Arp2/3 complex and vinculin in filopodia
After attachment to a fibronectin substrate, mouse embryonic fibroblasts produce filopodia, and staining for the actin-related Arp2/3 complex (green) and the focal-adhesion protein vinculin (red) showed numerous focal adhesions but little co-localization. Actin (blue) was labeled with rhodamine phalloidin, vinculin with a vinculin antibody and the Arp2/3 complex with an antibody to the p34-Arc subunit.
Taken from: Laura Machesky et al., 2008, BMC Cell Biology [View article]
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