- Joaquim M Cabral, Instituto Superior Tecnico
- Lluis Montoliu, Centro Nacional de Biotecnologia
- Mats Nilsson, Uppsala University
- Peter J Punt, TNO Microbiology & Systems Biology/Leiden University
- Marko Radic, University of Tennessee
- John J Rossi, Beckman Research Institute City of Hope
- Igor Stagljar, University of Toronto
- Neal C Stewart, University of Tennessee
- Dafne Solera, BioMed Central
Screening from a yeast-displayed library yielded one antibody fragment with high affinity and specificity towards a molecule on the surface of androgen-dependent prostate cancer cells that may be used in diagnostics and targeted drug delivery.
A novel assay based on single mouse blastocysts can detect, before implantation, whether the desired indel mutations were obtained following microinjection of the genome-editing CRISPR/Cas9 system in fertilized murine eggs.
Human recombinant antibodies that recognize Mycobacterium tuberculosis biomarker 85 B were selected by phage display and produced in mammalian cells, and can be used for the development of specific tuberculosis diagnostic kits.
A functional screening based on flow cytometry can identify multiple shRNA sequences that reduce target gene expression to predetermined levels, so that epi-allelic series of hypomorphs can be obtained and off-target effects reduced.
Marker-free transformation with a stack of resistance cisgenes from crossable species produces potato plants that are resistant to Phytophthora infestans, the pathogen that causes late blight.
News from the web
- 24 November 2014
- ASU, IBM move ultrafast, low-cost DNA sequencing technology a step closer to reality
- 28 October 2014
- Boosting biogasoline production in microbes
BMC Biotechnology is an open access, peer-reviewed journal that considers articles on the manipulation of biological macromolecules or organisms for use in experimental procedures, cellular and tissue engineering or in the pharmaceutical, agricultural biotechnology and allied industries.
BMC Biotechnology is part of the BMC series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. We offer an efficient, fair and friendly peer review service, and are committed to publishing all sound science, provided that there is some advance in knowledge presented by the work.
BMC series - open, inclusive and trusted.
BMC series blog
- 20 November 2014
- GP chlamydia testing rates: previously unexplored associations
- 18 November 2014
- Measuring the impact of humanitarian assistance
- 06 November 2014
- Behind the image: Kyle Harrington
Section Editor's Profile
Neal Stewart is a Professor of Plant Sciences and holds the Ivan Racheff Chair of Excellence in plant molecular genetics at the University of Tennessee. He is the co-director of the Tennessee Plant Research Center and holds the position of Senior Bioscientist at Oak Ridge National Laboratory. He has served on the editorial board as an Associate Editor for BMC Biotechnology since 2005. In 2011 he started serving the journal as Section Editor for plant biotechnology. His research focuses on plant biotechnology for bioenergy, agricultural and environmental applications. His lab uses such tools from genomics to systems biology in plants. His latest book, "Research Ethics for Life Scientists" reflects a passion for teaching research integrity. Stewart is also a singer-songwriter who is trying to spend more time in Nashville.
"I love open access publishing and BMC Biotechnology. Open access gives the gift of research knowledge to the world. Open access journals such as BMC Biotechnology, have long been among my top choices to publish research from my lab"
BMC Biotechnology 2014, 14:91