Mitotic phosphorylation of HDGF is critical for its mitogenic activity
Hepatoma-derived growth factor (HDGF) is phosphorylated during mitosis, leading to its activation as a mitogen. Immunostaining of paraformaldehyde -fixed COS-7 cells with an antibody specific for phospho-S103 HDGF demonstrates the presence of phosphorylated HDGF (red) in mitotic cells. Shown are cells that have undergone nuclear envelope breakdown and chromosomal condensation. The DNA was stained with DAPI (blue).
This information is for Figure 4, part A
Taken from: Allen Everett et al., 2011, BMC Cell Biology [View article]