- Joaquim M Cabral, Instituto Superior Tecnico
- Lluis Montoliu, Centro Nacional de Biotecnologia
- Mats Nilsson, Uppsala University
- Peter J Punt, TNO Microbiology & Systems Biology/Leiden University
- Marko Radic, University of Tennessee
- John J Rossi, Beckman Research Institute City of Hope
- Igor Stagljar, University of Toronto
- Neal C Stewart, University of Tennessee
- Dafne Solera, BioMed Central
Supercharging of human enteropeptidase light chain via site-directed mutagenesis greatly increases its solubility and the yield of enzyme-antibody coupling, which in turns improves assay sensitivity when used in enzyme-linked immunosorbent assays (ELISA).
Screening from a yeast-displayed library yielded one antibody fragment with high affinity and specificity towards a molecule on the surface of androgen-dependent prostate cancer cells that may be used in diagnostics and targeted drug delivery.
A novel assay based on single mouse blastocysts can detect, before implantation, whether the desired indel mutations were obtained following microinjection of the genome-editing CRISPR/Cas9 system in fertilized murine eggs.
Human recombinant antibodies that recognize Mycobacterium tuberculosis biomarker 85 B were selected by phage display and produced in mammalian cells, and can be used for the development of specific tuberculosis diagnostic kits.
News from the web
- 10 December 2014
- New way to turn genes on
- 01 December 2014
- bioliq: Complete process chain is running
- 24 November 2014
- ASU, IBM move ultrafast, low-cost DNA sequencing technology a step closer to reality
BMC Biotechnology is an open access, peer-reviewed journal that considers articles on the manipulation of biological macromolecules or organisms for use in experimental procedures, cellular and tissue engineering or in the pharmaceutical, agricultural biotechnology and allied industries.
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Section Editor's Profile
Neal Stewart is a Professor of Plant Sciences and holds the Ivan Racheff Chair of Excellence in plant molecular genetics at the University of Tennessee. He is the co-director of the Tennessee Plant Research Center and holds the position of Senior Bioscientist at Oak Ridge National Laboratory. He has served on the editorial board as an Associate Editor for BMC Biotechnology since 2005. In 2011 he started serving the journal as Section Editor for plant biotechnology. His research focuses on plant biotechnology for bioenergy, agricultural and environmental applications. His lab uses such tools from genomics to systems biology in plants. His latest book, "Research Ethics for Life Scientists" reflects a passion for teaching research integrity. Stewart is also a singer-songwriter who is trying to spend more time in Nashville.
"I love open access publishing and BMC Biotechnology. Open access gives the gift of research knowledge to the world. Open access journals such as BMC Biotechnology, have long been among my top choices to publish research from my lab"