Articles
Volume 9 (2011) - October 2011
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Research article
Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish Robin A Kimmel, Lucas Onder, Armin Wilfinger, Elin Ellertsdottir, Dirk Meyer BMC Biology 2011, 9:75 (31 October 2011) |
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Research article
Sumo-dependent substrate targeting of the SUMO protease Ulp1 Zachary C Elmore, Megan Donaher, Brooke C Matson, Helen Murphy, Jason W Westerbeck, Oliver Kerscher BMC Biology 2011, 9:74 (28 October 2011) |
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Research article
The docking protein p130Cas regulates cell sensitivity to proteasome inhibition Ming Zhao, Kristiina Vuori BMC Biology 2011, 9:73 (28 October 2011) |
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Commentary
Proteasome inhibition, the pursuit of new cancer therapeutics, and the adaptor molecule p130Cas Dharminder Chauhan, Kenneth C Anderson BMC Biology 2011, 9:72 (28 October 2011) |
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Review
Molecular dynamics simulations and drug discovery Jacob D Durrant, J Andrew McCammon BMC Biology 2011, 9:71 (28 October 2011) Modeling the movements of atoms within macromolecules can predict their conformational flexibility to inform drug discovery. Jacob Durrant and Andrew McCammon explain how this is done in molecular dynamics simulations, reviewing both the successes and current limitations of the approach.
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Research article
Karin Lanthaler, Elizabeth Bilsland, Paul D Dobson, Harry J Moss, Pınar Pir, Douglas B Kell, Stephen G Oliver BMC Biology 2011, 9:70 (24 October 2011) |
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Commentary
Alfredo Csibi, John Blenis BMC Biology 2011, 9:69 (21 October 2011) |
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Commentary
Toward a comprehensive language for biological systems James R Faeder BMC Biology 2011, 9:68 (17 October 2011) Biology is complex, and biologists are (mostly) resistant to modeling. James Faeder, lucidly challenging this resistance, welcomes a new rule-based software package reported in a recent paper in BMC Systems Biology that begins to confront the complexity.
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Commentary
Host-parasite relationships in the genome John FY Brookfield BMC Biology 2011, 9:67 (10 October 2011) Commenting on a paper in BMC Evolutionary Biology, John Brookfield picks his way elegantly through the minefield of evolutionary issues bearing on the proliferation of transposons in the genomic ecosphere
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