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Editor-in-Chief Melissa Norton, MD
Medical Editor Jigisha Patel, MRCP PhD
In-house Editor Rachel Neilan MSc
Welcome to BMC Cancer published by BioMed Central
BMC Cancer is an open access journal publishing original peer-reviewed research articles in all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions concerning molecular and cellular biology, genetics, epidemiology, and clinical trials.
BMC Cancer (ISSN 1471-2407) is indexed/tracked/covered by PubMed, MEDLINE, CAS, EMBASE, Scopus, Current Contents, Thomson Reuters (ISI) and Google Scholar.
BMC Cancer 2009, 9 :421
Plasma levels of vascular endothelial growth factor differentiate responders to first-line platinum-based chemotherapy from non-responders and predict early disease progression in patients with non-small cell lung cancer.
BMC Cancer 2009, 9 :414
An extract of broccoli sprouts enriched with selenium inhibits proliferation, induces apoptosis and decreases prostate-specific antigen secretion in human prostate cancer cell lines, showing potential of this nutriceutical for prostate cancer management.
BMC Cancer 2009, 9 :411
The tyrosine kinase receptor for hepatocyte growth factor (HGF), c-Met, is highly expressed on neuroblastoma cells, and a small-molecule inhibitor of c-Met inhibits HGF-induced migration and proliferation of these tumor cells in a dose-dependent manner.
BMC Cancer 2009, 9 :404
While low-level laser therapy can reduce proliferation of melanoma cells in vitro, administration at high doses increases tumor growth in vivo, which suggests that this type of irradiation should be avoided over melanomas.
BMC Cancer 2009, 9 :364
Stage at diagnosis, first-course treatment and ethnicity explain lower breast cancer survival among women of low socioeconomic status, which calls for higher screening and treatment coverage in this group in order to reduce disparities.
Related content published in BMC Proceedings
New York, USA. 10 November 2007 BMC Proceedings 2008,
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Latest articles published in BMC Cancer [more info ]
Research article
Molecular risk assessment of BIG 1-98 participants by expression profiling using RNA from archival tissue Janine Antonov, Vlad Popovici, Mauro Delorenzi, Pratyaksha Wirapati, Anna Baltzer, Andrea Oberli, Beat Thurlimann, Anita Giobbie-Hurder, Giuseppe Viale, Hans Jorg Altermatt, Stefan Aebi, Rolf Jaggi BMC Cancer 2010, 10 :37 (9 February 2010) [Abstract ] [Provisional PDF ]
Research article
A polymorphism at the 3'-UTR region of the aromatase gene defines a subgroup of postmenopausal breast cancer patients with poor response to neoadjuvant letrozole Zaida Garcia-Casado, Angel Guerrero-Zotano, Antonio Llombart-Cussac, Ana Calatrava, Antonio Fernandez-Serra, Amparo Ruiz-Simon, Joaquin Gavila, Miguel A Climent, Sergio Almenar, Jose Cervera-Deval, Josefina Campos, Carlos Vazquez-Albaladejo, Antonio Llombart-Bosch, Vicente Guillem, Jose A Lopez-Guerrero BMC Cancer 2010, 10 :36 (9 February 2010) [Abstract ] [Provisional PDF ]
Research article
Mammographic density and markers of socioeconomic status: a cross-sectional study Zoe Aitken, Kate Walker, Bernardine H Stegeman, Petra A Wark, Sue M Moss, Valerie A McCormack, Isabel dos Santos Silva BMC Cancer 2010, 10 :35 (9 February 2010) [Abstract ] [Provisional PDF ]
Research article
Onconase responsive genes in human mesothelioma cells: implications for an RNA damaging therapeutic agent Deborah A Altomare, Susanna M Rybak, Jianming Pei, Jacob V Maizel, Mitchell Cheung, Joseph R Testa, Kuslima Shogen BMC Cancer 2010, 10 :34 (5 February 2010) [Abstract ] [Provisional PDF ]
Research article
Small RNA interference-mediated gene silencing of heparanase abolishes the invasion, metastasis and angiogenesis of gastric cancer cells Liduan Zheng, Guosong Jiang, Hong Mei, Jiarui Pu, Jihua Dong, Xiaohua Hou, Qiangsong Tong BMC Cancer 2010, 10 :33 (5 February 2010) [Abstract ] [Provisional PDF ]
Research article
Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation Yanyuan Wu, Monica Alvarez, Dennis J Slamon, Phillip Koeffler, Jaydutt V Vadgama BMC Cancer 2010, 10 :32 (4 February 2010) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Endometrial cancer in Puerto Rico: incidence, mortality and survival (1992-2003) Ana P Ortiz, Javier Perez, Yomayra Otero-Dominguez, Omar Garcia-Rodriguez, Sheyla Garced-Tirado, Frances Escalera-Maldonado, Sadja Gaud-Quintana, Elvis Santiago-Rodriguez, Katherine Svensson, Jose L Vergara-Arroyo, Karen Ortiz, Mariela Torres, Guillermo Tortolero-Luna, Nayda Figueroa-Valles BMC Cancer 2010, 10 :31 (3 February 2010) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
