BMC Biology is the flagship biology journal of the BMC series, publishing peer-reviewed research and methodology articles of special importance and broad interest in any area of biology, as well as commissioned reviews, opinion pieces, comment and Q&As on topics of special or topical interest.

Re-review opt-out In response to widespread frustration with delays to publication through iterative reviewing, we give our authors a choice (see our Editorial: Q&A: Re-review opt-out and painless publishing).


  • Miranda Robertson, BioMed Central
Beyond Mendel: modelling in biology -- An article series
Mitochondria: a cross-journal series
Open Questions


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Review & comment

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    Knowing when to stop – A theory of allometry

    Charles Stevens

    How is organ size regulated? Khammash and colleagues address this central mystery of biology with a mathematical model, and in an accompanying Commentary Charles Stevens explains why this is not ‘just a theory’.

  • Image credit: David Pincus

    Beyond equilibrium modeling in gene regulation

    David Pincus

    Jeremy Gunawardena and colleagues describe a graph-based framework for gene regulation that can accommodate non-equilibrium mechanisms. David Pincus discusses why such a theoretical framework is important.

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    The new physiology of mitochondria

    Heidi McBride

    In her open questions contribution to BMC Biology, Heidi McBride urges the importance of integrating the emerging cell and molecular biology, with all its –omics, into a new physiological understanding of the mitochondrion

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    Epigenomics of aging

    Marc Jung, Gerd Pfeifer

    There is much phenomenological evidence for a connection between DNA methylation patterns and aging. Marc Jung and Gern Pfeifer review the evidence and discuss the possible connection between methylation and the effects of dietary restriction on longevity.


Open Access
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Journal of Biology

BMC Biology assimilated the philosophy and distinguished Editorial Board and history of its sister journal Journal of Biology on fusion of the two journals in 2010. The full archive of Journal of Biology is available from its own archive website, and the objectives and aspirations of the combined journal are explained in the editorial that accompanied the fusion.

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ISSN: 1741-7007