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Page 15 of 86

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Research article   Open Access

Differential C3NET reveals disease networks of direct physical interactions

Gökmen Altay, Mohammad Asim, Florian Markowetz, David E Neal BMC Bioinformatics 2011, 12:296 (21 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

ADAM: Analysis of Discrete Models of Biological Systems Using Computer Algebra

Franziska Hinkelmann, Madison Brandon, Bonny Guang, Rustin McNeill, Grigoriy Blekherman, Alan Veliz-Cuba, Reinhard Laubenbacher BMC Bioinformatics 2011, 12:295 (20 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Multi-target QSAR modelling in the analysis and design of HIV-HCV co-inhibitors: an in-silico study

Qi Liu, Han Zhou, Lin Liu, Xi Chen, Ruixin Zhu, Zhiwei Cao BMC Bioinformatics 2011, 12:294 (20 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access Highly Accessed

FAAST: Flow-space Assisted Alignment Search Tool

Fredrik Lysholm, Björn Andersson, Bengt Persson BMC Bioinformatics 2011, 12:293 (19 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Unraveling gene regulatory networks from time-resolved gene expression data -- a measures comparison study

Sabrina Hempel, Aneta Koseska, Zoran Nikoloski, Jürgen Kurths BMC Bioinformatics 2011, 12:292 (19 July 2011)

Abstract | Full text | PDF | PubMed

Software   Open Access

Inferring signalling networks from longitudinal data using sampling based approaches in the R-package 'ddepn'

Christian Bender, Silvia Heyde, Frauke Henjes, Stefan Wiemann, Ulrike Korf, Tim Beißbarth BMC Bioinformatics 2011, 12:291 (19 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Bias detection and correction in RNA-Sequencing data

Wei Zheng, Lisa M Chung, Hongyu Zhao BMC Bioinformatics 2011, 12:290 (19 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Software   Open Access Highly Accessed

Bio::Homology::InterologWalk - A Perl module to build putative protein-protein interaction networks through interolog mapping

Giuseppe Gallone, T Ian Simpson, J Douglas Armstrong, Andrew P Jarman BMC Bioinformatics 2011, 12:289 (18 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Reporting FDR analogous confidence intervals for the log fold change of differentially expressed genes

Klaus Jung, Tim Friede, Tim Beißbarth BMC Bioinformatics 2011, 12:288 (15 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Statistical Mutation Calling from Sequenced Overlapping DNA Pools in TILLING Experiments

Victor Missirian, Luca Comai, Vladimir Filkov BMC Bioinformatics 2011, 12:287 (14 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Software   Open Access

Construct and Compare Gene Coexpression Networks with DAPfinder and DAPview

Jeff Skinner, Yuri Kotliarov, Sudhir Varma, Karina L Mine, Anatoly Yambartsev, Richard Simon, Yentram Huyen, Andrey Morgun BMC Bioinformatics 2011, 12:286 (14 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

S3QL: A distributed domain specific language for controlled semantic integration of life sciences data

Helena F Deus, Miriã C Correa, Romesh Stanislaus, Maria Miragaia, Wolfgang Maass, Hermínia de Lencastre, Ronan Fox, Jonas S Almeida BMC Bioinformatics 2011, 12:285 (14 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access

Modeling measurement error in tumor characterization studies

Cyril Rakovski, Daniel J Weisenberger, Paul Marjoram, Peter W Laird, Kimberly D Siegmund BMC Bioinformatics 2011, 12:284 (13 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Improving the performance of β-turn prediction using predicted shape strings and a two-layer support vector machine model

Zehui Tang, Tonghua Li, Rida Liu, Wenwei Xiong, Jiangming Sun, Yaojuan Zhu, Guanyan Chen BMC Bioinformatics 2011, 12:283 (13 July 2011)

Abstract | Full text | PDF | PubMed

Database   Open Access Highly Accessed

Algal Functional Annotation Tool: a web-based analysis suite to functionally interpret large gene lists using integrated annotation and expression data

David Lopez, David Casero, Shawn J Cokus, Sabeeha S Merchant, Matteo Pellegrini BMC Bioinformatics 2011, 12:282 (12 July 2011)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

A novel method to identify cooperative functional modules: study of module coordination in the Saccharomyces cerevisiae cell cycle

Jeh-Ting Hsu, Chien-Hua Peng, Wen-Ping Hsieh, Chung-Yu Lan, Chuan Tang BMC Bioinformatics 2011, 12:281 (12 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

