Call for papers - Ferroptosis

Guest Editors

Haider H. Dar, PhD, University of Pittsburgh, USA
Eun-Woo Lee, PhD, Korea Research Institute of Bioscience and Biotechnology (KRIBB), South Korea
Xinxin Song, MD, PhD, UT Southwestern Medical Center, USA

Submission Status: Open | Submission Deadline: 30 November 2024

Cell death caused by lysis of the plasma membrane. BMC Biology is calling for submissions to our Collection on Ferroptosis. This Collection invites submissions on the molecular mechanisms underlying ferroptosis, its role in diseases such as cancer, neurodegenerative disorders, and ischemic injuries, and its potential use as a target in therapeutic strategies. Interdisciplinary work tackling important topics in biology from different approaches, including structural, biophysical, and computational methods, alongside more traditional cell biological research in different organisms and systems, will be welcomed for consideration.

New Content Item This Collection supports and amplifies research related to SDG 3: Ensure healthy lives and promote well-being for all at all ages.

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Meet the Guest Editors

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Haider H. Dar, PhD, Department of Environment and Occupational Health (EOH), School of Public Health (SPH), University of Pittsburgh, USA

Dr Dar's research is focused on understanding and deciphering the mechanisms of lipid peroxidation triggered programmed cell death pathways (ferroptosis and necroptosis), and their regulation in the context of diseases or injury. Decoding these mechanisms will lead to identification of new drug intervention targets and are crucial for the development of specific drugs and diagnostic procedures. One major focus is to explore ferroptosis in the context of host-pathogen interaction. For this, he is using Pseudomonas aeruginosa as a model to investigate the concept of “theft-ferroptosis” (pathogen induced ferroptosis) as a virulence mechanism particularly in immune compromised patients within hospital environment, in cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) using redox lipidomics analysis.

Eun-Woo Lee, PhD, Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), South Korea

Dr Eun-Woo Lee earned his PhD from Sungkyunkwan University, where he studied the role of MKRN1, an E3 ligase, in intrinsic and extrinsic apoptosis. During his postdoc, he also studied ubiquitination-dependent regulation of RIPK3, a key regulator of necroptosis, that is required for embryonic survival during development. In 2016, he joined Metabolic Regulation Research Center at KRIBB. His research group has investigated at the mechanism and the pathophysiological relevance of ferroptosis in various human diseases. In particular, his group focused on polyunsaturated fatty acids, phospholipids, and amino acid metabolism in ferroptosis using metabolomic and lipidomic approaches.

Xinxin Song, MD, PhD, UT Southwestern Medical Center, USA

Xinxin Song obtained her PhD degree at Peking Union Medical College in China. She completed her postdoctoral training at the University of Pittsburgh, USA. Presently, she serves as an Assistant Professor in the Department of Surgery at the Southwestern Medical Center in Dallas, USA. Her research is dedicated to exploring the mechanisms of cell death, such as apoptosis, ferroptosis, pH-dependent cell death, and immunogenic cell death, as well as their links to drug resistance.

About the Collection

BMC Biology is calling for submissions to our Collection on Ferroptosis. Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation of lipid peroxides, resulting in cell membrane damage. It has been shown to play a pivotal role in disease onset and progression, while also being implicated in cellular metabolism and immune response.

This Collection invites submissions on the molecular mechanisms underlying ferroptosis, its role in diseases such as cancer, neurodegenerative disorders, and ischemic injuries, and its potential use as a target in therapeutic strategies. Interdisciplinary work tackling important topics in biology from different approaches, including structural, biophysical, and computational methods, alongside more traditional cell biological research in different organisms and systems, will be welcomed for consideration.

Potential topics for submission include, but are not limited to:

Molecular pathways and regulatory elements in ferroptosis
The impact of ferroptosis on disease initiation and progression
Interplay between ferroptosis and other cell death modalities
Role of ferroptosis in immune response
Potential therapeutic approaches targeting ferroptosis

This Collection supports and amplifies research related to SDG 3: Ensure healthy lives and promote well-being for all at all ages.

Image credit: Kateryna_Kon / stock.adobe.com

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. To submit your manuscript to this Collection, please use our online submission system and indicate in your cover letter that you would like the article to be considered for inclusion in the "Ferroptosis" Collection.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.