- Francisco Azuaje, Luxembourg Institute of Health
- Struan Grant, Children's Hospital of Philadelphia
- Patrick Tan, Graduate Medical School Singapore
- Pearlly Yan, The Ohio State University
- Tim Sands , BioMed Central
Transcriptome profiles of amniotic fluid collected at three gestational ages—second trimester, late preterm and full term—finds gene signatures that identify these stages and may also identify fetal organ maturity and predict illness in newborn infants.
Genomewide microRNA expression in placentas of women exposed to bisphenol A (BPA), a component of some plastics suspected of potentially being damaging to fetal development, shows increased miR-146a expression, providing a candidate biomarker to diagnose BPA contamination.
Responding to an acute need for trained medical genomics professionals, in a new course students can analyze their own personal genomes as a practical training tool, giving a direct insight into the psychosocial responses of patients too.
As genomic technology advances and more people access genomic information, terms describing DNA variation such as “mutation” and “polymorphism” are often becoming blurred; a new proposal originating from an online forum discussion recommends how to avoid confusion.
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- 30 September 2014
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BMC Medical Genomics is an open access, peer-reviewed journal that considers articles on all aspects of functional genomics, genome structure, genome-scale population genetics, epigenomics, proteomics, systems analysis, and pharmacogenomics in relation to human health and disease.
BMC Medical Genomics is part of the BMC series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. We offer an efficient, fair and friendly peer review service, and are committed to publishing all sound science, provided that there is some advance in knowledge presented by the work.
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Following posts in the UK, Australia, Iceland and Germany, Struan Grant has been the Associate Director of the Center for Applied Genomics at the Children's Hospital of Philadelphia since 2006. His current work focuses on metabolic disease, with a specific focus on pediatrics. Utilizing high-throughput genotyping technology, his goals include isolating genes involved in obesity and bone strength. Both of these phenotypes are known to be strongly determined by genetic factors and distillation of this component should be easier to determine in children, where the relatively short period of their lifetime limits the impact of environmental exposure.
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- 18 November 2015
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Volume 8 Suppl 3 (23 September 2015)
Selected articles from the IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2014): Medical Genomics
Belfast, UK. 2-5 November 2014
Volume 8 Suppl 2 (29 May 2015)
Selected articles from the 4th Translational Bioinformatics Conference and the 8th International Conference on Systems Biology (TBC/ISB 2014)
Qingdao, China. 24-27 October 2014