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51.

2059
Accesses

Research article   Open Access Highly Accessed

Genetic diversity and relationships in mulberry (genus Morus) as revealed by RAPD and ISSR marker assays

Arvind K Awasthi, GM Nagaraja, GV Naik, Sriramana Kanginakudru, K Thangavelu, Javaregowda Nagaraju BMC Genetics 2004, 5:1 (10 January 2004)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

52.

2059
Accesses

Research article   Open Access Highly Accessed

A comparison of statistical methods for genomic selection in a mice population

Haroldo HR Neves, Roberto Carvalheiro, Sandra A Queiroz BMC Genetics 2012, 13:100 (8 November 2012)

Abstract | Full text | PDF | PubMed | 1 comment

53.

2055
Accesses

Research article   Open Access Highly Accessed

SNP frequency, haplotype structure and linkage disequilibrium in elite maize inbred lines

Ada Ching, Katherine S Caldwell, Mark Jung, Maurine Dolan, Oscar Smith, Scott Tingey, Michele Morgante, Antoni J Rafalski BMC Genetics 2002, 3:19 (7 October 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

54.

2049
Accesses

Research article   Open Access Highly Accessed

Genotyping human ancient mtDNA control and coding region polymorphisms with a multiplexed Single-Base-Extension assay: the singular maternal history of the Tyrolean Iceman

Phillip Endicott, Juan J Sanchez, Irene Pichler, Paul Brotherton, Jerome Brooks, Eduard Egarter-Vigl, Alan Cooper, Peter Pramstaller BMC Genetics 2009, 10:29 (19 June 2009)

Abstract | Full text | PDF | PubMed

55.

2048
Accesses

Research article   Open Access Highly Accessed

Evolution and connectivity in the world-wide migration system of the mallard: Inferences from mitochondrial DNA

Robert HS Kraus, Anne Zeddeman, Pim van Hooft, Dmitry Sartakov, Sergei A Soloviev, Ronald C Ydenberg, Herbert HT Prins BMC Genetics 2011, 12:99 (17 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

56.

2031
Accesses

Research article   Open Access Highly Accessed

Genetic diversity of Phytophthora infestans in the Northern Andean region

Martha Cárdenas, Alejandro Grajales, Roberto Sierra, Alejandro Rojas, Adriana González-Almario, Angela Vargas, Mauricio Marín, Gustavo Fermín, Luz E Lagos, Niklaus J Grünwald, Adriana Bernal, Camilo Salazar, Silvia Restrepo BMC Genetics 2011, 12:23 (9 February 2011)

Abstract | Full text | PDF | PubMed

57.

1978
Accesses

Research article   Open Access Highly Accessed

Genomic microsatellites identify shared Jewish ancestry intermediate between Middle Eastern and European populations

Naama M Kopelman, Lewi Stone, Chaolong Wang, Dov Gefel, Marcus W Feldman, Jossi Hillel, Noah A Rosenberg BMC Genetics 2009, 10:80 (8 December 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Analysis of autosomal microsatellite loci in four Jewish populations shows a high level of similarity between them, and supports a largely Middle Eastern ancestry with varying degrees of admixture with European populations.

58.

1947
Accesses

Research article   Open Access Highly Accessed

Genome-wide linkage analyses identify Hfhl1 and Hfhl3 with frequency-specific effects on the hearing spectrum of NIH Swiss mice

James M Keller, Konrad Noben-Trauth BMC Genetics 2012, 13:32 (27 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

The identification of two quantitative trait loci (QTL) with frequency-specific effects on the hearing spectrum of NIH Swiss mice supports the hypothesis that frequency-specific hearing loss is the result of regionally specific gene activity in the cochlea.

59.

1933
Accesses

Research article   Open Access

A novel linkage map of sugarcane with evidence for clustering of retrotransposon-based markers

Alessandra C Palhares, Taislene B Rodrigues-Morais, Marie-Anne Van Sluys, Douglas S Domingues, Walter Maccheroni, Hamilton Jordão, Anete P Souza, Thiago G Marconi, Marcelo Mollinari, Rodrigo Gazaffi, Antonio Augusto F Garcia, Maria Lucia Vieira BMC Genetics 2012, 13:51 (28 June 2012)

Abstract | Full text | PDF | PubMed

60.

