- Jonas Almeida, University of Alabama at Birmingham
- Struan Grant, Children's Hospital of Philadelphia
- Patrick Tan, Graduate Medical School Singapore
- Pearlly Yan, The Ohio State University
- Tim Sands , BioMed Central
Transcriptome profiles of patients undergoing haemodialysis show a different immune pattern compared to patients with chronic kidney disease without dialysis, although it cannot yet be ruled out that other confounding factors are responsible.
In a survey of perceptions of leukemia patients towards biobanking research ethics, majorities favoured one-time consent and retaining the right to withdrawal, and almost all favoured being informed of incidental findings relevant to their health.
Re-analysis of existing transcriptomic datasets from the brains of patients with HIV-associated neurocognitive impairment, using a systems biology approach, corroborates their results but also identifies possible co-expression networks linked to neurocognitive impairment in HIV and Alzheimer’s disease.
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BMC Medical Genomics is an open access, peer-reviewed journal that considers articles on all aspects of functional genomics, genome structure, genome-scale population genetics, epigenomics, proteomics, systems analysis, and pharmacogenomics in relation to human health and disease.
It is journal policy to publish work deemed by peer reviewers to be a coherent and sound addition to scientific knowledge and to put less emphasis on interest levels, provided that the research constitutes a useful contribution to the field.
Following posts in the UK, Australia, Iceland and Germany, Struan Grant has been the Associate Director of the Center for Applied Genomics at the Children's Hospital of Philadelphia since 2006. His current work focuses on metabolic disease, with a specific focus on pediatrics. Utilizing high-throughput genotyping technology, his goals include isolating genes involved in obesity and bone strength. Both of these phenotypes are known to be strongly determined by genetic factors and distillation of this component should be easier to determine in children, where the relatively short period of their lifetime limits the impact of environmental exposure.
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