Home
Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor J. Ann Le Good PhD
Welcome to BMC Biotechnology published by BioMed Central
BMC Biotechnology is an open access journal publishing original peer-reviewed research articles in the manipulation of biological macromolecules or organisms for use in experimental procedures, cellular and tissue engineering or in the pharmaceutical, agricultural biotechnology and allied industries.
BMC Biotechnology (ISSN 1472-6750) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, FSTA, Thomson Reuters (ISI) and Google Scholar.
BMC Biotechnology 2010, 10 :3
Peripheral tissue cells have intrinsic circadian molecular oscillators, which can be detected and analyzed in primary culture cells using a Tol2-transposon-based system to transfer luciferase linked to the promoters of circadian clock genes.
BMC Biotechnology 2009, 9 :93
Brassica rapa (weed) x Brassica napus (crop) transgenic hybrids are less fit than B. rapa in competitive conditions, with crop alleles acting as a negative genetic load opposing transgene introgression, while a mitigating transgene is soon lost from hybrids.
BMC Biotechnology 2009, 9 :82
Production of human neurons in a bioreactor by in vitro expansion of human embryonic stem cells and fast differentiation into neurons demonstrates a scalable and efficient bioprocess for producing differentiated derivatives from stem cells.
more info ]
Research article
Comparative transfection of DNA into primary and transformed mammalian cells from different lineages Rosalie Maurisse, David De Semir, Hamid Emamekhoo, Babak Bedayat, Alireza Abdolmohammadi, Hooman Parsi, Dieter C Gruenert BMC Biotechnology 2010, 10 :9 (8 [Abstract ] [Provisional PDF ]
Research article
Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA Kristin S Gunnarsen, Elin Lunde, Per E Kristiansen, Bjarne Bogen, Inger Sandlie, Geir A Loset BMC Biotechnology 2010, 10 :8 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Heterologous expression of leader-less pga gene in Pichia pastoris: intracellular production of prokaryotic enzyme Helena Maresova, Zdena Markova, Renata Valesova, Jan Sklenar, Pavel Kyslik BMC Biotechnology 2010, 10 :7 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
A new approach to dual-color two-photon microscopy with fluorescent proteins Shane E Tillo, Thomas E Hughes, Nikolay S Makarov, Aleks Rebane, Mikhail Drobizhev BMC Biotechnology 2010, 10 :6 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Senescent vs. non-senescent cells in the human annulus in vivo: Cell harvest with laser capture microdissection and gene expression studies with microarray analysis
Helen E Gruber, Gretchen L Hoelscher, Jane A Ingram, Natalia Zinchenko, Edward N Hanley Jr. BMC Biotechnology 2010, 10 :5 (28 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
A novel FRET pair for detection of parallel DNA triplexes by the LightCycler Uffe V Schneider, Jette K Severinsen, Imrich Geci, Limei M Okkels, Nina Johnk, Nikolaj D Mikkelsen, Teena Klinge, Erik B Pedersen, Henrik Westh, Gorm Lisby BMC Biotechnology 2010, 10 :4 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Real-time monitoring of circadian clock oscillations in primary cultures of mammalian cells using Tol2 transposon-mediated gene transfer strategy Kazuhiro Yagita, Iori Yamanaka, Noriaki Emoto, Koichi Kawakami, Shoichi Shimada BMC Biotechnology 2010, 10 :3 (22 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Characterization of Proton Production and Consumption Associated with Microbial Metabolism Karthikeyan Srinivasan, Radhakrishnan Mahadevan BMC Biotechnology 2010, 10 :2 (20 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Functional genomics tool: Gene silencing in Ixodes scapularis eggs and nymphs by electroporated dsRNA Shahid Karim, Emily Troiano, Thomas N Mather BMC Biotechnology 2010, 10 :1 (14 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
RNA degradation compromises the reliability of microRNA expression profiling David Ibberson, Vladimir Benes, Martina U Muckenthaler, Mirco Castoldi BMC Biotechnology 2009, 9 :102 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Using simple artificial intelligence methods for predicting
amyloidogenesis in antibodies Maria Pamela C David, Gisela P Concepcion, Eduardo A Padlan BMC Bioinformatics 2010, 11 :79 (8 [Abstract ] [Provisional PDF ]
Research article
Pseudomonas aeruginosa Cystic Fibrosis isolates of similar RAPD genotype exhibit diversity in biofilm forming ability in vitro. Elena Deligianni, Sally H Pattison, Daniel Berrar, Nigel G Ternan, Richard W Haylock, John E Moore, J. Stuart Elborn, James S G Dooley BMC Microbiology 2010, 10 :38 (8 [Abstract ] [Provisional PDF ]
Research
Coupling of receptor interference and a host-dependent post-binding entry deficiency in a gammaretroviral envelope protein
Shervin Bahrami, Ditte Ejegod, Karina DALSGAARD Sorensen, Finn SKOU Pedersen Retrovirology 2010, 7 :9 (5 [Abstract ] [Provisional PDF ]
Research
Optical characterization of colloidal CdSe quantum dots in endothelial progenitor cells Matyas Molnar, Ying Fu, Peter Friberg, Yun Chen Journal of Nanobiotechnology 2010, 8 :2 (4 [Abstract ] [Provisional PDF ]
Research
Effects of liquid stimuli on dual-axis swallowing accelerometry signals in a healthy population Joon Lee, Ervin Sejdic, Catriona M Steele, Tom Chau BioMedical Engineering OnLine 2010, 9 :7 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
An evolved ribosome-inactivating protein targets and kills human melanoma cells in vitro and in vivo Melissa C Cheung, Leigh Revers, Subodini Perampalam, Xin Wei, Reza Kiarash, David E Green, Aws Abdul-Wahid, Jean Gariepy Molecular Cancer 2010, 9 :28 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
In silico feasibility of novel biodegradation pathways for 1,2,4-trichlorobenzene Stacey D Finley, Linda J Broadbelt, Vassily Hatzimanikatis BMC Systems Biology 2010, 4 :7 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
A nonsense mutation in the beta-carotene oxygenase 2 (BCO2) gene is tightly associated with accumulation of carotenoids in adipose tissue in sheep (Ovis aries) Dag I Vage, Inger A Boman BMC Genetics 2010, 11 :10 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Short report
"Color Timer" mice: visualization of neuronal differentiation with fluorescent proteins Hiroaki Kanki, Marilia KIMIE Shimabukuro, Atsushi Miyawaki, Hideyuki Okano Molecular Brain 2010, 3 :5 (2 [Abstract ] [Provisional PDF ]
Methodology article
Tracking chromosomal positions of oligomers--a case study with Illumina's BovineSNP50 beadchip Armin O. Schmitt, Ralf H. Bortfeldt, Gudrun A. Brockmann BMC Genomics 2010, 11 :80 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Featured articles
