Home
Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good PhD
Welcome to BMC Biotechnology published by BioMed Central
BMC Biotechnology is an open access journal publishing original peer-reviewed research articles in the manipulation of biological macromolecules or organisms for use in experimental procedures, cellular and tissue engineering or in the pharmaceutical, agricultural biotechnology and allied industries.
BMC Biotechnology (ISSN 1472-6750) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
BMC Biotechnology 2009, 9 :82
Production of human neurons in a bioreactor by in vitro expansion of human embryonic stem cells and fast differentiation into neurons demonstrates a scalable and efficient bioprocess for producing differentiated derivatives from stem cells.
BMC Biotechnology 2009, 9 :79
Chickens are protected from developing the economically-important illness coccidiosis by eating pea seeds expressing antibodies against the parasite Eimeria, showing passive immunization to be a cost-effective method of controlling this infectious disease.
BMC Biotechnology 2009, 9 :64
Stable nuclear transformation of the green alga Gonium pectorale, using promoter sequences from related species to drive expression of a selectable marker or reporter gene, opens the way to genetic engineering in this species.
more info ]
Research article
Genetic load and transgenic mitigating genes in transgenic Brassica rapa (field mustard) x Brassica napus (oilseed rape) hybrid populations Christy W Rose, Reginald J Millwood, Hong Seok Moon, Murali R Rao, Matthew D Halfill, Paul L Raymer, Suzanne I Warwick, Hani Al-Ahmad, Jonathan Gressel, C Neal Stewart Jr BMC Biotechnology 2009, 9 :93 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Affinity maturation generates greatly improved xyloglucan-specific carbohydrate binding modules Laura von Schantz, Fredrika Gullfot, Sebastian Scheer, Lada Filonova, Lavinia Cicortas Gunnarsson, James E Flint, Geoffrey Daniel, Eva Nordberg-Karlsson, Harry Brumer, Mats Ohlin BMC Biotechnology 2009, 9 :92 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Authentication scheme for routine verification of genetically similar laboratory colonies: a trial with Anopheles gambiae Elien E Wilkins, Paula L Marcet, Alice C Sutcliffe, Paul I Howell BMC Biotechnology 2009, 9 :91 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Using a water-immiscible ionic liquid to improve asymmetric reduction of 4-(trimethylsilyl)-3-butyn-2-one catalyzed by immobilized Candida parapsilosis CCTCC M203011 cells Wen-Yong Lou, Lei Chen, Bo-Bo Zhang, Thomas J Smith, Min-Hua Zong BMC Biotechnology 2009, 9 :90 (22 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes Tanja Deurholt, Niek P van Til, Aniska A Chhatta, Lysbeth ten Bloemendaal, Ruth Schwartlander, Catherine Payne, John N Plevris, Igor M Sauer, Robert AFM Chamuleau, Ronald PJ Oude Elferink, Jurgen Seppen, Ruurdtje Hoekstra BMC Biotechnology 2009, 9 :89 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Regulated expression of a transgene introduced on an oriP/EBNA-1 PAC shuttle vector into human cells Hanne A Askautrud, Elisabet Gjernes, Gro L St BMC Biotechnology 2009, 9 :88 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Methodology article
Characterization of unknown genetic modifications using high throughput sequencing and computational subtraction Torstein Tengs, Haibo Zhang, Arne Holst-Jensen, Jon Bohlin, Melinka A Butenko, Anja Br BMC Biotechnology 2009, 9 :87 (8 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Refinement of lentiviral vector for improved RNA processing and reduced rates of self inactivation repair Rachel M Koldej, Donald S Anson BMC Biotechnology 2009, 9 :86 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Reduction of liver macrophage transduction by pseudotyping lentiviral vectors with a fusion envelope from Autographa californica GP64 and Sendai virus F2 domain David M Markusic, Niek P van Til, Johan K Hiralall, Ronald PJ Oude Elferink, Jurgen Seppen BMC Biotechnology 2009, 9 :85 (7 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Thermochemotherapy effect of nanosized As2 O3 /Fe3 O4 complex on experimental mouse tumors and its influence on the expression of CD44v6, VEGF-C and MMP-9 Yiqun Du, Dongsheng Zhang, Hui Liu, Rensheng Lai BMC Biotechnology 2009, 9 :84 (5 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research
Chimeric recombinante rotavirus-like particles as a vehicle for the display of heterologous epitopes Andrea Peralta, Paula Molinari, Oscar Taboga Virology Journal 2009, 6 :192 (6 [Abstract ] [Provisional PDF ]
Research
Laboratory-scale method for enzymatic saccharication of lignocellulosic biomass at high-solids loadings Christine M Roche, Clare J Dibble, Jonathan J Stickel Biotechnology for Biofuels 2009, 2 :28 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Transarterial chemoembolisation (TACE) using irinotecan-loaded beads for the treatment of unresectable metastases to the liver in patients with colorectal cancer: an interim report Robert CG Martin, Ken Robbins, Dana Tomalty, Ryan O'Hara, Petar Bosnjakovic, Radek Padr, Miloslav Rocek, Frantisek Slauf, Alexander Scupchenko, Cliff Tatum World Journal of Surgical Oncology 2009, 7 :80 (3 [Abstract ] [Provisional PDF ]
Review
Advancing environmental risk assessment for transgenic biofeedstock crops Jeffrey D Wolt Biotechnology for Biofuels 2009, 2 :27 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
High yield recombinant thermostable alpha-amylase production using an improved Bacillus licheniformis system Dandan Niu, Zhirui Zuo, Gui-Yang Shi, Zheng-Xiang Wang Microbial Cell Factories 2009, 8 :58 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology
An inbred line of the diploid strawberry Fragaria vesca f. semperflorens for genomic and molecular genetic studies in the Rosaceae Janet P Slovin, Kyle Schmitt, Kevin M Folta Plant Methods 2009, 5 :15 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Cassette deletion in multiple shRNA lentiviral vectors for HIV-1 and its impact on treatment success Glen J Mcintyre, Yi-Hsin Yu, Anna Tran, Angel B Jaramillo, Allison J Arndt, Michelle L Millington, Maureen P Boyd, Fiona A Elliott, Sylvie W Shen, John M Murray, Tanya L Applegate Virology Journal 2009, 6 :184 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The mannosylated extracellular domain of Her2/neu produced in P. pastoris induces protective antitumor immunity. Alexios Dimitriadis, Chrysanthi Gontinou, Constantin N. Baxevanis, Avgi Mamalaki BMC Cancer 2009, 9 :386 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Silver nanoparticles inhibit VEGF-and IL-1beta-induced vascular permeability via Src dependent pathway in porcine retinal endothelial cells Sardarpasha Sheikpranbabu, Kalimuthu Kalishwaralal, Deepak Venkataraman, Soo Hyun Eom, Jongsun Park, Sangiliyandi Gurunathan Journal of Nanobiotechnology 2009, 7 :8 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
13C-metabolic flux ratio and novel carbon path analyses confirmed that Trichoderma reesei uses primarily the respirative pathway also on the preferred carbon source glucose Paula Jouhten, Esa Pitkanen, Tiina Pakula, Markku Saloheimo, Merja Penttila, Hannu Maaheimo BMC Systems Biology 2009, 3 :104 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Featured articles
rvold, Mona M Lindeberg, Jim Thorsen, Hans Prydz, Eirik Frengen
then Kristoffersen, Hilde-Gunn Opsahl Sorteberg, Knut G Berdal