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	1. 2187 Accesses	Commentary A tutorial on pilot studies: the what, why and how Lehana Thabane, Jinhui Ma, Rong Chu, Ji Cheng, Afisi Ismaila, Lorena P Rios, Reid Robson, Marroon Thabane, Lora Giangregorio, Charles H Goldsmith BMC Medical Research Methodology 2010, 10:1 (6 January 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	2. 1575 Accesses	Research article Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews Beverley J Shea, Jeremy M Grimshaw, George A Wells, Maarten Boers, Neil Andersson, Candyce Hamel, Ashley C Porter, Peter Tugwell, David Moher, Lex M Bouter BMC Medical Research Methodology 2007, 7:10 (15 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	3. 1527 Accesses	Research article The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews Penny Whiting, Anne WS Rutjes, Johannes B Reitsma, Patrick MM Bossuyt, Jos Kleijnen BMC Medical Research Methodology 2003, 3:25 (10 November 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	4. 1374 Accesses	Commentary The case study approach Sarah Crowe, Kathrin Cresswell, Ann Robertson, Guro Huby, Anthony Avery, Aziz Sheikh BMC Medical Research Methodology 2011, 11:100 (27 June 2011) Abstract \| Full text \| PDF \| PubMed
	5. 1371 Accesses	Correspondence What is a pilot or feasibility study? A review of current practice and editorial policy Mubashir Arain, Michael J Campbell, Cindy L Cooper, Gillian A Lancaster BMC Medical Research Methodology 2010, 10:67 (16 July 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	6. 1203 Accesses	Research article The stepped wedge trial design: a systematic review Celia A Brown, Richard J Lilford BMC Medical Research Methodology 2006, 6:54 (8 November 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	7. 1165 Accesses	Correspondence How to do a grounded theory study: a worked example of a study of dental practices Alexandra Sbaraini, Stacy M Carter, R Evans, Anthony Blinkhorn BMC Medical Research Methodology 2011, 11:128 (9 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	8. 1161 Accesses	Research article Methods for the thematic synthesis of qualitative research in systematic reviews James Thomas, Angela Harden BMC Medical Research Methodology 2008, 8:45 (10 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	9. 1136 Accesses	Research article Views on the peer review system of biomedical journals: an online survey of academics from high-ranking universities Roger Chun-Man Ho, Kwok-Kei Mak, Ren Tao, Yanxia Lu, Jeffrey R Day, Fang Pan BMC Medical Research Methodology 2013, 13:74 (7 June 2013) Abstract \| Provisional PDF \| PubMed
	10. 1117 Accesses	Research article Estimating the mean and variance from the median, range, and the size of a sample Stela Hozo, Benjamin Djulbegovic, Iztok Hozo BMC Medical Research Methodology 2005, 5:13 (20 April 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Distribution free estimation of mean and variance for trials where the median, range and size are all that is reported should enable inclusion of more trials in meta-analysis.
	11. 1065 Accesses	Debate Methods for the synthesis of qualitative research: a critical review Elaine Barnett-Page, James Thomas BMC Medical Research Methodology 2009, 9:59 (11 August 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	12. 1022 Accesses	Research article The Hawthorne Effect: a randomised, controlled trial Rob McCarney, James Warner, Steve Iliffe, Robbert van Haselen, Mark Griffin, Peter Fisher BMC Medical Research Methodology 2007, 7:30 (3 July 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	13. 950 Accesses	Research article A systematic review of the content of critical appraisal tools Persis Katrak, Andrea E Bialocerkowski, Nicola Massy-Westropp, VS Saravana Kumar, Karen A Grimmer BMC Medical Research Methodology 2004, 4:22 (16 September 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Tools for the critical appraisal of research reports often lack information on their development and there is no gold standard for any type of study design.
	14. 892 Accesses	Research article The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials David Moher, Kenneth F Schulz, Douglas G Altman BMC Medical Research Methodology 2001, 1:2 (20 April 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	15. 863 Accesses	Research article Parametric versus non-parametric statistics in the analysis of randomized trials with non-normally distributed data Andrew J Vickers BMC Medical Research Methodology 2005, 5:35 (3 November 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 2 comments \| Editor’s summary Analysis of simulated data reveals that ANCOVA should be the preferred method for analyzing randomized trials with pre-test and post-test measures and non-normally distributed data, but in cases with extreme skew, Mann-Whitney was preferred.
	16. 851 Accesses	Research article Meta-analysis: Neither quick nor easy Nancy G Berman, Robert A Parker BMC Medical Research Methodology 2002, 2:10 (9 August 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17. 812 Accesses	Research article Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio Aluísio JD Barros, Vânia N Hirakata BMC Medical Research Methodology 2003, 3:21 (20 October 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	18. 808 Accesses	Correspondence Systematically reviewing and synthesizing evidence from conversation analytic and related discursive research to inform healthcare communication practice and policy: an illustrated guide Ruth H Parry, Victoria Land BMC Medical Research Methodology 2013, 13:69 (30 May 2013) Abstract \| Full text \| PDF \| ePUB \| PubMed
	19. 759 Accesses	Research article Methodology in conducting a systematic review of systematic reviews of healthcare interventions Valerie Smith, Declan Devane, Cecily M Begley, Mike Clarke BMC Medical Research Methodology 2011, 11:15 (3 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Locating and retrieving relevant literature when conducting a systematic review is challenging but a number of possible solutions are available which may help clinicians appraise published reviews systematically and aid evidence-based clinical decision-making.
	20. 718 Accesses	Research article Effectiveness of Pilates exercise in treating people with chronic low back pain: a systematic review of systematic reviews Cherie Wells, Gregory S Kolt, Paul Marshall, Bridget Hill, Andrea Bialocerkowski BMC Medical Research Methodology 2013, 13:7 (19 January 2013) Abstract \| Full text \| PDF \| PubMed
	21. 687 Accesses	Correspondence Reducing bias through directed acyclic graphs Ian Shrier, Robert W Platt BMC Medical Research Methodology 2008, 8:70 (30 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A simple 6-step approach to applying direct acyclic graphs in biomedical research may aid researchers to more accurately identify and adjust for multiple confounding effects and reduce the degree of bias better than traditional methods.
	22. 682 Accesses	Debate Qualitative description – the poor cousin of health research? Mette Neergaard, Frede Olesen, Rikke Andersen, Jens Sondergaard BMC Medical Research Methodology 2009, 9:52 (16 July 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23. 650 Accesses	Commentary Sample size calculations for cluster randomised controlled trials with a fixed number of clusters Karla Hemming, Alan J Girling, Alice J Sitch, Jennifer Marsh, Richard J Lilford BMC Medical Research Methodology 2011, 11:102 (30 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	24. 608 Accesses	Research article Risk of bias of randomized controlled trials published in orthopaedic journals Laura E Chess, Joel Gagnier BMC Medical Research Methodology 2013, 13:76 (9 June 2013) Abstract \| Provisional PDF \| PubMed
	25. 608 Accesses	Research article The use of percentage change from baseline as an outcome in a controlled trial is statistically inefficient: a simulation study Andrew J Vickers BMC Medical Research Methodology 2001, 1:6 (28 June 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central