Section Editors

  • Francisco Azuaje, CRP-Santé
  • Struan Grant, Children's Hospital of Philadelphia
  • Patrick Tan, Graduate Medical School Singapore
  • Pearlly Yan, The Ohio State University

Executive Editor

  • Tim Sands , BioMed Central

Articles

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  • Image attributed to: iStock Photo

    New subtypes from existing prostate cancer signature

    Validation of an existing prostate cancer gene expression profile has identified two groups, associated with good or poor prognosis, rather than the previous four 4 subtypes, and highlights the importance of taking sample tissue composition into account.

    BMC Medical Genomics 2014, 7:50
  • Combining state-of-the-art methods pays off for PGS

    A combination of time-lapse monitoring of morphokinetic markers and array-CGH testing, results in improved rates of implantation and ongoing pregnancy for patients undergoing preimplantation genetic screening (PGS) over those in conventional incubators.

    BMC Medical Genomics 2014, 7:38
  • Image attributed to: Mate Marschalko, CCBY 2.0

    Blood will tell?

    A meta-analysis of brain studies shows that although a small proportion of eQTLs would be discovered by using blood as a surrogate for brain tissue, overlapping eQTLs are functionally similar, so  neurological and psychiatric studies using blood still have value.

    BMC Medical Genomics 2014, 7:31
  • Image attributed to: Mysi Ann on Flickr, CC BY-SA 2.0

    Dissection of psoriasis transcriptomes

    A meta-analysis of expression profiling and GWAS datasets in psoriasis, finds half the differentially expressed genes most highly expressed in skin cells, whereas GWAS candidates were most expressed in immune cells, particularly neutrophils.

    BMC Medical Genomics 2014, 7:27
  • Phenotypic approach to exome analysis

    A new program, PhenoVar, implements a phenotype-driven analysis of encrypted exome data in genetic diagnosis, circumventing some of the consent and ethical problems with incorporating exome sequencing in to the clinic.

    BMC Medical Genomics 2014, 7:22

Scope

BMC Medical Genomics is an open access, peer-reviewed journal that considers articles on all aspects of functional genomics, genome structure, genome-scale population genetics, epigenomics, proteomics, systems analysis, and pharmacogenomics in relation to human health and disease.

BMC Medical Genomics is part of the BMC series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. We offer an efficient, fair and friendly peer review service, and are committed to publishing all sound science, provided that there is some advance in knowledge presented by the work.

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Editor's profile

Struan Grant

Following posts in the UK, Australia, Iceland and Germany, Struan Grant has been the Associate Director of the Center for Applied Genomics at the Children's Hospital of Philadelphia since 2006. His current work focuses on metabolic disease, with a specific focus on pediatrics. Utilizing high-throughput genotyping technology, his goals include isolating genes involved in obesity and bone strength. Both of these phenotypes are known to be strongly determined by genetic factors and distillation of this component should be easier to determine in children, where the relatively short period of their lifetime limits the impact of environmental exposure.

Latest supplements

Volume 7 Suppl 1 (8 May 2014)

Selected articles from the 3rd Translational Bioinformatics Conference (TBC/ISCB-Asia 2013)

Research
Seoul, Korea. 2-4 October 2013

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ISSN: 1755-8794