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Editor-in-Chief
Melissa Norton, MD

Medical Editor
Jigisha Patel, MRCP PhD

In-house Editor
Iratxe Puebla



BMC  BMC Cancer, Volume 8


Research article
Vinorelbine-based salvage therapy in HER2-positive metastatic breast cancer patients progressing during trastuzumab-containing regimens: a retrospective study
Filippo Montemurro, Stefania Redana, Franco Nole, Michela Donadio, Maria Elena Jacomuzzi, Giorgio Valabrega, Giuseppe Viale, Anna Sapino, Massimo Aglietta
BMC Cancer 2008, 8:209 (24July2008)
[Abstract] [Provisional PDF]

Research article
Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue
Li-Shu Wang, Yi-Wen Huang, Suling Liu, Pearlly Yan, Young C Lin
BMC Cancer 2008, 8:208 (24July2008)
[Abstract] [Provisional PDF]

Study protocol
ProsCan for Men: Randomised controlled trial of a decision support intervention for men with localised prostate cancer
Suzanne K Chambers, Megan Ferguson, R A Gardiner, David Nicol, Louisa Gordon, Stefano Occhipinti, Joanne Aitken
BMC Cancer 2008, 8:207 (24July2008)
[Abstract] [Provisional PDF]

Research article
ENMD-1198, a novel tubulin-binding agent reduces HIF-1 and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo
Christian Moser, Sven A Lang, Akira Mori, Claus Hellerbrand, Hans J Schlitt, Edward K Geissler, William E Fogler, Oliver Stoeltzing
BMC Cancer 2008, 8:206 (23July2008)
[Abstract] [Provisional PDF]

Research article
Underexpression of Deleted in liver cancer 2 (DLC2) is associated with overexpression of RhoA and poor prognosis in hepatocellular carcinoma
Li Xiaorong, Wu Wei, Qian Liyuan, Yang Kaiyan
BMC Cancer 2008, 8:205 (23July2008)
[Abstract] [Provisional PDF]

Research article
p53 expression is significantly correlated with high risk of malignancy and epithelioid differentiation in gastrointestinal stromal tumors. An immunohistochemical study with 104 GISTs.
Ursula Pauser, Nina Schmedt auf der Gunne, Gunter Kloppel, Hartmut Merz, Alfred C Feller
BMC Cancer 2008, 8:204 (23July2008)
[Abstract] [Provisional PDF]

Research article
A family history of breast cancer will not predict female early onset breast cancer in a population-based setting
Geertruida H De Bock, Catharina E Jacobi, Caroline Seynaeve, Elly M.M. Krol-Warmerdam, Jannet Blom, Christi J. Van Asperen, Cees J. Cornelisse, Jan G.M. Klijn, Peter Devilee, Rob A.E.M. Tollenaar, Cecile T.M Brekelmans, Johannes C. Van Houwelingen
BMC Cancer 2008, 8:203 (23July2008)
[Abstract] [Provisional PDF]

Research article
Evaluation of high-risk Human papillomaviruses type distribution in cervical cancer in Sichuan province of China
En-qi Wu, Guo-nan Zhang, Xiang-hui Yu, Yuan Ren, Ying Fan, Yong-ge Wu, Wei Kong, Xiao Zha
BMC Cancer 2008, 8:202 (22July2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Cell Killing and Resistance in Pre-Operative Breast Cancer Chemotherapy
Paolo Ubezio, David Cameron
BMC Cancer 2008, 8:201 (21July2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease.
Gary Beale, Dipanker Chattopadhyay, Joe Gray, Stephen Stewart, Mark Hudson, Christopher Day, Paolo Trerotoli, Gianluigi Giannelli, Derek Manas, Helen Reeves
BMC Cancer 2008, 8:200 (18July2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
The function of BCL9 in Wnt/-catenin signaling and colorectal cancer cells
Marc de la Roche, Jesper Worm, Mariann Bienz
BMC Cancer 2008, 8:199 (15July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Technical advance
A novel circular invasion assay mimics in vivo invasive behavior of cancer cell lines and distinguishes single-cell motility in vitro
Yoonseok Kam, Cherise Guess, Lourdes Estrada, Brandy Weidow, Vito Quaranta
BMC Cancer 2008, 8:198 (14July2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice
Dominika Nowis, Marek Bugajski, Magdalena Winiarska, Jacek Bil, Angelika Szokalska, Pawel Salwa, Tadeusz Issat, Halina Was, Alicja Jozkowicz, Jozef Dulak, Tomasz Stoklosa, Jakub Golab
BMC Cancer 2008, 8:197 (11July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Localization of hRad9 in breast cancer
Vivian Chan, US Khoo, MS Wong, Ken Lau, Dacita Suen, George Li, Ava Kwong, TK Chan
BMC Cancer 2008, 8:196 (11July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
A single dose of pegfilgrastim compared with daily filgrastim for supporting neutrophil recovery in patients treated for low-to-intermediate risk acute myeloid leukemia: results from a randomized, double-blind, phase 2 trial
Jorge Sierra, Jeffrey Szer, Jeannine Kassis, Richard Herrmann, Mario Lazzarino, Xavier Thomas, Stephen J Noga, Nigel Baker, Roger Dansey, Alberto Bosi
BMC Cancer 2008, 8:195 (10July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Tumor marker utility and prognostic relevance of cathepsin B, cathepsin L, urokinase-type plasminogen activator, plasminogen activator inhibitor type-1, CEA and CA 19-9 in colorectal cancer
Lszl Hersznyi, Fabio Farinati, Romilda Cardin, Gbor Istvn, Lszl D Molnr, Istvn Hritz, Massimo De Paoli, Mario Plebani, Zsolt Tulassay
BMC Cancer 2008, 8:194 (10July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
EVI1 activation in blast crisis CML due to juxtaposition to the rare 17q22 partner region as part of a 4-way variant translocation t(9;22)
An De Weer, Bruce Poppe, Barbara Cauwelier, Andre Carlier, Jan Dierick, Bruno Verhasselt, Jan Philipp, Nadine Van Roy, Frank Speleman
BMC Cancer 2008, 8:193 (9July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
Gemcitabine based combination chemotherapy in advanced pancreatic cancer-indirect comparison
Asma Sultana, Paula Ghaneh, David Cunningham, Naureen Starling, John P Neoptolemos, Catrin Tudur Smith
BMC Cancer 2008, 8:192 (8July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article
TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21Cip1 or Rb status
Sharon Sheahan, Christopher O Bellamy, Stephen N Harland, David J Harrison, Sandrine Prost
BMC Cancer 2008, 8:191 (8July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review
Kaposi sarcoma in unusual locations
Liron Pantanowitz, Bruce J Dezube
BMC Cancer 2008, 8:190 (7July2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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