DECK: Distance and environment-dependent, coarse-grained, knowledge-based potentials for protein-protein docking

Shiyong Liu, Ilya A Vakser BMC Bioinformatics 2011, 12:280 (11 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Detection of Fused Genes in Eukaryotic Genomes using Gene deFuser: Analysis of the Tetrahymena thermophila genome

Hannah MW Salim, Amanda M Koire, Nicholas A Stover, Andre RO Cavalcanti BMC Bioinformatics 2011, 12:279 (11 July 2011)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

ReadDB Provides Efficient Storage for Mapped Short Reads

P Alexander Rolfe, David K Gifford BMC Bioinformatics 2011, 12:278 (7 July 2011)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

An integrated ChIP-seq analysis platform with customizable workflows

Eugenia G Giannopoulou, Olivier Elemento BMC Bioinformatics 2011, 12:277 (7 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Quantitative characterization and analysis of the dynamic NF-κB response in microglia

Patrick W Sheppard, Xiaoyun Sun, John F Emery, Rona G Giffard, Mustafa Khammash BMC Bioinformatics 2011, 12:276 (5 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

AlignHUSH: Alignment of HMMs using structure and hydrophobicity information

Oruganty Krishnadev, Narayanaswamy Srinivasan BMC Bioinformatics 2011, 12:275 (5 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Detection of lineage-specific evolutionary changes among primate species

Mihaela Pertea, Geo M Pertea, Steven L Salzberg BMC Bioinformatics 2011, 12:274 (4 July 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

DivE (Divergence by Evolution), a new methodology for predicting both positive and negative selection in noncoding DNA, is particularly well-suited to detecting lineage-specific selection in large genomes as demonstrated using primate species

Methodology article   Open Access Highly Accessed

Gene set analysis for longitudinal gene expression data

Ke Zhang, Haiyan Wang, Arne C Bathke, Solomon W Harrar, Hans-Peter Piepho, Youping Deng BMC Bioinformatics 2011, 12:273 (3 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access Highly Accessed

Improving pan-genome annotation using whole genome multiple alignment

Samuel V Angiuoli, Julie C Dunning Hotopp, Steven L Salzberg, Hervé Tettelin BMC Bioinformatics 2011, 12:272 (30 June 2011)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

DNACLUST: accurate and efficient clustering of phylogenetic marker genes

Mohammadreza Ghodsi, Bo Liu, Mihai Pop BMC Bioinformatics 2011, 12:271 (30 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Predicting mutually exclusive spliced exons based on exon length, splice site and reading frame conservation, and exon sequence homology

Holger Pillmann, Klas Hatje, Florian Odronitz, Björn Hammesfahr, Martin Kollmar BMC Bioinformatics 2011, 12:270 (30 June 2011)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

Network-based group variable selection for detecting expression quantitative trait loci (eQTL)

Weichen Wang, Xuegong Zhang BMC Bioinformatics 2011, 12:269 (30 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

New words in human mutagenesis

Alexander Y Panchin, Sergey I Mitrofanov, Andrei V Alexeevski, Sergey A Spirin, Yuri V Panchin BMC Bioinformatics 2011, 12:268 (30 June 2011)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

SeqGene: a comprehensive software solution for mining exome- and transcriptome- sequencing data

Xutao Deng BMC Bioinformatics 2011, 12:267 (29 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Software   Open Access

DOSim: An R package for similarity between diseases based on Disease Ontology

Jiang Li, Binsheng Gong, Xi Chen, Tao Liu, Chao Wu, Fan Zhang, Chunquan Li, Xiang Li, Shaoqi Rao, Xia Li BMC Bioinformatics 2011, 12:266 (29 June 2011)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

phenosim - A software to simulate phenotypes for testing in genome-wide association studies

Torsten Günther, Inka Gawenda, Karl J Schmid BMC Bioinformatics 2011, 12:265 (29 June 2011)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

MAVENs: Motion analysis and visualization of elastic networks and structural ensembles

Michael T Zimmermann, Andrzej Kloczkowski, Robert L Jernigan BMC Bioinformatics 2011, 12:264 (28 June 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

MAVEN is a new software suite for generating elastic network models from raw program database files or density maps, and is able to integrate model generation, evaluation, analysis and visualization into a user-friendly environment.

