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Editor-in-Chief Melissa Norton, MD
Medical Editor Jigisha Patel, MRCP PhD
In-house Editor Rachel Neilan MSc
Welcome to BMC Cancer published by BioMed Central
BMC Cancer is an open access journal publishing original peer-reviewed research articles in all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions concerning molecular and cellular biology, genetics, epidemiology, and clinical trials.
BMC Cancer (ISSN 1471-2407) is indexed/tracked/covered by PubMed, MEDLINE, CAS, Scopus, EMBASE, Current Contents, Thomson Reuters (ISI) and Google Scholar.
Featured articles
BMC Cancer 2009, 9 :364
Stage at diagnosis, first-course treatment and ethnicity explain lower breast cancer survival among women of low socioeconomic status, which calls for higher screening and treatment coverage in this group in order to reduce disparities.
BMC Cancer 2009, 9 :349
Physical activity of moderate-to-high intensity in the previous ten years is associated with a reduced risk of developing postmenopausal breast cancer, while activity at other periods of life is not correlated to cancer risk.
BMC Cancer 2009, 9 :320
The upregulation of follistatin in fibroadenoma and of follistatin-related gene in infiltrating ductal carcinoma indicates different specificities for these activin inhibitors in breast tumor development; both seem to counteract the antiproliferative effect of activins.
BMC Cancer 2009, 9 :300
Expression levels of drug-resistance genes in lung cancer patients correlate with cell-culture based chemosensitivity to single agents or drug combinations, suggesting the possibility of developing predictive gene expression signatures to guide personalized chemotherapy.
BMC Cancer 2009, 9 :298
Increased glioma-associated oncogene homolog 1 (GLI1) expression in human breast cancer correlates with poorer survival and a more aggressive tumor phenotype, suggesting GLI1 could be a novel biomarker for breast cancer prognosis and sub-typing.
New York, USA. 10 November 2007 BMC Proceedings 2008,
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Research article
A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB Yao Dai, Meilan Liu, Wenhua Tang, Yongming Li, Jiqin Lian, Theodore S Lawrence, Liang Xu BMC Cancer 2009, 9 :392 (6 [Abstract ] [Provisional PDF ]
Research article
Assessment of angiogenesis by CD105 antigen in epithelial salivary gland neoplasms with diverse metastatic behavior Sergio V Cardoso, Kelen Christine N Souza, Paulo Rogerio Faria, Ana Lucia A Eisenberg, Fernando L Dias, Adriano M Loyola BMC Cancer 2009, 9 :391 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Circulating levels of matrix metalloproteinase-9 (MMP-9), neutrophil gelatinase-associated lipocalin (NGAL) and their compex MMP-9/NGAL in breast cancer disease Xeni Provatopoulou, Antonia Gounaris, Eleni Kalogera, Flora Zagouri, Ioannis Flessas, Evgenios Goussetis, Afroditi Nonni, Ioannis Papassotiriou, George Zografos BMC Cancer 2009, 9 :390 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Predicting prognosis in hepatocellular carcinoma after curative surgery with common clinicopathologic parameters Ke Hao, John M Luk, Nikki P Y Lee, Mao Mao, Chunsheng Zhang, Mark D Ferguson, John Lamb, Hongyue Dai, Irene O Ng, Pak C Sham, Ronnie T P Poon BMC Cancer 2009, 9 :389 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Continuous 5-fluorouracil infusion plus long acting Octreotide in advanced well differentiated neuroendocrine carcinomas. A phase II trial of the Piemonte Oncology Network. Maria P Brizzi, Alfredo Berruti, Anna Ferrero, Enrica Milanesi, Marco Volante, Federico Castiglione, Nadia Birocco, Sebastiano Bombaci, Davide Perroni, Benedetta Ferretti, Oscar Alabiso, Libero Ciuffreda, Oscar Bertetto, Mauro Papotti, Luigi Dogliotti BMC Cancer 2009, 9 :388 (3 [Abstract ] [Provisional PDF ]
Research article
Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations. Ana Preto, Joana Goncalves, Ana P Rebocho, Joana Figueiredo, Ana M Meireles, Ana S Rocha, Helena M Vasconcelos, Hugo Seca, Raquel Seruca, Paula Soares, Manuel Sobrinho-Simoes BMC Cancer 2009, 9 :387 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The mannosylated extracellular domain of Her2/neu produced in P. pastoris induces protective antitumor immunity. Alexios Dimitriadis, Chrysanthi Gontinou, Constantin N. Baxevanis, Avgi Mamalaki BMC Cancer 2009, 9 :386 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
High frequency of tumor cells with nuclear Egr-1 protein expression in human bladder cancer is associated with disease progression Frederikke Lihme Egerod, Annette Bartels, Nils Fristrup, Michael Borre, Torben F Orntoft, Martin B Oleksiewicz, Nils Brunner, Lars Dyrskjot BMC Cancer 2009, 9 :385 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Cooperation of decay-accelerating factor and membrane cofactor protein in regulating survival of human cervical cancer cells Ling-Juan Gao, Shu-Yu Guo, You-Qun Cai, Ping-Qing Gu, Ya-Juan Su, Hui Gong, Yun Liu, Chen Chen BMC Cancer 2009, 9 :384 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting Grace E Snow, Allison C Kasper, Alexander M Busch, Elisabeth Schwarz, Katherine E Ewings, Thomas Bee, Michael J Spinella, Ethan Dmitrovsky, Sarah J Freemantle BMC Cancer 2009, 9 :383 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Vascular endothelial growth factor - prognostic factor in children with neuroblastoma: a retrospective analysis Gordana Jakovljevic, Srdjana Culic, Jasminka Stepan, Aleksandra Bonevski, Sven Seiwerth Journal of Experimental & Clinical Cancer Research 2009, 28 :143 (6 [Abstract ] [Provisional PDF ]
Short communication
No effect of cancer-associated SNP rs6983267 in the 8q24 region on co-expression of MYC and TCF7L2 in normal colon tissue Ludmila Prokunina-Olsson, Jennifer L. Hall Molecular Cancer 2009, 8 :96 (6 [Abstract ] [Provisional PDF ]
Research
Serum-dependent transcriptional networks identify distinct functional roles for H-Ras and N-Ras during initial stages of the cell cycle. Esther Castellano, Carmen Guerrero, Alejandro Nunez, Javier De Las Rivas, Eugenio Santos Genome Biology 2009, 10 :R123 (6 [Abstract ] [Provisional PDF ]
Research article
Hes-6, an inhibitor of Hes-1, is regulated by 17beta-estradiol and promotes breast cancer cell proliferation Johan Hartman, Eric WF Lam, Jan-Ake Gustafsson, Anders Strom Breast Cancer Research 2009, 11 :R79 (5 [Abstract ] [Provisional PDF ]
Research article
Cbl-Associated Protein is tyrosine phosphorylated by c-Abl and c-Src kinases Inga Fernow, Ana Tomasovic, Ann Siehoff-Icking, Ritva Tikkanen BMC Cell Biology 2009, 10 :80 (5 [Abstract ] [Provisional PDF ]
Research article
A selective eradication of human non-hereditary breast cancer cells by phenanthridine derived polyADP-ribose polymerase inhibitors
Dana Inbar-Rozensal, Asher Castiel, Leonid Visochek, David Castel, Francoise Dantzer, Shai Izraeli, Malka Cohen-Armon Breast Cancer Research 2009, 11 :R78 (5 [Abstract ] [Provisional PDF ]
Research
Aurora-A down-regulates IkappaB alpha via Akt activation and interacts with insulin-like growth factor-1 induced phosphatidylinositol 3-kinase pathway for cancer cell survival Jin-e Yao, Min Yan, Zhong Guan, Chao-bin Pan, Liang-ping Xia, Chuan-xing Li, Li-hui Wang, Zi-jie Long, Yan Zhao, Ming-wei Li, Fei-meng Zheng, Jie Xu, Dong-jun Lin, Quentin Liu Molecular Cancer 2009, 8 :95 (5 [Abstract ] [Provisional PDF ]
Research article
STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect Sean P Pitroda, Bassam T Wakim, Ravi F Sood, Mara G Beveridge, Michael A Beckett, Dhara M MacDermed, Ralph R Weichselbaum, Nikolai N Khodarev BMC Medicine 2009, 7 :68 (5 [Abstract ] [Provisional PDF ]
Research article
The Prostate Care Questionnaire for Patients (PCQ-P): Reliability, validity and acceptability. Carolyn Tarrant, Richard Baker, Andrew M Colman, Paul Sinfield, Shona Agarwal, John K Mellon, William Steward, Roger Kockelbergh BMC Health Services Research 2009, 9 :199 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology
Evaluation of 7q31 region improves the accuracy of EGFR FISH assay in non small cell lung cancer Laura Casorzo, Mara Corigliano, Paolo Ferrero, Tiziana Venesio, Mauro Risio Diagnostic Pathology 2009, 4 :36 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Featured articles 