BCNU for recurrent glioblastoma multiforme: efficacy, toxicity and prognostic factors Thomas Reithmeier, Erika Graf, Tobias Piroth, Michael Trippel, Marcus O Pinsker, Guido Nikkhah BMC Cancer 2010, 10 :30 (2 February 2010) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model Jacob E Koskimaki, Emmanouil D Karagiannis, Benjamin C Tang, Hans Hammers, D NEIL Watkins, Roberto Pili, Aleksander S Popel BMC Cancer 2010, 10 :29 (1 February 2010) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Trastuzumab with either docetaxel or vinorelbine as first-line treatment for patients with HER2-positive advanced breast cancer: a retrospective comparison Stefania Redana, Michela Donadio, Franco Nole, Maria Elena Jacomuzzi, Alessandra Beano, Rossella Martinello, Anna Sapino, Giuseppe Viale, Massimo Aglietta, Filippo Montemurro BMC Cancer 2010, 10 :28 (1 February 2010) [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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Research
Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation Junya Kobayashi, Akihiro Kato, Yosuke Ota, Reiko Ohba, Kenshi Komatsu Molecular Cancer 2010, 9 :34 (9 February 2010) [Abstract ] [Provisional PDF ]
Research article
Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma. Jill C Rubinstein, Nam Tran, Shuangge Ma, Ruth Halaban, Michael Krauthammer BMC Medical Genomics 2010, 3 :4 (9 February 2010) [Abstract ] [Provisional PDF ]
Research
Distinct expression patterns of the E3 ligase SIAH-1 and its partner Kid/KIF22 in normal tissues and in the breast tumoral processes
Heriberto Bruzzoni-Giovanelli, Plinio Fernandez, Lucia Veiga, Marie-Pierre Podgorniak, Darren J. Powell, Marcos M. Candeias, Samia Mourah, Fabien Calvo, Monica Marin Journal of Experimental & Clinical Cancer Research 2010, 29 :10 (9 February 2010) [Abstract ] [Provisional PDF ]
Case Report
Intranodal palisaded myofibroblastoma (intranodal hemorrhagic spindle cell tumor with amianthoid fibers): a case report and literature review Nilufer Onak Kandemir, Figen Barut, Turan Ekinci, Cetin Karagulle, Sukru OGUZ Ozdamar Diagnostic Pathology 2010, 5 :12 (9 February 2010) [Abstract ] [Provisional PDF ]
Research
Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol Ming Zhou, Yuhua Zhao, Yan Ding, Hao Liu, Zixing Liu, Oystein Fodstad, Adam I Riker, Sushama Kamarajugadda, Jianrong Lu, Laurie B Owen, Susan P Ledoux, Ming Tan Molecular Cancer 2010, 9 :33 (9 February 2010) [Abstract ] [Provisional PDF ]
Research
EBV-positive Hodgkin lymphoma is associated with suppression of p21cip1/waf1 and a worse prognosis Ting-Yun Liu, Shang-Ju Wu, Mi-Hsin Huang, Fei-Yun Lo, Mong-Hsun Tsai, Ching-Hwa Tsai, Su-Ming Hsu, Chung-Wu Lin Molecular Cancer 2010, 9 :32 (9 February 2010) [Abstract ] [Provisional PDF ]
Research
The density of macrophages in the invasive front is inversely correlated to liver metastasis in colon cancer Qiang Zhou, Rui-Qing Peng, Xiao-Jun Wu, Qing Xia, Jing-Hui Hou, Ya Ding, Qi-Ming Zhou, Xing Zhang, Zhi-Zhong Pan, De-Sen Wan, Yi-Xin Zeng, Xiao-Shi Zhang Journal of Translational Medicine 2010, 8 :13 (8 February 2010) [Abstract ] [Provisional PDF ]
Research
FDG-PET/CT imaging for staging and target volume delineation in conformal radiotherapy of anal carcinoma Marco Krengli, Maria E Milia, Lucia Turri, Eleonora Mones, Maria C Bassi, Barbara Cannillo, Letizia Deantonio, Gianmauro Sacchetti, Marco Brambilla, Eugenio Inglese Radiation Oncology 2010, 5 :10 (6 February 2010) [Abstract ] [Provisional PDF ]
Hypothesis
Bacteria under SOS evolve anticancer phenotypes Shatha F Dallo, Tao Weitao Infectious Agents and Cancer 2010, 5 :3 (5 February 2010) [Abstract ] [Provisional PDF ]
Research article
SNAI1 expression and the mesenchymal phenotype: an immunohistochemical study performed on 46 cases of oral squamous cell carcinoma Joerg Schwock, Grace Bradley, James C Ho, Bayardo Perez-Ordonez, David W Hedley, Jonathan C Irish, William R Geddie BMC Clinical Pathology 2010, 10 :1 (5 February 2010) [Abstract ] [Provisional PDF ]