BMC Biology is the flagship biology journal of the BMC series, publishing peer-reviewed research and methodology articles of special importance and broad interest in any area of biology, as well as commissioned reviews, opinion pieces, comment and Q&As on topics of special or topical interest.

Re-review opt-out In response to widespread frustration with delays to publication through iterative reviewing, we give our authors a choice (see our Editorial: Q&A: Re-review opt-out and painless publishing).


  • Miranda Robertson, BioMed Central
Beyond Mendel: modelling in biology -- An article series
Mitochondria: a cross-journal series
Metabolism, Diet and Disease
Open Questions


Selected articles

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Open Access
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    Mitochondrial stress detection and disease

    Mark Pellegrino, Cole Haynes

    Mark Pellegrino and Cole Haynes, in a topical review, explain how mitochondrial stress leads to failures of mitochondrial protein import that are exploited to trigger the repair or the segregation and destruction of damaged mitochondria in infection and disease

  • Image credit: BMC Biology, variant of iconic image

    Knowing when to stop – A theory of allometry

    Charles Stevens

    How is organ size regulated? Khammash and colleagues address this central mystery of biology with a mathematical model, and in an accompanying Commentary Charles Stevens explains why this is not ‘just a theory’.

  • Image credit: David Pincus

    The importance of avoiding equilibrium

    David Pincus

    No-one who knows anything about life would accuse it of being characterised by equilibrium - yet this is exactly the assumption many biological models make. Highlighting a recent paper from Jeremy Gunawardena and colleagues, David Pincus discusses why it's important to incorporate non-equilibrium states into models of gene regulation, and how theoreticians are grappling with the problems inherent in doing so.

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    The new physiology of mitochondria

    Heidi McBride

    In her open questions contribution to BMC Biology, Heidi McBride urges the importance of integrating the emerging cell and molecular biology, with all its –omics, into a new physiological understanding of the mitochondrion


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BMC Biology assimilated the philosophy and distinguished Editorial Board and history of its sister journal Journal of Biology on fusion of the two journals in 2010. The full archive of Journal of Biology is available from its own archive website, and the objectives and aspirations of the combined journal are explained in the editorial that accompanied the fusion.

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ISSN: 1741-7007