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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good
Welcome to BMC Biotechnology published by BioMed Central
BMC Biotechnology is an open access journal publishing original peer-reviewed research articles in the manipulation of biological macromolecules or organisms for use in experimental procedures or in the pharmaceutical, agrobiological and allied industries.
BMC Biotechnology (ISSN 1472-6750) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Scientific (ISI) and Google Scholar.
Featured articles
BMC Biotechnology 2008, 8 :13
Stable cell lines can be generated independent of antibiotic selection by immortalizing human amniocytes, collected during amniocentesis, via the introduction of adenoviral E1 functions, offering a promising new method for use in the pharmaceutical industry.
BMC Biotechnology 2007, 7 :84
Non-fucosylated antibodies with enhanced cellular cytotoxicity can be produced by using small interfering RNA knockdown on just two of three key oligosaccharide fucose modification genes (FUT8 and GMD) in antibody-producing Chinese hamster ovary cells.
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Research article
Impact of point-mutations on the hybridization affinity of surface-bound DNA/DNA and RNA/DNA oligonucleotide-duplexes: comparison of single base mismatches and base bulges Thomas Naiser, Oliver Ehler, Jona Kayser, Timo Mai, Wolfgang Michel, Albrecht Ott BMC Biotechnology 2008, 8 :48 (13 [Abstract ] [Provisional PDF ]
Methodology article
A kinetic-based sigmoidal model for the polymerase chain reaction and its application to high-capacity absolute quantitative real-time PCR Robert G Rutledge, Donald Stewart BMC Biotechnology 2008, 8 :47 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Hydroxycamptothecin-loaded nanoparticles enhance target drug delivery and anticancer effect Anxun Wang, Su Li BMC Biotechnology 2008, 8 :46 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Flow cytometric monitoring of influenza A virus infection in MDCK cells during vaccine production Josef Schulze-Horsel, Yvonne Genzel, Udo Reichl BMC Biotechnology 2008, 8 :45 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
PCR-based gene synthesis to produce recombinant proteins for crystallization Damien Marsic, Ronny C Hughes, Miranda L Byrne-Steele, Joseph D Ng BMC Biotechnology 2008, 8 :44 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Characterization of a novel non-specific nuclease from thermophilic bacteriophage GBSV1 Qing Song, Xiaobo Zhang BMC Biotechnology 2008, 8 :43 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Differential Protein Expression Following Low Temperature Culture of Suspension CHO-K1 Cells. Niraj Kumar, Patrick Gammell, Paula Meleady, Michael Henry, Martin Clynes BMC Biotechnology 2008, 8 :42 (22 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
In vivo site-specific biotinylation of proteins within the secretory pathway using a single vector systemAndrea Predonzani, Francesca Arnoldi, Alejandro L BMC Biotechnology 2008, 8 :41 (18 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Simultaneous monitoring of independent gene expression patterns in two types of cocultured fibroblasts with different color-emitting luciferases Takako Noguchi, Masaaki Ikeda, Yoshihiro Ohmiya, Yoshihiro Nakajima BMC Biotechnology 2008, 8 :40 (17 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Electrospun micro- and nanofiber tubes for functional nervous regeneration in sciatic nerve transections Silvia Panseri, Carla Cunha, Joseph Lowery, Ubaldo Del Carro, Francesca Taraballi, Stefano Amadio, Angelo Vescovi, Fabrizio Gelain BMC Biotechnology 2008, 8 :39 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Cationic nanoparticles for delivery of amphotericin B: preparation, characterization and activity in vitro Debora B Vieira, Ana M Carmona-Ribeiro Journal of Nanobiotechnology 2008, 6 :6 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Extraction of elementary rate constants from global network analysis of E. coli central metabolism Jiao Zhao, Douglas Ridgway, Gordon Broderick, Andriy Kovalenko, Michael Ellison BMC Systems Biology 2008, 2 :41 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Genomics of an extreme psychrophile, Psychromonas ingrahamii Monica Riley, James T. Staley, Antoine Danchin, TingZhang Wang, Thomas S. Brettin, Loren J. Hauser, Miriam L. Land, Linda S. Thompson BMC Genomics 2008, 9 :210 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Implications of cellobiohydrolase glycosylation for Use in Biomass Conversion Tina Jeoh, William Michener, Micheal E Himmel, Stephen R Decker, William S Adney Biotechnology for Biofuels 2008, 1 :10 (1 [Abstract ] [Provisional PDF ]
Review
Are biofuels sustainable? The EU perspective Sam Cockerill, Chris Martin Biotechnology for Biofuels 2008, 1 :9 (1 [Abstract ] [Provisional PDF ]
Research
Metabolic regulation analysis of an ethanologenic Escherichia coli strain based on RT-PCR and enzymatic activities Montserrat Orencio-Trejo, Noemi Flores, Adelfo Escalante, Georgina Hernandez-Chavez, Francisco Bolivar, Guillermo Gosset, Alfredo Martinez Biotechnology for Biofuels 2008, 1 :8 (1 [Abstract ] [Provisional PDF ]
Review
A short review on SSF - an interesting process option for ethanol production from lignocellulosic feedstocks Kim Olofsson, Magnus Bertilsson, Gunnar Liden Biotechnology for Biofuels 2008, 1 :7 (1 [Abstract ] [Provisional PDF ]
Review
The Brazilian biofuels industry
Jose Goldemberg Biotechnology for Biofuels 2008, 1 :6 (1 [Abstract ] [Provisional PDF ]
Methodology article
A copula method for modeling directional dependence of genes
Jong-Min Kim, Yoon-Sung Jung, Engin A Sungur, Kap-Hoon Han, Changyi Park, Insuk Sohn BMC Bioinformatics 2008, 9 :225 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Genetic diversity and silencing suppression effects of Rice yellow mottle virus and the P1 protein Christelle Sire, Martine Bangratz-Reyser, Denis Fargette, Christophe Brugidou Virology Journal 2008, 5 :55 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Featured articles 
pez-Requena, Oscar R Burrone
