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BMC Cancer

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Editor-in-Chief
Melissa Norton, MD

Medical Editor
Jigisha Patel, MRCP PhD

In-house Editor
Rachel Neilan MSc


Welcome to BMC Cancer published by BioMed Central
BMC Cancer is an open access journal publishing original peer-reviewed research articles in all aspects of cancer research, including the pathophysiology, prevention, diagnosis and treatment of cancers. The journal welcomes submissions concerning molecular and cellular biology, genetics, epidemiology, and clinical trials. BMC Cancer (ISSN 1471-2407) is indexed/tracked/covered by PubMed, MEDLINE, CAS, EMBASE, Scopus, Current Contents, Thomson Reuters (ISI) and Google Scholar.



BMC Featured articles

Image: National Cancer Institute, 1985, Public domain
BMC Cancer 2009, 9:404
While low-level laser therapy can reduce proliferation of melanoma cells in vitro, administration at high doses increases tumor growth in vivo, which suggests that this type of irradiation should be avoided over melanomas.
Image credit: Wikipedia
BMC Cancer 2009, 9:364
Stage at diagnosis, first-course treatment and ethnicity explain lower breast cancer survival among women of low socioeconomic status, which calls for higher screening and treatment coverage in this group in order to reduce disparities.
Image credit: Jupiter Images
BMC Cancer 2009, 9:349
Physical activity of moderate-to-high intensity in the previous ten years is associated with a reduced risk of developing postmenopausal breast cancer, while activity at other periods of life is not correlated to cancer risk.
Modified from Fig 1K
BMC Cancer 2009, 9:320
The upregulation of follistatin in fibroadenoma and of follistatin-related gene in infiltrating ductal carcinoma indicates different specificities for these activin inhibitors in breast tumor development; both seem to counteract the antiproliferative effect of activins.
TheNickster, Flickr
BMC Cancer 2009, 9:300
Expression levels of drug-resistance genes in lung cancer patients correlate with cell-culture based chemosensitivity to single agents or drug combinations, suggesting the possibility of developing predictive gene expression signatures to guide personalized chemotherapy.


BMC  Related content published in BMC Proceedings


New York, USA. 10 November 2007
BMC Proceedings 2008, 2(Suppl 2)
[Content]



BMC  Latest articles published in BMC Cancer        [more info]


Research article
The Int7G24A variant of transforming growth factor-beta receptor type I is a risk factor for colorectal cancer in the male Spanish population: a case-control study
Adela Castillejo, Trinidad Mata-Balaguer, Carla Guarinos, Maria-Isabel Castillejo, Ana Martinez-Canto, Victor-Manuel Barbera, Paola Montenegro, Enrique Ochoa, Rafael Lazaro, Carmen Guillen-Ponce, Alfredo Carrato, Jose LUIS Soto
BMC Cancer 2009, 9:406 (20November2009)
[Abstract] [Provisional PDF]

Research article
Partial loss of heterozygosity events at the mutated gene in tumors from MLH1/MSH2 large genomic rearrangement carriers
Katarina Zavodna, Tomas Krivulcik, Maria Gerykova Bujalkova, Tomas Slamka, David Martinicky, Denisa Ilencikova, Zdena Bartosova
BMC Cancer 2009, 9:405 (20November2009)
[Abstract] [Provisional PDF]

Research article
The effect of low-level laser irradiation (Ga-Al-AsP - 660nm) on in vitro and in vivo melanoma
Lucio Frigo, Juliana SS Luppi, Giovani M Favero, Durvanei A Maria, Socrates C Penna, Jan M Bjordal, Rene J Bensadoun, Rodrigo Alvaro Lopes Martins
BMC Cancer 2009, 9:404 (20November2009)
[Abstract] [Provisional PDF]

Research article
Investigation into the controversial association of Streptococcus gallolyticus with colorectal cancer and adenoma
Ahmed S Abdulamir, Rand R Hafidh, Layla K Mahdi, Tarik Aljeboori, Fatimah Abu bakar
BMC Cancer 2009, 9:403 (19November2009)
[Abstract] [Provisional PDF]

Research article
Initial activation of EpCAM cleavage via cell-to-cell contact
Sabine Denzel, Dorothea Maetzel, Brigitte Mack, Carola Eggert, Gabriele Baerr, Olivier Gires
BMC Cancer 2009, 9:402 (19November2009)
[Abstract] [Provisional PDF]

Research article
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
Aaron L Sarver, Amy J French, Pedro M Borralho, Venugopal Thayanithy, Ann L Oberg, Kevin AT Silverstein, Bruce W Morlan, Shaun M Riska, Lisa A Boardman, Julie M Cunningham, Subbaya Subramanian, Liang Wang, Tom C Smyrk, Cecilia MP Rodrigues, Stephen N Thibodeau, Clifford J Steer
BMC Cancer 2009, 9:401 (18November2009)
[Abstract] [Provisional PDF]

