- Timothy Beebe, Mayo Clinic College of Medicine
- Phil Edwards, London School of Hygiene & Tropical Medicine
- Chiu-Hsieh (Paul) Hsu, University of Arizona
- Vivian Welch, University of Ottawa
- Giulia Mangiameli, BioMed Central
An intervention for problem drinking reveals that trials with waiting list control conditions may overestimate treatment effects and that it may not be appropriate to assign participants actively ready to change to this study design.
Performance of the high-dimensional propensity score (hd-PS) algorithm to control for confounders in cohorts with small size or low outcome incidence may be improved through the aggregation of medication and medical diagnoses, using hierarchical coding systems.
Questioning methods and social context influence the detection of safety data during clinical trials and may preclude valid cross-trial comparisons indicating that alternative approaches, such as pictorial methods, may enhance communication of this information.
BMC Medical Research Methodology 2014, 14:30
BMC Medical Research Methodology is an open access, peer-reviewed journal that considers articles on methodological approaches to healthcare research. Articles on the methodology of epidemiological research, clinical trials and meta-analysis/systematic review are particularly encouraged, as are empirical studies of the associations between choice of methodology and study outcomes. BMC Medical Research Methodology does not aim to publish articles describing scientific methods or techniques: these should be directed to the BMC journal covering the relevant biomedical subject area.
It is journal policy to publish work deemed by peer reviewers to be a coherent and sound addition to scientific knowledge and to put less emphasis on interest levels, provided that the research constitutes a useful contribution to the field.
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