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Editor-in-Chief Melissa Norton, MD
Medical Editor Jigisha Patel, MRCP PhD
In-house Editor Scott Edmunds PhD
Welcome to BMC Medical Genomics published by BioMed Central
BMC Medical Genomics is an open access journal publishing original peer-reviewed research articles in all aspects of functional genomics, genome structure, genome-scale population genetics, epigenomics, proteomics, systems analysis, and pharmacogenomics in relation to human health and disease.
BMC Medical Genomics (ISSN 1755-8794) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Thomson Reuters (ISI) and Google Scholar.
BMC Medical Genomics 2009, 2 :62
Treating lymphoblastic cell lines derived from schizophrenia patients with glucose deprivation and combining exon array, mRNA and genotyping analysis identifies stress related exon-specific expression changes and SNP variants potentially linked to this psychological disorder.
BMC Medical Genomics 2009, 2 :54
Combining global microRNA and mRNA expression data indicates MiR-125a is over-expressed in the liver of hyperglycaemic rats and is a putative modulator of glucose and lipid metabolism in a rat model of type 2 diabetes.
BMC Medical Genomics 2009, 2 :37
Activation of growth factor (GF) signalling contributes to the tamoxifen-insensitive estrogen receptor-positive breast cancer phenotype independent of human epidermal growth factor receptor (HER2) gene expression, suggesting an alternative therapeutic target for this aggressive disease.
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Research article
Gene expression profiling in sinonasal adenocarcinoma Dominique Tripodi, Sylvia Qu BMC Medical Genomics 2009, 2 :65 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Accurate molecular classification of cancer using simple rules Xiaosheng Wang, Osamu Gotoh BMC Medical Genomics 2009, 2 :64 (30 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Early over expression of messenger RNA for multiple genes, including insulin, in the Pancreatic Lymph Nodes of NOD mice is associated with Islet Autoimmunity B BMC Medical Genomics 2009, 2 :63 (2 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation Maureen V Martin, Brandi Rollins, P Adolfo Sequeira, Andrea Mes BMC Medical Genomics 2009, 2 :62 (22 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Discovering cancer genes by integrating network and functional properties Li Li, Kangyu Zhang, James Lee, Shaun Cordes, David P Davis, Zhijun Tang BMC Medical Genomics 2009, 2 :61 (19 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Transcriptional profiling differences for articular cartilage and repair tissue in equine joint surface lesions Michael J Mienaltowski, Liping Huang, David D Frisbie, C Wayne McIlwraith, Arnold J Stromberg, Arne C Bathke, James N MacLeod BMC Medical Genomics 2009, 2 :60 (14 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Gene expression meta-analysis supports existence of molecular apocrine breast cancer with a role for androgen receptor and implies interactions with ErbB family Sandeep Sanga, Bradley M Broom, Vittorio Cristini, Mary E Edgerton BMC Medical Genomics 2009, 2 :59 (11 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells Alissar Nehm BMC Medical Genomics 2009, 2 :58 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Evaluation of a new high-dimensional miRNA profiling platform Julie M Cunningham, Ann L Oberg, Pedro M Borralho, Betsy T Kren, Amy J French, Liang Wang, Brian M Bot, Bruce W Morlan, Kevin AT Silverstein, Rod Staggs, Yan Zeng, Anne-Francoise Lamblin, Christopher A Hilker, Jian-Bing Fan, Clifford J Steer, Stephen N Thibodeau BMC Medical Genomics 2009, 2 :57 (27 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Induction of the interleukin 6/ signal transducer and activator of transcription pathway in the lungs of mice sub-chronically exposed to mainstream tobacco smoke Sabina Halappanavar, Marsha Russell, Martin R Stampfli, Andrew Williams, Carole L Yauk BMC Medical Genomics 2009, 2 :56 (21 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Minireview
A role for neurotransmission and neurodevelopment in attention-deficit/hyperactivity disorder Tatiana Roman, Luis A Rohde, Mara H Hutz Genome Med 2009, 1 :107 (19 [Abstract ] [Full text ] [PDF ]
Research
Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq Mehdi Motallebipour, Adam Ameur, Madhu Sudhan Reddy Bysani, Kalicharan Patra, Ola Wallerman, Jonathan Mangion, Melissa A Barker, Kevin J McKernan, Jan Komorowski, Claes Wadelius Genome Biology 2009, 10 :R129 (17 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1
Erik Larsson, Peder Fredlund Fuchs, Johan Heldin, Irmeli Barkefors, Cecilia Bondjers, Guillem Genove, Christelle Arrondel, Par Gerwins, Christine Kurschat, Bernhard Schermer, Thomas Benzing, Scott J Harvey, Johan Kreuger, Per Lindahl Genome Medicine 2009, 1 :108 (16 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Short report
Genomic profiling of plasmablastic lymphoma using array comparative genomic hybridization (aCGH) : revealing significant overlapping genomic lesions with diffuse large B-cell lymphoma Chung-Che Chang, Xiaobo Zhou, Jesalyn J Taylor, Wan-Ting Huang, Xianwen Ren, Federico Monzon, Yongdong Feng, Pulivarthi H Rao, XinYan Lu, Facchetti Fabio, Susan Hilsenbeck, Chad J Creighton, Elaine S Jaffe, Ching-Ching Lau Journal of Hematology & Oncology 2009, 2 :47 (12 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Commentary
Reporting and evaluating genetic association studies Stephen P Peters Respiratory Research 2009, 10 :109 (12 [Abstract ] [Full Text ] [PDF ] [PubMed ] [Related articles ]
Research article
Insights into the pathogenesis of axial spondyloarthropathy based on gene expression profiles Srilakshmi M Sharma, Dongseok Choi, Stephen R Planck, Christina A Harrington, Carrie R Austin, Jinnell A Lewis, Tessa N Diebel, Tammy M Martin, Justine R Smith, James T Rosenbaum Arthritis Research & Therapy 2009, 11 :R168 (9 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Review
Pathophysiology of vascular dementia Francesco Iemolo MD, Giovanni Duro DR, Claudia Rizzo MD, Laura Castiglia DR, Vladimir Hachinski MD, Calogero Caruso MD Immunity & Ageing 2009, 6 :13 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Commentary
Multiple sclerosis: major histocompatibility complexity and antigen presentation Sreeram V Ramagopalan, George C Ebers Genome Med 2009, 1 :105 (6 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect Sean P Pitroda, Bassam T Wakim, Ravi F Sood, Mara G Beveridge, Michael A Beckett, Dhara M MacDermed, Ralph R Weichselbaum, Nikolai N Khodarev BMC Medicine 2009, 7 :68 (5 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Musings
Musings on genome medicine: Crohn's disease David G Nathan, Stuart H Orkin Genome Med 2009, 1 :103 (5 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
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