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Research article   Open Access

Towards a theoretical understanding of false positives in DNA motif finding

Amin Zia, Alan M Moses BMC Bioinformatics 2012, 13:151 (27 June 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

A statistical approach to selecting and confirming validation targets in -omics experiments

Jeffrey T Leek, Margaret A Taub, Jason L Rasgon BMC Bioinformatics 2012, 13:150 (27 June 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access

PREMIM and EMIM: tools for estimation of maternal, imprinting and interaction effects using multinomial modelling

Richard Howey, Heather J Cordell BMC Bioinformatics 2012, 13:149 (27 June 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Surprising results on phylogenetic tree building methods based on molecular sequences

Gaston H Gonnet BMC Bioinformatics 2012, 13:148 (27 June 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Arrow plot: a new graphical tool for selecting up and down regulated genes and genes differentially expressed on sample subgroups

Carina Silva-Fortes, Maria Amaral Turkman, Lisete Sousa BMC Bioinformatics 2012, 13:147 (26 June 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access

Identifying mutation regions for closely related individuals without a known pedigree

Wenjuan Cui, Lusheng Wang BMC Bioinformatics 2012, 13:146 (25 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Error-correcting properties of the SOLiD Exact Call Chemistry

Tim Massingham, Nick Goldman BMC Bioinformatics 2012, 13:145 (22 June 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

Automated hierarchical classification of protein domain subfamilies based on functionally-divergent residue signatures

Andrew F Neuwald, Christopher J Lanczycki, Aron Marchler-Bauer BMC Bioinformatics 2012, 13:144 (22 June 2012)

Abstract | Full text | PDF | PubMed

Database   Open Access

QuartetS-DB: a large-scale orthology database for prokaryotes and eukaryotes inferred by evolutionary evidence

Chenggang Yu, Valmik Desai, Li Cheng, Jaques Reifman BMC Bioinformatics 2012, 13:143 (22 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Role of long- and short-range hydrophobic, hydrophilic and charged residues contact network in protein’s structural organization

Dhriti Sengupta, Sudip Kundu BMC Bioinformatics 2012, 13:142 (21 June 2012)

Abstract | Full text | PDF | PubMed

Database   Open Access

The M5nr: a novel non-redundant database containing protein sequences and annotations from multiple sources and associated tools

Andreas Wilke, Travis Harrison, Jared Wilkening, Dawn Field, Elizabeth M Glass, Nikos Kyrpides, Konstantinos Mavrommatis, Folker Meyer BMC Bioinformatics 2012, 13:141 (21 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Software   Open Access Highly Accessed

miREvo: an integrative microRNA evolutionary analysis platform for next-generation sequencing experiments

Ming Wen, Yang Shen, Suhua Shi, Tian Tang BMC Bioinformatics 2012, 13:140 (21 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Comparative study of classification algorithms for immunosignaturing data

Muskan Kukreja, Stephen Johnston, Phillip Stafford BMC Bioinformatics 2012, 13:139 (21 June 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access

EGNAS: an exhaustive DNA sequence design algorithm

Alfred Kick, Martin Bönsch, Michael Mertig BMC Bioinformatics 2012, 13:138 (20 June 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

A Bayesian model for classifying all differentially expressed proteins simultaneously in 2D PAGE gels

Steven H Wu, Michael A Black, Robyn A North, Allen G Rodrigo BMC Bioinformatics 2012, 13:137 (19 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Down-weighting overlapping genes improves gene set analysis

Adi Tarca, Sorin Draghici, Gaurav Bhatti, Roberto Romero BMC Bioinformatics 2012, 13:136 (19 June 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

β-empirical Bayes inference and model diagnosis of microarray data

Mohammad Hossain Mollah, M Haque Mollah, Hirohisa Kishino BMC Bioinformatics 2012, 13:135 (19 June 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

Jian Ye, George Coulouris, Irena Zaretskaya, Ioana Cutcutache, Steve Rozen, Thomas L Madden BMC Bioinformatics 2012, 13:134 (18 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Software   Open Access