Research article   Open Access

Characterization of a Bayesian genetic clustering algorithm based on a Dirichlet process prior and comparison among Bayesian clustering methods

Akio Onogi, Masanobu Nurimoto, Mitsuo Morita BMC Bioinformatics 2011, 12:263 (28 June 2011)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

A mutation degree model for the identification of transcriptional regulatory elements

Changqing Zhang, Jin Wang, Xu Hua, Jinggui Fang, Huaiqiu Zhu, Xiang Gao BMC Bioinformatics 2011, 12:262 (27 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

PlantPhos: using maximal dependence decomposition to identify plant phosphorylation sites with substrate site specificity

Tzong-Yi Lee, Neil Bretaña, Cheng-Tsung Lu BMC Bioinformatics 2011, 12:261 (26 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access

Computable visually observed phenotype ontological framework for plants

Jaturon Harnsomburana, Jason M Green, Adrian S Barb, Mary Schaeffer, Leszek Vincent, Chi-Ren Shyu BMC Bioinformatics 2011, 12:260 (24 June 2011)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

AMDORAP: Non-targeted metabolic profiling based on high-resolution LC-MS

Hiroki Takahashi, Takuya Morimoto, Naotake Ogasawara, Shigehiko Kanaya BMC Bioinformatics 2011, 12:259 (24 June 2011)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

Cell subset prediction for blood genomic studies

Christopher R Bolen, Mohamed Uduman, Steven H Kleinstein BMC Bioinformatics 2011, 12:258 (24 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

BioAssay Ontology (BAO): a semantic description of bioassays and high-throughput screening results

Ubbo Visser, Saminda Abeyruwan, Uma Vempati, Robin P Smith, Vance Lemmon, Stephan C Schürer BMC Bioinformatics 2011, 12:257 (24 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Semantic inference using chemogenomics data for drug discovery

Qian Zhu, Yuyin Sun, Sashikiran Challa, Ying Ding, Michael S Lajiness, David J Wild BMC Bioinformatics 2011, 12:256 (23 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access

Study of large and highly stratified population datasets by combining iterative pruning principal component analysis and structure

Tulaya Limpiti, Apichart Intarapanich, Anunchai Assawamakin, Philip J Shaw, Pongsakorn Wangkumhang, Jittima Piriyapongsa, Chumpol Ngamphiw, Sissades Tongsima BMC Bioinformatics 2011, 12:255 (23 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access Highly Accessed

Fusion of metabolomics and proteomics data for biomarkers discovery: case study on the experimental autoimmune encephalomyelitis

Lionel Blanchet, Agnieszka Smolinska, Amos Attali, Marcel P Stoop, Kirsten AM Ampt, Hans van Aken, Ernst Suidgeest, Tinka Tuinstra, Sybren S Wijmenga, Theo Luider, Lutgarde MC Buydens BMC Bioinformatics 2011, 12:254 (22 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems

Kim-Anh Lê Cao, Simon Boitard, Philippe Besse BMC Bioinformatics 2011, 12:253 (22 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Computational study of noise in a large signal transduction network

Jukka Intosalmi, Tiina Manninen, Keijo Ruohonen, Marja-Leena Linne BMC Bioinformatics 2011, 12:252 (21 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Determinants of antigenicity and specificity in immune response for protein sequences

Yulong Wang, Wenjun Wu, Nicolas N Negre, Kevin P White, Cheng Li, Parantu K Shah BMC Bioinformatics 2011, 12:251 (21 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

NORMA-Gene: A simple and robust method for qPCR normalization based on target gene data

Lars-Henrik Heckmann, Peter B Sørensen, Paul Krogh, Jesper G Sørensen BMC Bioinformatics 2011, 12:250 (21 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Deregulation upon DNA damage revealed by joint analysis of context-specific perturbation data

Ewa Szczurek, Florian Markowetz, Irit Gat-Viks, Przemysław Biecek, Jerzy Tiuryn, Martin Vingron BMC Bioinformatics 2011, 12:249 (21 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

PhyloMap: an algorithm for visualizing relationships of large sequence data sets and its application to the influenza A virus genome

Jiajie Zhang, Amir Mamlouk, Thomas Martinetz, Suhua Chang, Jing Wang, Rolf Hilgenfeld BMC Bioinformatics 2011, 12:248 (20 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Dissecting protein loops with a statistical scalpel suggests a functional implication of some structural motifs

Leslie Regad, Juliette Martin, Anne-Claude Camproux BMC Bioinformatics 2011, 12:247 (20 June 2011)

Abstract | Full text | PDF | PubMed

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