1896
Accesses

Research article   Open Access Highly Accessed

Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping

Adam B Olshen, Bert Gold, Kirk E Lohmueller, Jeffery P Struewing, Jaya Satagopan, Stefan A Stefanov, Eleazar Eskin, Tomas Kirchhoff, James A Lautenberger, Robert J Klein, Eitan Friedman, Larry Norton, Nathan A Ellis, Agnes Viale, Catherine S Lee, Patrick I Borgen, Andrew G Clark, Kenneth Offit, Jeff Boyd BMC Genetics 2008, 9:14 (5 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

61.

1891
Accesses

Research article   Open Access

Genetic dissection of growth, wood basic density and gene expression in interspecific backcrosses of Eucalyptus grandis and E. urophylla

Anand Raj Kullan, Maria M van Dyk, Charles A Hefer, Nicoletta Jones, Arnulf Kanzler, Alexander A Myburg BMC Genetics 2012, 13:60 (20 July 2012)

Abstract | Full text | PDF | PubMed

62.

1884
Accesses

Correspondence   Open Access Highly Accessed

Systems mapping of HIV-1 infection

Wei Hou, Yihan Sui, Zhong Wang, Yaqun Wang, Ningtao Wang, Jingyuan Liu, Yao Li, Maureen Goodenow, Li Yin, Zuoheng Wang, Rongling Wu BMC Genetics 2012, 13:91 (23 October 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Wei Hou and colleagues propose a conceptual statistical model to map the genetic control mechanisms of HIV viral dynamics during its progression to AIDS, offering a new way to chart the genetic architecture of viral infection.

63.

1877
Accesses

Research article   Open Access Highly Accessed

Genetic diversity and the emergence of ethnic groups in Central Asia

Evelyne Heyer, Patricia Balaresque, Mark A Jobling, Lluis Quintana-Murci, Raphaelle Chaix, Laure Segurel, Almaz Aldashev, Tanya Hegay BMC Genetics 2009, 10:49 (1 September 2009)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Turkic and Indo-Iranian populations show differences in paternal and maternally inherited genetic markers that suggest social boundaries to gene flow between ethnic groups have existed for a millennium, longer than expected from historical records.

64.

1867
Accesses

Software   Open Access Highly Accessed

GWAPower: a statistical power calculation software for genome-wide association studies with quantitative traits

Sheng Feng, Shengchu Wang, Chia-Cheng Chen, Lan Lan BMC Genetics 2011, 12:12 (21 January 2011)

Abstract | Full text | PDF | PubMed

65.

1864
Accesses

Research article   Open Access Highly Accessed

Comparative analysis of copy number variation detection methods and database construction

Asako Koike, Nao Nishida, Daiki Yamashita, Katsushi Tokunaga BMC Genetics 2011, 12:29 (7 March 2011)

Abstract | Full text | PDF | PubMed

66.

1855
Accesses

Research article   Open Access Highly Accessed

Efficiency of genomic selection using Bayesian multi-marker models for traits selected to reflect a wide range of heritabilities and frequencies of detected quantitative traits loci in mice

Dagmar NRG Kapell, Daniel Sorensen, Guosheng Su, Luc LG Janss, Cheryl J Ashworth, Rainer Roehe BMC Genetics 2012, 13:42 (31 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

67.

1847
Accesses

Research article   Open Access Highly Accessed

A missense mutation in growth differentiation factor 9 (GDF9) is strongly associated with litter size in sheep

Dag I Våge, Maren Husdal, Matthew P Kent, Gunnar Klemetsdal, Inger A Boman BMC Genetics 2013, 14:1 (2 January 2013)

Abstract | Full text | PDF | PubMed

68.

1837
Accesses

Research article   Open Access Highly Accessed

Genetic effects on coat colour in cattle: dilution of eumelanin and phaeomelanin pigments in an F2-Backcross Charolais × Holstein population

Beatriz Gutiérrez-Gil, Pamela Wiener, John L Williams BMC Genetics 2007, 8:56 (16 August 2007)

Abstract | Full text | PDF | PubMed

69.

1836
Accesses

Research article   Open Access Highly Accessed

A genome-wide association study using international breeding-evaluation data identifies major loci affecting production traits and stature in the Brown Swiss cattle breed

Jiazhong Guo, Hossein Jorjani, Örjan Carlborg BMC Genetics 2012, 13:82 (2 October 2012)

Abstract | Full text | PDF | PubMed

70.