Bios2mds: an R package for comparing orthologous protein families by metric multidimensional scaling

Julien Pelé, Jean-Michel Bécu, Hervé Abdi, Marie Chabbert BMC Bioinformatics 2012, 13:133 (15 June 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access

Simulating gene-gene and gene-environment interactions in complex diseases: Gene-Environment iNteraction Simulator 2

Michele Pinelli, Giovanni Scala, Roberto Amato, Sergio Cocozza, Gennaro Miele BMC Bioinformatics 2012, 13:132 (14 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Gene regulatory network modeling via global optimization of high-order dynamic Bayesian network

Nguyen Xuan, Madhu Chetty, Ross Coppel, Pramod P Wangikar BMC Bioinformatics 2012, 13:131 (13 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access

Bayesian model to detect phenotype-specific genes for copy number data

Juan R González, Carlos Abellán, Juan J Abellán BMC Bioinformatics 2012, 13:130 (13 June 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access

Fast and robust multiple sequence alignment with phylogeny-aware gap placement

Adam M Szalkowski BMC Bioinformatics 2012, 13:129 (13 June 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

ROCS: a Reproducibility Index and Confidence Score for Interaction Proteomics Studies

Jean-Eudes Dazard, Sudipto Saha, Rob M Ewing BMC Bioinformatics 2012, 13:128 (8 June 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

The language of gene ontology: a Zipf’s law analysis

Leila Kalankesh, Robert Stevens, Andy Brass BMC Bioinformatics 2012, 13:127 (7 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Identifying dysregulated pathways in cancers from pathway interaction networks

Ke-Qin Liu, Zhi-Ping Liu, Jin-Kao Hao, Luonan Chen, Xing-Ming Zhao BMC Bioinformatics 2012, 13:126 (7 June 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access

PollenCALC: Software for estimation of pollen compatibility of self-incompatible allo- and autotetraploid species

Andrea Aguirre, Bernd Wollenweber, Ursula K Frei, Thomas Lübberstedt BMC Bioinformatics 2012, 13:125 (7 June 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

BioWord: A sequence manipulation suite for Microsoft Word

Laura J Anzaldi, Daniel Muñoz-Fernández, Ivan Erill BMC Bioinformatics 2012, 13:124 (7 June 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access

Quartet decomposition server: a platform for analyzing phylogenetic trees

Fenglou Mao, David Williams, Olga Zhaxybayeva, Maria Poptsova, Pascal Lapierre, J Gogarten, Ying Xu BMC Bioinformatics 2012, 13:123 (7 June 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access

Web tools for large-scale 3D biological images and atlases

Zsolt L Husz, Nicholas Burton, Bill Hill, Nestor Milyaev, Richard A Baldock BMC Bioinformatics 2012, 13:122 (7 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Detection of identity by descent using next-generation whole genome sequencing data

Shu-Yi Su, Jay Kasberger, Sergio Baranzini, William Byerley, Wilson Liao, Jorge Oksenberg, Elliott Sherr, Eric Jorgenson BMC Bioinformatics 2012, 13:121 (6 June 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies

Ann-Kristin Petersen, Jan Krumsiek, Brigitte Wägele, Fabian J Theis, H-Erich Wichmann, Christian Gieger, Karsten Suhre BMC Bioinformatics 2012, 13:120 (6 June 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Biomine: predicting links between biological entities using network models of heterogeneous databases

Lauri Eronen, Hannu Toivonen BMC Bioinformatics 2012, 13:119 (6 June 2012)

Abstract | Full text | PDF | PubMed | 1 comment

Research article   Open Access

Predicting protein-ATP binding sites from primary sequence through fusing bi-profile sampling of multi-view features

Ya-Nan Zhang, Dong-Jun Yu, Shu-Sen Li, Yong-Xian Fan, Yan Huang, Hong-Bin Shen BMC Bioinformatics 2012, 13:118 (31 May 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

