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Cell signaling pathways and networks

This section will consider submissions on cell signaling, cell-cell interaction, second messenger systems and receptor-mediated signaling.

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1.

Research article   Open Access

The scaffolding protein GRASP/Tamalin directly binds to Dock180 as well as to cytohesins facilitating GTPase crosstalk in epithelial cell migration

Myriam A Attar, Lorraine C Santy BMC Cell Biology 2013, 14:9 (26 February 2013)

Abstract | Full text | PDF | PubMed

2.

Research article   Open Access

GxcC connects Rap and Rac signaling during Dictyostelium development

Katarzyna Plak, Douwe Veltman, Fabrizia Fusetti, Jetze Beeksma, Francisco Rivero, Peter JM Van Haastert, Arjan Kortholt BMC Cell Biology 2013, 14:6 (30 January 2013)

Abstract | Full text | PDF | ePUB | PubMed

3.

Research article   Open Access Highly Accessed

mTOR direct interactions with Rheb-GTPase and raptor: sub-cellular localization using fluorescence lifetime imaging

Rahul B Yadav, Pierre Burgos, Anthony W Parker, Valentina Iadevaia, Christopher G Proud, Rodger A Allen, James P O'Connell, Ananya Jeshtadi, Christopher D Stubbs, Stanley W Botchway BMC Cell Biology 2013, 14:3 (12 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Direct interaction of rapamycin (mTOR) with both Ras homologue enriched in brain (RheB) and regulatory associate protein of mTOR (raptor) identified in living cells using Fluorescence resonance energy transfer–fluorescence lifetime imaging (FRET-FLIM).  

4.

Research article   Open Access

Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes

Hiroki Matsui, Tomoyuki Yokoyama, Chie Tanaka, Hiroaki Sunaga, Norimichi Koitabashi, Takako Takizawa, Masashi Arai, Masahiko Kurabayashi BMC Cell Biology 2012, 13:37 (27 December 2012)

Abstract | Full text | PDF | PubMed

5.

Research article   Open Access

SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity

Robert Carrasquillo, Dequan Tian, Sneha Krishna, Martin R Pollak, Anna Greka, Johannes Schlöndorff BMC Cell Biology 2012, 13:33 (21 November 2012)

Abstract | Full text | PDF | PubMed

6.

Research article   Open Access

Dg-Dys-Syn1 signaling in Drosophila regulates the microRNA profile

April K Marrone, Evgeniia V Edeleva, Mariya M Kucherenko, Nai-Hua Hsiao, Halyna R Shcherbata BMC Cell Biology 2012, 13:26 (29 October 2012)

Abstract | Full text | PDF | PubMed

7.

Research article   Open Access

Secreted frizzled-related protein 4 expression is positively associated with responsiveness to Cisplatin of ovarian cancer cell lines in vitro and with lower tumour grade in mucinous ovarian cancers

Uttara Saran, Frank Arfuso, Nikolajs Zeps, Arunasalam Dharmarajan BMC Cell Biology 2012, 13:25 (8 October 2012)

Abstract | Full text | PDF | PubMed

8.

Research article   Open Access

Two glutamic acid residues in the DNA-binding domain are engaged in the release of STAT1 dimers from DNA

Verena Koch, Julia Staab, Volker Ruppert, Thomas Meyer BMC Cell Biology 2012, 13:22 (24 August 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Two glutamic acid residues in the DNA-binding domain adjacent to the DNA backbone sequence are crucial to the binding of STAT1(signal transducer and activator of transcription 1) dimers and transcriptional activation of cytokine driven target genes.

9.

Research article   Open Access

A potential role of the JNK pathway in hyperoxia-induced cell death, myofibroblast transdifferentiation and TGF-β1-mediated injury in the developing murine lung

Zhang Li, Rayman Choo-Wing, Huanxing Sun, Angara Sureshbabu, Reiko Sakurai, Virender K Rehan, Vineet Bhandari BMC Cell Biology 2011, 12:54 (15 December 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The c-JunNH2-terminal kinase (JNK) signaling pathway mediates, at least in part, hyperoxia-induced cell death, myofibroblast transdifferentiation and TGF-β1-mediated pulmonary injury, and may regulate these responses in the developing murine lung.

10.

Research article   Open Access Highly Accessed

SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells

Yu-Heng Lai, Jessica Cheng, Dongmei Cheng, Mattie E Feasel, Kyle D Beste, Junmin Peng, Asma Nusrat, Carlos S Moreno BMC Cell Biology 2011, 12:50 (19 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

11.

Research article   Open Access

The putative Notch ligand HyJagged is a transmembrane protein present in all cell types of adult Hydra and upregulated at the boundary between bud and parent

Andrea Prexl, Sandra Münder, Bernhard Loy, Elisabeth Kremmer, Susanne Tischer, Angelika Böttger BMC Cell Biology 2011, 12:38 (7 September 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

HyJagged, a Hydra transmembrane protein, shows homology with Jagged-like Notch ligands from other animals, is present in the same cells as Hydra Notch, and may be involved in the formation of the parent-bud boundary during budding.

12.

Research article   Open Access

Stanniocalcin 2 alters PERK signalling and reduces cellular injury during cerulein induced pancreatitis in mice

Elena N Fazio, Gabriel E DiMattia, Sami A Chadi, Kristin D Kernohan, Christopher L Pin BMC Cell Biology 2011, 12:17 (5 May 2011)

Abstract | Full text | PDF | PubMed

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