- Peter-Bram 't Hoen, Leiden University Medical Center
- Shane C Burgess, University of Arizona
- David Burt, University of Edinburgh
- John K Colbourne, The University of Birmingham
- Ivo G Gut, Centro Nacional de Analisis Genomico, Barcelona
- Scott E Hemby, Wake Forest University
- Hans Lehrach, Max Planck Institute for Molecular Genetics
- David Lightfoot, Southern Illinois University at Carbondale
- Paul Pavlidis, University of British Columbia
- Daniel Sargent, Fondazione Edmund Mach - IASMA
- Leonard Schalkwyk, King's College London
- Fabiano Thompson, UFRJ
- Stefan Wiemann, German Cancer Research Center
- Derek Anane, BioMed Central
iTRAQ protein quantification utilises isobaric reagents to identify and quantify expressed proteins in lysed cells. Characterisation of dynamic protein expression changes in cellular systems such as developing wheat grains, exhibits the potential of this novel technique.
miRNA regulate developmental processes in a variety of systems and at various stages of development. The presence of miRNAs in the milk of post-natal mother wallabies and neonates suggest their role may extend beyond the womb.
Beyond genome wide studies large scale phylum-wide studies can help to reveal the function and importance of distantly related gene clusters. This is particularly evident for genes involved in complex metabolic pathways such as cyanobacteria secondary metabolism.
PIRM syndrome casts a number of morbidities on finnish Ayrshire cattle including retardation and mortality. Following an exhaustive GWAS the syndrome has been traced to a G>A mutation caused by In frame exon skipping.
The genetic underpinnings of susceptibility to Klebsiella pneumonaie are poorly understood. Following a large scale QTL investigation utilising over 70 collaborative cross mice lines 3 loci have been identified important for susceptibility.
Zebrafish display a unique ability to regenerate heart tissue. In the present study, transcripts expressed in response to cardiac damage were identified using a range of techniques which may be useful in the future treatment of cardiac diseases.
Comparative analysis of genes from the recently discovered hemicellulose hydrolytic locus from Geobacillus have revealed a number of variances. This discovery provides a blueprint for the development of Geobacillus species able to degrade a wide variety of cellulose containing bio waste.
Giant spider crabs experience an increase in expression of stress related genes at intermediate ocean acidification levels whilst this effect is attenuated at higher levels. This may leave the species vulnerable to increasing ocean acidification.
BMC Genomics 2014, 15:972
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BMC Genomics is an open access, peer-reviewed journal that considers articles on all aspects of genome-scale analysis, functional genomics, and proteomics.
BMC Genomics is part of the BMC series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. We offer an efficient, fair and friendly peer review service, and are committed to publishing all sound science, provided that there is some advance in knowledge presented by the work.
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Volume 15 Suppl 8 (13 November 2014)
Selected articles from the 9th International Symposium on Bioinformatics Research and Applications (ISBRA-13): Genomics
Charlotte, NC, USA. 20-22 May 2013
Volume 15 Suppl 7 (27 October 2014)
Proceedings of the 9th International Conference of the Brazilian Association for Bioinformatics and Computational Biology (X-Meeting 2013)
Recife, Brazil. 3-6 November 2013
Volume 15 Suppl 6 (17 October 2014)
Proceedings of the Twelfth Annual Research in Computational Molecular Biology (RECOMB) Satellite Workshop on Comparative Genomics
Cold Spring Harbor, NY, USA. 19-22 October 2014