Section Editors

  • Ian Cree, University Hospitals Coventry and Warwickshire
  • John A Hartley, University College London
  • Manami Inoue, University of Tokyo
  • Ferdinando Mannello, University Carlo Bo of Urbino
  • Christophe Nicot, Kansas University Medical Center
  • Stephen P Povoski, The Ohio State University
  • Charles Rosser, University of Hawaii Cancer Center
  • Dirk Vordermark, Martin Luther University Halle-Wittenberg

Executive Editor

  • Dafne Solera, BioMed Central


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  • Image attributed to: Fig 6B Choudhary et al, BMC Cancer 15:427 - CC

    How tumors promote angiogenesis

    Tumor-induced downregulation of Connexin 43, a component of Gap Junctions and regulator of vessel quiescence, frees endothelium to respond to angiogenic cues and may be an imprortant mechanism of tumor vascularization.

    BMC Cancer 2015, 15:427
  • Image attributed to: By Maggie Bartlett, NHGRI - CC

    Urine testing for breast cancer

    The levels of four urinary miRNAs that are specifically altered in breast cancer patients compared to healthy controls may serve as potential non-invasive innovative biomarkers to detect primary breast cancer.

    BMC Cancer 2015, 15:193
  • Image attributed to: Fig 4A Lehmann et al BMC Cancer 15:179 - CC

    TP53 mutant signatures in breast cancer

    A novel high-throughput screening method for public cancer signature validation identifies two robust signatures that differentiate TP53 mutation status and have prognostic and predictive value for breast cancer patients.

    BMC Cancer 2015, 15:179
  • Image attributed to: From Fig 1C Platt et al, BMC Cancer 15: 171 - CC

    The point on genomics-driven oncology

    Nicola Normanno and Ian Cree comment on the role of genomics in oncology, and the issues to overcome before targeted treatment based on genomic profile can become routinely accessible to lung cancer patients.

    BMC Cancer 2015, 15:141
  • Image attributed to: From Fig 4, Vikes? et al, BMC Cancer 15:151

    Molecular features of CUPs

    Cancers of unknown primary origin (CUP) exhibit distinct molecular features compared to metastases of known origin and display signatures of chromosome instability which may account for their uncommon clinical presentation and poor outcome.

    BMC Cancer 2015, 15:151
  • Image attributed to: Fig 1, Mizuno et al, BMC Cancer 15:114

    SUVmax predicts RCC characteristics

    A higher maximum of standardized uptake value (SUVmax) on 18F-FDG PET is associated with elevated tumor levels of pAkt and pS6 protein and with aggressive behavior and metastatic potential of renal cell carcinoma (RCC).

    BMC Cancer 2015, 15:114



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Cancer and Obesity


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Functional significance of erythropoietin in renal cell carcinoma

Christudas Morais, David W Johnson, David A Vesey, and Glenda C Gobe1

BMC Cancer 2013, 13:14 (10 January 2013)

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ISSN: 1471-2407