Nanomaterials loaded with molecular drugs have emerged as promising platforms for the treatment of human diseases, offering targeted and controlled drug delivery, thus preventing high-dose administration and drug diffusion to surrounding tissues. Nonetheless, the small size, large surface area and high bioactivity of nanomaterials may pose potential safety risks to human health, therefore requiring a comprehensive assessment of their biological effects and risks. This Collection aims to gather research that explores the development, mechanisms and applications of nanomaterial-based drug delivery systems for the treatment of human diseases such as cancer, and metabolic and inflammatory disorders.
Continuing to advance our collective understanding in this research area is essential to harness the full potential of nanomaterial-based drug delivery systems for human disease treatment. Recent advances have demonstrated the ability of nanocarriers to enhance drug selectivity and release, improve pharmacokinetics and pharmacodynamics, achieve efficient targeted delivery, and reduce toxicity and side effects in tissues and organs, overall optimizing therapeutic outcomes. Furthermore, research has highlighted the potential of nanomaterials to overcome biological barriers and deliver drugs to specific cellular targets, paving the way for personalized and precision medicine approaches.
To explore the latest advancements in nanomaterials carrying drugs and their therapeutic applications, BMC Biotechnology invites submissions to the Collection Nanomaterials loaded with molecular drugs for the treatment of chronic diseases. This Collection supports and amplifies research related to SDG 3 (Good Health and Well-being) and SDG 9 (Industry, Innovation, and Infrastructure), welcoming submissions that investigate the design, synthesis, molecular characterization, and therapeutic efficacy of drug-loaded nanoparticles, as well as their interactions within the immune microenvironment. We invite researchers and experts in the field to submit research articles that explore, but are not limited to, the following topics:
- Design and synthesis of drug-loaded nanomaterials
- Mechanisms of controlled release of loaded drugs by physical and chemical properties of nanomaterials
- Applications and regulatory mechanisms of nanomaterials in inflammation and immune microenvironment
- Applications of nanomaterials in the treatment of cardiovascular diseases, and metabolic and inflammatory disorders
- Therapeutic efficacy of drug-loaded nanomaterials in cancer therapy
- Overcoming biological barriers for targeted drug delivery
- Nanomaterial-based antibiotic and anti-inflammatory drug delivery systems
- Pharmacokinetics and pharmacodynamics of nanodrugs
- Engineering precision nanoparticles for drug delivery
- Nanomaterials in precision medicine
- Biosafety and biocompatibility of nanomaterials in the treatment of human diseases
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