MergeAlign: improving multiple sequence alignment performance by dynamic reconstruction of consensus multiple sequence alignments

Peter W Collingridge, Steven Kelly BMC Bioinformatics 2012, 13:117 (30 May 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access

OLSVis: an animated, interactive visual browser for bio-ontologies

Steven Vercruysse, Aravind Venkatesan, Martin Kuiper BMC Bioinformatics 2012, 13:116 (30 May 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access

PyMS: a Python toolkit for processing of gas chromatography-mass spectrometry (GC-MS) data. Application and comparative study of selected tools

Sean O'Callaghan, David P De Souza, Andrew Isaac, Qiao Wang, Luke Hodkinson, Moshe Olshansky, Tim Erwin, Bill Appelbe, Dedreia L Tull, Ute Roessner, Antony Bacic, Malcolm J McConville, Vladimir A Likić BMC Bioinformatics 2012, 13:115 (30 May 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Detection and correction of probe-level artefacts on microarrays

Tobias Petri, Evi Berchtold, Ralf Zimmer, Caroline C Friedel BMC Bioinformatics 2012, 13:114 (30 May 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Molecular ecological network analyses

Ye Deng, Yi-Huei Jiang, Yunfeng Yang, Zhili He, Feng Luo, Jizhong Zhou BMC Bioinformatics 2012, 13:113 (30 May 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs

Suleiman A Khan, Ali Faisal, John Mpindi, Juuso A Parkkinen, Tuomo Kalliokoski, Antti Poso, Olli P Kallioniemi, Krister Wennerberg, Samuel Kaski BMC Bioinformatics 2012, 13:112 (30 May 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

MetaDisorder: a meta-server for the prediction of intrinsic disorder in proteins

Lukasz P Kozlowski, Janusz M Bujnicki BMC Bioinformatics 2012, 13:111 (24 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Software   Open Access Highly Accessed

TreeSnatcher plus: capturing phylogenetic trees from images

Thomas Laubach, Arndt von Haeseler, Martin J Lercher BMC Bioinformatics 2012, 13:110 (24 May 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Towards the identification of protein complexes and functional modules by integrating PPI network and gene expression data

Min Li, Xuehong Wu, Jianxin Wang, Yi Pan BMC Bioinformatics 2012, 13:109 (23 May 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Extracting semantically enriched events from biomedical literature

Makoto Miwa, Paul Thompson, John McNaught, Douglas B Kell, Sophia Ananiadou BMC Bioinformatics 2012, 13:108 (23 May 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Learning Sparse Representations for Fruit-Fly Gene Expression Pattern Image Annotation and Retrieval

Lei Yuan, Alexander Woodard, Shuiwang Ji, Yuan Jiang, Zhi-Hua Zhou, Sudhir Kumar, Jieping Ye BMC Bioinformatics 2012, 13:107 (23 May 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

Natural product-likeness score revisited: an open-source, open-data implementation

Kalai Vanii, Pablo Moreno, Andreas Truszkowski, Peter Ertl, Christoph Steinbeck BMC Bioinformatics 2012, 13:106 (20 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Software   Open Access

Multiple structure alignment with msTALI

Paul Shealy, Homayoun Valafar BMC Bioinformatics 2012, 13:105 (20 May 2012)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Profile-based short linear protein motif discovery

Niall J Haslam, Denis C Shields BMC Bioinformatics 2012, 13:104 (18 May 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

rCUR: an R package for CUR matrix decomposition

András Bodor, István Csabai, Michael W Mahoney, Norbert Solymosi BMC Bioinformatics 2012, 13:103 (17 May 2012)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

Workflows for microarray data processing in the Kepler environment

Thomas Stropp, Timothy McPhillips, Bertram Ludäscher, Mark Bieda BMC Bioinformatics 2012, 13:102 (17 May 2012)

Abstract | Full text | PDF | PubMed

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