This collection presents commissioned Opinion articles published in BMC Biology, to provide coverage of current or emerging topics as well as a discussion of possibly controversial views, different models and theories in the field. Our Opinion pieces are open access and free to read and share.
The replication machinery of LUCA: common origin of DNA replication and transcription
Origin of DNA replication is an enigma because the replicative DNA polymerases (DNAPs) are not homologous among the three domains of life, Bacteria, Archaea, and Eukarya. The homology between the archaeal repl...