- Paolo Bruzzi, National Cancer Research Institute
- Ian Cree, Warwick Medical School, Coventry
- Shoukat Dedhar, British Columbia Cancer Agency
- John A Hartley, University College London
- Manami Inoue, University of Tokyo
- Ferdinando Mannello, University Carlo Bo of Urbino
- Christophe Nicot, Kansas University Medical Center
- Stephen P Povoski, The Ohio State University
- Charles Rosser, University of Hawaii Cancer Center
- Dirk Vordermark, Martin Luther University Halle-Wittenberg
- Dafne Solera, BioMed Central
Administration of bevacizumab plus chemotherapy in medically fit elderly German patients with metastatic colorectal cancer (mCRC) proves effective in measures of progression-free status and overall survival in a large community-based observational cohort study.
A compound that reversibly inhibits lysine specific demethylase 1 (LSD1) causes global changes in histone methylation and displays anti-tumor effects on poorly differentiated endometrial carcinoma cell lines and in an orthotopic xenograft mouse model.
Acetylcholinesterase (AChE) delivered by adenoviral vectors inhibits cell growth and induces the mitochondrial pathway of apoptosis in gastric cancer cells, represses tumor growth in mouse xenografts, and is also effective against gastric cancer stem cells.
The three-sigma statistical threshold criteria method proves better than the 1.5-to-1 ratiometric threshold criteria method for determination of gamma detection probe positivity for in situ detection of abnormal tissue sites during radioguided oncologic surgery.
Despite the access to care programs recently implemented in Mexico, barriers to appropriate medical care still exist and affect breast cancer outcomes, contributing to the high breast cancer mortality rate in this country.
Offering HPV screening followed by cytology triage to underscreened women in developed countries could be the optimal strategy to identify women at higher risk leading to longer and safe screen intervals.
18F-fluorodeoxyglucose (18F-FDG) PET/CT can be successfully performed at extended injection-to-scan acquisition times while maintaining diagnostic image quality and has potential for real-time use of 18F-FDG PET/CT imaging in conjunction with interventional and surgical procedures.
Lipid metabolism enzyme ACSVL3 supports the malignant phenotype of glioblastoma cancer stem cells, promotes their ability to initiate and propagate tumors and may serve as a therapeutic target for brain cancer treatment.
BMC Cancer 2014, 14:785
BMC Cancer is an open access, peer-reviewed journal that considers articles on all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions concerning molecular and cellular biology, genetics, epidemiology, and clinical trials.
BMC Cancer is part of the BMC series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. We offer an efficient, fair and friendly peer review service, and are committed to publishing all sound science, provided that there is some advance in knowledge presented by the work.
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Christudas Morais, David W Johnson, David A Vesey, and Glenda C Gobe1BMC Cancer 2013, 13:14 (10 January 2013)
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