1834
Accesses

Research article   Open Access Highly Accessed

RHD positive haplotypes in D negative Europeans

Franz F Wagner, Alexander Frohmajer, Willy A Flegel BMC Genetics 2001, 2:10 (16 July 2001)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

71.

1830
Accesses

Methodology article   Open Access

A complete classification of epistatic two-locus models

Ingileif B Hallgrímsdóttir, Debbie S Yuster BMC Genetics 2008, 9:17 (19 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment | F1000 Biology

72.

1827
Accesses

Research article   Open Access

Ascertaining gene flow patterns in livestock populations of developing countries: a case study in Burkina Faso goat

Amadou Traoré, Isabel Álvarez, Iván Fernández, Lucía Pérez-Pardal, Adama Kaboré, Gisèlle MS Ouédraogo-Sanou, Yacouba Zaré, Hamidou H Tambourá, Félix Goyache BMC Genetics 2012, 13:35 (7 May 2012)

Abstract | Full text | PDF | PubMed

73.

1795
Accesses

Research article   Open Access Highly Accessed

The powdery mildew resistance gene REN1 co-segregates with an NBS-LRR gene cluster in two Central Asian grapevines

Courtney Coleman, Dario Copetti, Guido Cipriani, Sarolta Hoffmann, Pál Kozma, László Kovács, Michele Morgante, Raffaele Testolin, Gabriele Di Gaspero BMC Genetics 2009, 10:89 (30 December 2009)

Abstract | Full text | PDF | PubMed

74.

1791
Accesses

Research article   Open Access Highly Accessed

Genetic evidence supports linguistic affinity of Mlabri - a hunter-gatherer group in Thailand

Shuhua Xu, Daoroong Kangwanpong, Mark Seielstad, Metawee Srikummool, Jatupol Kampuansai, Li Jin, The HUGO Pan-Asian SNP Consortium* BMC Genetics 2010, 11:18 (19 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

75.

1790
Accesses

Research article   Open Access Highly Accessed

ISSR markers show differentiation among Italian populations of Asparagus acutifolius L

Maria Sica, Graziella Gamba, Stefania Montieri, Luciano Gaudio, Serena Aceto BMC Genetics 2005, 6:17 (18 March 2005)

Abstract | Full text | PDF | PubMed

76.

1779
Accesses

Research article   Open Access Highly Accessed

Chicken meat quality: genetic variability and relationship with growth and muscle characteristics

Elisabeth Le Bihan-Duval, Martine Debut, Cécile M Berri, Nadine Sellier, Véronique Santé-Lhoutellier, Yves Jégo, Catherine Beaumont BMC Genetics 2008, 9:53 (18 August 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

77.

1771
Accesses

Research article   Open Access

Conservation of the COP9/signalosome in budding yeast

Susan Wee, Bettina Hetfeld, Wolfgang Dubiel, Dieter A Wolf BMC Genetics 2002, 3:15 (20 August 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The disruption of budding yeast genes that encode proteins interacting with a putative subunit of the COP9/signalosome provides evidence that this multiprotein complex is present and functional in budding yeast, as well as many metazoans.

78.

1768
Accesses

Research article   Open Access

Microsatellites reveal a strong subdivision of genetic structure in Chinese populations of the mite Tetranychus urticae Koch (Acari: Tetranychidae)

Jing-Tao Sun, Chunlan Lian, Maria Navajas, Xiao-Yue Hong BMC Genetics 2012, 13:8 (21 February 2012)

Abstract | Full text | PDF | PubMed

79.

1752
Accesses

Research article   Open Access Highly Accessed

Microsatellite-based phylogeny of Indian domestic goats

Pramod K Rout, Manjunath B Joshi, Ajoy Mandal, D Laloe, Lalji Singh, Kumarasamy Thangaraj BMC Genetics 2008, 9:11 (28 January 2008)

Abstract | Full text | PDF | PubMed

80.

1742
Accesses

Research article   Open Access

Genetic map of Triticum turgidum based on a hexaploid wheat population without genetic recombination for D genome

Li Zhang, Jiang-Tao Luo, Ming Hao, Lian-Quan Zhang, Zhong-Wei Yuan, Ze-Hong Yan, Ya-Xi Liu, Bo Zhang, Bao-Long Liu, Chun-Ji Liu, Huai-Gang Zhang, You-Liang Zheng, Deng-Cai Liu BMC Genetics 2012, 13:69 (13 August 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

81.

