- Peter-Bram 't Hoen, Leiden University Medical Center
- Shane C Burgess, University of Arizona
- David Burt, University of Edinburgh
- John K Colbourne, The University of Birmingham
- Ivo G Gut, Centro Nacional de Analisis Genomico, Barcelona
- Scott E Hemby, Wake Forest University
- Hans Lehrach, Max Planck Institute for Molecular Genetics
- David Lightfoot, Southern Illinois University at Carbondale
- Paul Pavlidis, University of British Columbia
- Daniel Sargent, Fondazione Edmund Mach - IASMA
- Leonard Schalkwyk, King's College London
- Fabiano Thompson, UFRJ
- Stefan Wiemann, German Cancer Research Center
- Derek Anane, BioMed Central
Understanding behavioural differences in feeding behaviour between organisms which share the same ecological niche can often be difficult to resolve. Genomic differences in sensory expression can go a long way to understanding what truly differentiates similar organisms.
iTRAQ protein quantification utilises isobaric reagents to identify and quantify expressed proteins in lysed cells. Characterisation of dynamic protein expression changes in cellular systems such as developing wheat grains, exhibits the potential of this novel technique.
miRNA regulate developmental processes in a variety of systems and at various stages of development. The presence of miRNAs in the milk of post-natal mother wallabies and neonates suggest their role may extend beyond the womb.
Beyond genome wide studies large scale phylum-wide studies can help to reveal the function and importance of distantly related gene clusters. This is particularly evident for genes involved in complex metabolic pathways such as cyanobacteria secondary metabolism.
PIRM syndrome casts a number of morbidities on finnish Ayrshire cattle including retardation and mortality. Following an exhaustive GWAS the syndrome has been traced to a G>A mutation caused by In frame exon skipping.
The genetic underpinnings of susceptibility to Klebsiella pneumonaie are poorly understood. Following a large scale QTL investigation utilising over 70 collaborative cross mice lines 3 loci have been identified important for susceptibility.
Zebrafish display a unique ability to regenerate heart tissue. In the present study, transcripts expressed in response to cardiac damage were identified using a range of techniques which may be useful in the future treatment of cardiac diseases.
Comparative analysis of genes from the recently discovered hemicellulose hydrolytic locus from Geobacillus have revealed a number of variances. This discovery provides a blueprint for the development of Geobacillus species able to degrade a wide variety of cellulose containing bio waste.
BMC Genomics 2015, 16(Suppl 3):S2
BMC Genomics is an open access, peer-reviewed journal that considers articles on all aspects of genome-scale analysis, functional genomics, and proteomics.
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