Research article
XPD Codon 312 and 751 Polymorphisms, and AFB1 Exposure, and Hepatocellular Carcinoma Risk
Xi Dai Long, Yun Ma, Yun Feng Zhou, Jin Guang Yao, Fu Zhi Ban, Yong Zhi Huang, Bing Cheng Huang
BMC Cancer 2009, 9:400 (17November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Doxorubicin Loaded Polymeric Nanoparticulate Delivery System to Overcome Drug Resistance in Osteosarcoma
Michiro Susa, Arun K Iyer, Keinosuke Ryu, Francis J Hornicek, Henry Mankin, Mansoor M Amiji, Zhenfeng Duan
BMC Cancer 2009, 9:399 (16November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
DNA-AP sites generation by Etoposide in whole blood cells
Emilio Rojas, Patricia Mussali, Efrain Tovar, Mahara Valverde
BMC Cancer 2009, 9:398 (16November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Examination of polymorphic glutathione S-transferase (GST) genes, tobacco smoking and prostate cancer risk among Men of African Descent: A case-control study
Nicole A Lavender, Marnita L Benford, Tiva T VanCleave, Guy N Brock, Rick A Kittles, Jason H Moore, David W Hein, La Creis R Kidd
BMC Cancer 2009, 9:397 (16November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Research article
Cytotoxic and antibacterial activities of endophytic fungi isolated from plants at the National Park, Pahang, Malaysia
Nurul AMN Hazalin, Kalavathy Ramasamy, Lim SIONG Meng, Ibtisam Abdul Wahab, Anthony LJ Cole, Abu BAKAR Abdul Majeed
BMC Complementary and Alternative Medicine 2009, 9:46 (21November2009)
[Abstract] [Provisional PDF]

Review
Molecular pathogenetic mechanisms and new therapeutic perspectives in anthracycline-induced cardiomyopathy
Giuseppe Distefano
Italian Journal of Pediatrics 2009, 35:37 (20November2009)
[Abstract] [Provisional PDF]

Case report
Cardiac embolization of an implanted fiducial marker for hepatic stereotactic body radiotherapy: a case report
Hooman Hennessey, David Valenti, Tatiana Cabrera, Valerie Panet-Raymond, David Roberge
Journal of Medical Case Reports 2009, 3:140 (20November2009)
[Abstract] [Provisional PDF]

Research article
Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells
Yuko Saeki, Takaho Endo, Kaori Ide, Takeshi Nagashima, Noriko Yumoto, Tetsuro Toyoda, Harukazu Suzuki, Yoshihide Hayashizaki, Yoshiyuki Sakaki, Mariko Okada-Hatakeyama
BMC Genomics 2009, 10:545 (20November2009)
[Abstract] [Provisional PDF]

Research
iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells
Sara De Boo, Joanna Kopecka, Davide Brusa, Elena Gazzano, Lina Matera, Dario Ghigo, Amalia Bosia, Chiara Riganti
Molecular Cancer 2009, 8:108 (19November2009)
[Abstract] [Provisional PDF]

Research
Gene expression profiles of mouse spermatogenesis during recovery from irradiation
Fozia J Shah, Masami Tanaka, John E Nielsen, Teruaki Iwamoto, Shinichi Kobayashi, Niels E Skakkebaek, Henrik Leffers, Kristian Almstrup
Reproductive Biology and Endocrinology 2009, 7:130 (19November2009)
[Abstract] [Provisional PDF]

Research
Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis
Alison K. Bauer, Jennifer Fostel, Laura M. Degraff, Elizabeth A. Rondini, Christopher Walker, Sherry F. Grissom, Julie Foley, Steven R. Kleeberger
Molecular Cancer 2009, 8:107 (19November2009)
[Abstract] [Provisional PDF]

Case Report
Primary leiomyosarcoma of the male urethra: a case report
Youness Ahallal, Mohammed Fadl Tazi, Abdelhak Khallouk, Elmehdi Tazi, Amal Benlemlih, Mohammed Jamal Elfassi, Moulay Hassan Farih
Cases Journal 2009, 2:207 (18November2009)
[Abstract] [Provisional PDF]

Research article
CD 9 and vimentin distinguish clear cell from chromophobe renal cell carcinoma
Ariel A Williams, John PT Higgins, Hongjuan Zhao, Borje Ljunberg, James D Brooks
BMC Clinical Pathology 2009, 9:9 (18November2009)
[Abstract] [Provisional PDF]

Short communication
Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression
Aaron E Foster, Fatma V Okur, Ettore Biagi, An Lu, Gianpietro Dotti, Eric Yvon, Barbara Savoldo, George Carrum, Michael Andreeff, Margaret A Goodell, Helen E Heslop, Malcolm K Brenner
Molecular Cancer 2009, 8:106 (18November2009)
[Abstract] [Provisional PDF]

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