- Hans-Joachim Anders, Ludwig-Maximilians-University
- Adrian Covic, Parhon University Hospital
- Bernard Jaar, Johns Hopkins Medical Institutions
- William Oetting, University of Minnesota
- Giorgina Piccoli, University of Torino
- Donald Silverberg, Tel Aviv Medical Center
- Robert Unwin, University College London
- Hayley Henderson, BioMed Central
Mouse model studies confirm that proximal tubular reabsorption of urine hepcidin-1 occurs in a megalin-dependent manner, whereas, in cardiac surgery patients, uncoupling of fractional excretion of hepcidin-25 and β2-microglobulin suggests local production of this peptide.
Losing weight and being lean are associated with poor declining health and progression of renal injury in diabetic nephropathy (DN) patients in China, whereas obese DN patients tend to have improved renal survival.
In chronic hemodialysis patients, the A736V TMPRSS6 genotype is associated with higher hepcidin levels and requirement for erythropoietin and anemia management, translating into clinical detectable differences that could be used to develop new approaches in anemia care.
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Sylvana de Mik et al. review animal models used in focal segmental glomerulosclerosis (FSGS) research and discuss how answers to the pathogenesis and cure for FSGS require the development of an animal model that resembles the human primary form of FSGS.BMC Nephrology 2013, 14:74
BMC Nephrology 2013, 14:107
BMC Nephrology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of kidney and associated disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
It is journal policy to publish work deemed by peer reviewers to be a coherent and sound addition to scientific knowledge and to put less emphasis on interest levels, provided that the research constitutes a useful contribution to the field.
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William Oetting is currently a Professor in the Departments of Experimental and Clinical Pharmacology in the College of Pharmacy and Genetics, Cell Biology and Development at in the MedicalSchool at the University of Minnesota. Professor Oetting's research focuses on the genetic analysis of common diseases. In particular, the effects of genetic variation on kidney allograft health and survival for kidney transplant recipients. As genetic variants associated with kidney function and/or disease are identified, they will become candidates for other diseases which include the kidney. He is also interested in identifying proteomic and metabolomics markers associated with kidney health after transplantation.
"I am pleased to have been involved with BMC Nephrology, first as an Associate Editor and now as Section Editor for the Genetics section. I have been impressed with the journal's high editorial standards, and rapidity of the peer review and publication process. Moreover, I strongly believe in the value of BMC Nephrology's open access policy, which makes new knowledge available to the global nephrology community, irrespective of institutional affiliation or financial means.
The genetics section of BMC Nephrology will provide a forum for investigators who are interested in genetic variation and their impact on kidney development, function, disease and response to therapy. Kidney disease is the ninth leading cause of death in the United States. The variability between individuals with kidney disease on overall health (e.g. glomerular diseases), or on kidney health (e.g. type 2 diabetes), shows why understanding the genetics of kidney disease is important. I am looking forward to the many contributions associated with the genetics of kidney health and disease that will be published in BMC Nephrology."