1738
Accesses

Research article   Open Access Highly Accessed

Culture creates genetic structure in the Caucasus: Autosomal, mitochondrial, and Y-chromosomal variation in Daghestan

Elizabeth E Marchani, W Scott Watkins, Kazima Bulayeva, Henry C Harpending, Lynn B Jorde BMC Genetics 2008, 9:47 (17 July 2008)

Abstract | Full text | PDF | PubMed | 1 comment

82.

1724
Accesses

Research article   Open Access Highly Accessed

An application of Random Forests to a genome-wide association dataset: Methodological considerations & new findings

Benjamin A Goldstein, Alan E Hubbard, Adele Cutler, Lisa F Barcellos BMC Genetics 2010, 11:49 (14 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology

83.

1716
Accesses

Research article   Open Access Highly Accessed

Chromosome differentiation patterns during cichlid fish evolution

Andréia B Poletto, Irani A Ferreira, Diogo C Cabral-de-Mello, Rafael T Nakajima, Juliana Mazzuchelli, Heraldo B Ribeiro, Paulo C Venere, Mauro Nirchio, Thomas D Kocher, Cesar Martins BMC Genetics 2010, 11:50 (15 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

84.

1714
Accesses

Research article   Open Access

The distribution of a germline methylation marker suggests a regional mechanism of LINE-1 silencing by the piRNA-PIWI system

Martin I Sigurdsson, Albert V Smith, Hans T Bjornsson, Jon J Jonsson BMC Genetics 2012, 13:31 (24 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Significantly high densities of methylation-associated SNPs flanking clusters of RNAs that interact with regulatory PIWI genes (piRNAs), supports the hypothesis that the piRNA-PIWI system preferentially methylates sequences in close proximity to the piRNA clusters

85.

1711
Accesses

Research article   Open Access Highly Accessed

Prevalence of common disease-associated variants in Asian Indians

Trevor J Pemberton, Niyati U Mehta, David Witonsky, Anna Di Rienzo, Hooman Allayee, David V Conti, Pragna I Patel BMC Genetics 2008, 9:13 (4 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

86.

1700
Accesses

Research article   Open Access Highly Accessed

Genetic affinities between the Yami tribe people of Orchid Island and the Philippine Islanders of the Batanes archipelago

Jun-Hun Loo, Jean A Trejaut, Ju-Chen Yen, Zong-Sian Chen, Chien-Liang Lee, Marie Lin BMC Genetics 2011, 12:21 (31 January 2011)

Abstract | Full text | PDF | PubMed

87.

1680
Accesses

Research article   Open Access

Spatial and temporal variation in population genetic structure of wild Nile tilapia (Oreochromis niloticus) across Africa

Etienne Bezault, Patricia Balaresque, Aboubacar Toguyeni, Yves Fermon, Hitoshi Araki, Jean-François Baroiller, Xavier Rognon BMC Genetics 2011, 12:102 (9 December 2011)

Abstract | Full text | PDF | PubMed

88.

1675
Accesses

Research article   Open Access Highly Accessed

SNP variation in the promoter of the PRKAG3 gene and association with meat quality traits in pig

Marion T Ryan, Ruth M Hamill, Aisling M O’Halloran, Grace C Davey, Jean McBryan, Anne M Mullen, Chris McGee, Marina Gispert, Olwen I Southwood, Torres Sweeney BMC Genetics 2012, 13:66 (25 July 2012)

Abstract | Full text | PDF | PubMed

89.

1675
Accesses

Research article   Open Access Highly Accessed

Assessment of clinical analytical sensitivity and specificity of next-generation sequencing for detection of simple and complex mutations

Ephrem LH Chin, Cristina da Silva, Madhuri Hegde BMC Genetics 2013, 14:6 (19 February 2013)

Abstract | Full text | PDF | PubMed

90.

1666
Accesses

Methodology article   Open Access Highly Accessed

Visualization of C. elegans transgenic arrays by GFP

Aidyl S Gonzalez-Serricchio, Paul W Sternberg BMC Genetics 2006, 7:36 (7 June 2006)

Abstract | Full text | PDF | PubMed

91.

