo, Woo Kim, Yung-Jue Bang BMC Cancer 2008, 8:148 (27 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

40.

3579
Accesses

Research article   Open Access Highly Accessed

MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer

Kah Chang, Pieter Mestdagh, Jo Vandesompele, Michael J Kerin, Nicola Miller BMC Cancer 2010, 10:173 (29 April 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

41.

3542
Accesses

Research article   Open Access Highly Accessed

Early detection of breast cancer: benefits and risks of supplemental breast ultrasound in asymptomatic women with mammographically dense breast tissue. A systematic review

Monika Nothacker, Volker Duda, Markus Hahn, Mathias Warm, Friedrich Degenhardt, Helmut Madjar, Susanne Weinbrenner, Ute-Susann Albert BMC Cancer 2009, 9:335 (20 September 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

42.

3490
Accesses

Research article   Open Access Highly Accessed

Impact of maximum Standardized Uptake Value (SUVmax) evaluated by 18-Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (18F-FDG-PET/CT) on survival for patients with advanced renal cell carcinoma: a preliminary report

Kazuhiro Namura, Ryogo Minamimoto, Masahiro Yao, Kazuhide Makiyama, Takayuki Murakami, Futoshi Sano, Narihiko Hayashi, Ukihide Tateishi, Hanako Ishigaki, Takeshi Kishida, Takeshi Miura, Kazuki Kobayashi, Sumio Noguchi, Tomio Inoue, Yoshinobu Kubota, Noboru Nakaigawa BMC Cancer 2010, 10:667 (3 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

43.

3484
Accesses

Research article   Open Access Highly Accessed

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer

Alexandria M Haslehurst, Madhuri Koti, Moyez Dharsee, Paulo Nuin, Ken Evans, Joseph Geraci, Timothy Childs, Jian Chen, Jieran Li, Johanne Weberpals, Scott Davey, Jeremy Squire, Paul C Park, Harriet Feilotter BMC Cancer 2012, 12:91 (19 March 2012)

Abstract | Full text | PDF | PubMed

44.

3427
Accesses

Review   Open Access Highly Accessed

Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention

Vasilis P Androutsopoulos, Aristidis M Tsatsakis, Demetrios A Spandidos BMC Cancer 2009, 9:187 (16 June 2009)

Abstract | Full text | PDF | PubMed

45.

3425
Accesses

Research article   Open Access Highly Accessed

Cardiotoxicity of anthracycline agents for the treatment of cancer: Systematic review and meta-analysis of randomised controlled trials

Lesley A Smith, Victoria R Cornelius, Christopher J Plummer, Gill Levitt, Mark Verrill, Peter Canney, Alison Jones BMC Cancer 2010, 10:337 (29 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

46.

3411
Accesses

Research article   Open Access Highly Accessed

Gefitinib (IRESSA) sensitive lung cancer cell lines show phosphorylation of Akt without ligand stimulation

Rintaro Noro, Akihiko Gemma, Seiji Kosaihira, Yutaka Kokubo, Mingwei Chen, Masahiro Seike, Kiyoko Kataoka, Kuniko Matsuda, Tetsuya Okano, Yuji Minegishi, Akinobu Yoshimura, Shoji Kudoh BMC Cancer 2006, 6:277 (6 December 2006)

Abstract | Full text | PDF | PubMed

47.

3349
Accesses

Research article   Open Access Highly Accessed

Interaction and uptake of exosomes by ovarian cancer cells

Cristina Escrevente, Sascha Keller, Peter Altevogt, Júlia Costa BMC Cancer 2011, 11:108 (27 March 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

48.

3304
Accesses

Debate   Open Access Highly Accessed

Natural resistance to cancers: a Darwinian hypothesis to explain Peto’s paradox

Benjamin Roche, Michael E Hochberg, Aleah F Caulin, Carlo C Maley, Robert A Gatenby, Dorothée Misse, Frédéric Thomas BMC Cancer 2012, 12:387 (3 September 2012)

Abstract | Full text | PDF | PubMed

49.

3266
Accesses

Research article   Open Access Highly Accessed

SNP-SNP interactions in breast cancer susceptibility

Venüs Onay, Laurent Briollais, Julia A Knight, Ellen Shi, Yuanyuan Wang, Sean Wells, Hong Li, Isaac Rajendram, Irene L Andrulis, Hilmi Ozcelik BMC Cancer 2006, 6:114 (3 May 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

SNP-SNP interactions among genes involved in different cancer-related pathways are associated with increased breast cancer risk, although the individual SNPs of these genes are not.

50.

3231
Accesses

Research article   Open Access Highly Accessed

Omega-3 fatty acids are protective against paclitaxel-induced peripheral neuropathy: A randomized double-blind placebo controlled trial

Zohreh Ghoreishi, Ali Esfahani, Abolghasem Djazayeri, Mahmoud Djalali, Banafsheh Golestan, Hormoz Ayromlou, Shahriar Hashemzade, Mohammad Asghari Jafarabadi, Vahid Montazeri, Seyed Keshavarz, Masoud Darabi BMC Cancer 2012, 12:355 (15 August 2012)

Abstract | Full text | PDF | PubMed

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