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Call for papers - Omics approaches in nephrology: from gene to protein

Guest Editors

Andrew Mallett, MBBS, MMed, PhD, CF, AFRACMA, FASN, FISN, FRCP, FRACP, James Cook University, Australia
Yun Miao, MD, PhD, Southern Medical University, China
John Andrew Sayer, MBChB, PhD, Newcastle University, UK

Submission Status: Open   |   Submission Deadline: 29 November 2024

BMC Nephrology seeks research using omics approaches to unravel the genetic basis of kidney diseases, identify novel biomarkers, and advance personalized medicine in nephrology. We invite researchers to contribute their work, shedding light on the molecular mechanisms underlying heritable kidney disorders and paving the way for improved diagnostics and targeted therapies.

New Content ItemThis Collection supports and amplifies research related to SDG 3: Good Health and Wellbeing.

Meet the Guest Editors

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Andrew John Mallett, MBBS, MMed, PhD, CF, AFRACMA, FASN, FISN, FRCP, FRACP, James Cook University, Australia

Dr Andrew John Mallett is a Professor of Medicine at James Cook University. He is an Adult Nephrologist with a special interest in genetic kidney disease and nephrogenetics.

Professor Mallett is a former Churchill Fellow, and he is currently a Queensland Health Advancing Clinical Research Fellow with a strongly emerging clinical and research profile in this field.

Professor Mallett is also National Director of the KidGen Collaborative, and, Director of Clinical Research and Nephrologist (Townsville University Hospital). He is committed to improving the understanding of genetic kidney disease as well as the clinical care and outcomes of patients and families affected by it.

Yun Miao, MD, PhD, Southern Medical University, China

Dr Yun Miao is a Professor and Associate Chief of the Department of Transplantation at Nanfang Hospital at the Southern Medical University.

Dr Miao is a clinician engaged in kidney transplantation surgery, donor organ refinement surgery, diagnosis and treatment of perioperative complications of transplant surgery, and long-term follow-up care after transplantation.

She is interested in the BK Polyomavirus infections, autosomal dominant polycystic kidney disease, and the immunological mechanisms of acute and chronic rejection after kidney transplantation.

John Andrew Sayer, MBChB, PhD, Newcastle University, UK

Professor John Sayer is a Professor of Renal Medicine at Newcastle University and Consultant Nephrologist at the Freeman Hospital’s Renal Services Centre. He has a particular interest in inherited kidney diseases and renal stone disease.

Professor Sayer’s clinical interests include a wide range of disorders including cystic kidney disease, Fabry disease, Alport syndrome, tubulopathies, and kidney stone disorders. He runs a regional renal genetics clinic and a family renal genetics clinic.

At a national level, Professor Sayer leads several Renal Rare Diseases Working Groups including ARPKD, Nephronophthisis, Autosomal Dominant Tubulointerstitial Kidney Disease, Fabry Disease, Mitochondrial Disease, Tubulopathies, Cystinuria, and Cystinosis.

Within Newcastle University, Professor Sayer’s laboratory studies focus on renal genetics, cystic kidney disease, renal ciliopathies, and renal stone formation. His work utilizes genetic techniques to investigate these conditions and find new therapies.

About the Collection

BMC Nephrology invites submissions to our Collection, Omics approaches in nephrology: from gene to protein.

Advances in omics technologies have revolutionized the field of nephrology, allowing for a comprehensive understanding of the genetic, epigenetic and proteomic aspects of various kidney-related disorders. This Collection gathers research that uses omics approaches, including genomics, transcriptomics, proteomics, and metabolomics, to elucidate the molecular mechanisms underlying heritable kidney diseases, biomarker discovery, and genetic or genomic testing in the context of renal disorders.

It is crucial to continue advancing our collective understanding of the kidney genome, gene expression, and biochemical composition to unravel the complex architecture of the kidney and identify novel biomarkers for early diagnosis and personalized treatment of pathologies. Recent advances and new technologies in omics have led to the identification of novel genetic variants associated with nephropathology, glomerular diseases, electrolyte disturbances, tubulointerstitial disorders, and congenital anomalies of kidneys and urinary tract (CAKUT). Additionally, omics-based studies have provided insights into the molecular pathways involved in kidney stone formation, nephrocalcinosis, and acute/chronic rejection of renal allograft.

Topics of interest include, but are not limited to:

  • Genetic or genomic testing and heritable causes of kidney diseases
  • Biomarker discovery in kidney disorders
  • Omics-based insights into kidney diseases
  • Molecular mechanisms of glomerular and tubulointersitial kidney diseases
  • Epigenetic regulation in kidney diseases
  • Transcriptomic profiling (single cell/nucleus, spatial, etc.) in nephrology and nephrogenetics
  • Integrative omics analysis for personalized treatment in nephrology
  • Mechanisms and biomarkers of renal allograft diseases, including acute and chronic rejection, recurrence of kidney disease after transplantation, and viral nephritis
  • Unique pathological changes and molecular patterns in renal allograft rejection
  • Mechanisms and signs of native kidney disease recurrence after transplantation

Image credit: Dr_Microbe /

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research Articles. Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Omics approaches in nephrology: from gene to protein" from the dropdown menu.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.