1664
Accesses

Research article   Open Access

MHC polymorphism and disease resistance to vibrio anguillarum in 8 families of half-smooth tongue sole (Cynoglossus semilaevis)

Min Du, Song-lin Chen, Yan-hong Liu, Yang Liu, Jing-feng Yang BMC Genetics 2011, 12:78 (2 September 2011)

Abstract | Full text | PDF | PubMed | 1 comment

92.

1649
Accesses

Methodology article   Open Access Highly Accessed

Determining the effectiveness of High Resolution Melting analysis for SNP genotyping and mutation scanning at the TP53 locus

Sonia Garritano, Federica Gemignani, Catherine Voegele, Tú Nguyen-Dumont, Florence Le Calvez-Kelm, Deepika De Silva, Fabienne Lesueur, Stefano Landi, Sean V Tavtigian BMC Genetics 2009, 10:5 (17 February 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

93.

1640
Accesses

Research article   Open Access Highly Accessed

A missense mutation in PMEL17 is associated with the Silver coat color in the horse

Emma Brunberg, Leif Andersson, Gus Cothran, Kaj Sandberg, Sofia Mikko, Gabriella Lindgren BMC Genetics 2006, 7:46 (9 October 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The silver coat color dilution seen in horses, characterized as the Silver locus, is caused by a missense mutation in exon 11 of the equine PMEL17 gene.

94.

1636
Accesses

Research article   Open Access

Quantitative Trait Locus (QTL) meta-analysis and comparative genomics for candidate gene prediction in perennial ryegrass (Lolium perenne L.)

Hiroshi Shinozuka, Noel OI Cogan, German C Spangenberg, John W Forster BMC Genetics 2012, 13:101 (8 November 2012)

Abstract | Full text | PDF | PubMed

95.

1624
Accesses

Methodology article   Open Access Highly Accessed

Genotyping faecal samples of Bengal tiger Panthera tigris tigris for population estimation: A pilot study

Jyotsna Bhagavatula, Lalji Singh BMC Genetics 2006, 7:48 (17 October 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

96.

1617
Accesses

Research article   Open Access

Age modifies the genotype-phenotype relationship for the bitter receptor TAS2R38

Julie A Mennella, M Yanina Pepino, Fujiko F Duke, Danielle R Reed BMC Genetics 2010, 11:60 (1 July 2010)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Variation at the TAS2R38 locus is associated with bitter tasting ability; children with a heterozygous polymorphism in this taste receptor gene are more sensitive to bitterness than adults of the same haplotype.

97.

1615
Accesses

Research article   Open Access

Linkage disequilibrium and inbreeding estimation in Spanish Churra sheep

Elsa García-Gámez, Goutam Sahana, Beatriz Gutiérrez-Gil, Juan-Jose Arranz BMC Genetics 2012, 13:43 (12 June 2012)

Abstract | Full text | PDF | PubMed

98.

1611
Accesses

Research article   Open Access

Molecular ecology and selection in the drought-related Asr gene polymorphisms in wild and cultivated common bean (Phaseolus vulgaris L.)

Andrés J Cortés, M Chavarro, Santiago Madriñán, Dominique This, Matthew W Blair BMC Genetics 2012, 13:58 (16 July 2012)

Abstract | Full text | PDF | PubMed

99.

1603
Accesses

Research article   Open Access

Putative resistance gene markers associated with quantitative trait loci for fire blight resistance in Malus ‘Robusta 5’ accessions

Susan E Gardiner, John L Norelli, Nihal de Silva, Gennaro Fazio, Andreas Peil, Mickael Malnoy, Mary Horner, Deepa Bowatte, Charmaine Carlisle, Claudia Wiedow, Yizhen Wan, Carole L Bassett, Angela M Baldo, Jean-Marc Celton, Klaus Richter, Herb S Aldwinckle, Vincent GM Bus BMC Genetics 2012, 13:25 (3 April 2012)

Abstract | Full text | PDF | PubMed

100.

1600
Accesses

Research article   Open Access

Impacts of recent cultivation on genetic diversity pattern of a medicinal plant, Scutellaria baicalensis (Lamiaceae)

Qing-Jun Yuan, Zhi-Yong Zhang, Juan Hu, Lan-Ping Guo, Ai-Juan Shao, Lu-Qi Huang BMC Genetics 2010, 11:29 (29 April 2010)

Abstract | Full text | PDF | PubMed

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