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Volume 14 (2013) - March 2013

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Methodology article   Open Access Highly Accessed

PlanktoVision – an automated analysis system for the identification of phytoplankton

Katja Schulze, Ulrich M Tillich, Thomas Dandekar, Marcus Frohme BMC Bioinformatics 2013, 14:115 (27 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Computing minimal nutrient sets from metabolic networks via linear constraint solving

Steven Eker, Markus Krummenacker, Alexander G Shearer, Ashish Tiwari, Ingrid M Keseler, Carolyn Talcott, Peter D Karp BMC Bioinformatics 2013, 14:114 (27 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Methodology article   Open Access Highly Accessed

Using cited references to improve the retrieval of related biomedical documents

Francisco M Ortuño, Ignacio Rojas, Miguel A Andrade-Navarro, Jean-Fred Fontaine BMC Bioinformatics 2013, 14:113 (27 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

A systematic comparison of the MetaCyc and KEGG pathway databases

Tomer Altman, Michael Travers, Anamika Kothari, Ron Caspi, Peter D Karp BMC Bioinformatics 2013, 14:112 (27 March 2013)

Abstract | Provisional PDF | PubMed

Database   Open Access Highly Accessed

A benchmark server using high resolution protein structure data, and benchmark results for membrane helix predictions

Emma M Rath, Dominique Tessier, Alexander A Campbell, Hong Ching Lee, Tim Werner, Noeris K Salam, Lawrence K Lee, W Bret Church BMC Bioinformatics 2013, 14:111 (27 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Methodology article   Open Access Highly Accessed

Differential expression analysis for paired RNA-seq data

Lisa M Chung, John P Ferguson, Wei Zheng, Feng Qian, Vincent Bruno, Ruth R Montgomery, Hongyu Zhao BMC Bioinformatics 2013, 14:110 (27 March 2013)

Abstract | Provisional PDF | PubMed

Software   Open Access Highly Accessed

TPMS: a set of utilities for querying collections of gene trees

Thomas Bigot, Vincent Daubin, Florent Lassalle, Guy Perrière BMC Bioinformatics 2013, 14:109 (27 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Methodology article   Open Access Highly Accessed

LASAGNA: A novel algorithm for transcription factor binding site alignment

Chih Lee, Chun-Hsi Huang BMC Bioinformatics 2013, 14:108 (24 March 2013)

Abstract | Provisional PDF | PubMed

Methodology article   Open Access Highly Accessed

Non-negative matrix factorization by maximizing correntropy for cancer clustering

Jim Jing-Yan Wang, Xiaolei Wang, Xin Gao BMC Bioinformatics 2013, 14:107 (24 March 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

SMOTE for high-dimensional class-imbalanced data

Rok Blagus, Lara Lusa BMC Bioinformatics 2013, 14:106 (22 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Software   Open Access Highly Accessed

SDM-Assist software to design site-directed mutagenesis primers introducing “silent” restriction sites

Abhijit Karnik, Rucha Karnik, Christopher Grefen BMC Bioinformatics 2013, 14:105 (22 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Methodology article   Open Access Highly Accessed

Application of text-mining for updating protein post-translational modification annotation in UniProtKB

Anne-Lise Veuthey, Alan Bridge, Julien Gobeill, Patrick Ruch, Johanna R McEntyre, Lydie Bougueleret, Ioannis Xenarios BMC Bioinformatics 2013, 14:104 (22 March 2013)

Abstract | Full text | PDF | PubMed

Correspondence   Open Access Highly Accessed

The Enzyme Portal: a case study in applying user-centred design methods in bioinformatics

Paula de Matos, Jennifer A Cham, Hong Cao, Rafael Alcántara, Francis Rowland, Rodrigo Lopez, Christoph Steinbeck BMC Bioinformatics 2013, 14:103 (20 March 2013)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

The first ‘how to’ guide for applying User-Centred Design (UCD) to websites for bioinformatics involves biomedical researchers rather than developers to design better web experiences, for example The Enzyme Portal

Research article   Open Access Highly Accessed

Mobilomics in Saccharomyces cerevisiae strains

Giulia Menconi, Giovanni Battaglia, Roberto Grossi, Nadia Pisanti, Roberto Marangoni BMC Bioinformatics 2013, 14:102 (20 March 2013)

Abstract | Provisional PDF | PubMed

Methodology article   Open Access Highly Accessed

Adaptive filtering of microarray gene expression data based on Gaussian mixture decomposition

Michal Marczyk, Roman Jaksik, Andrzej Polanski, Joanna Polanska BMC Bioinformatics 2013, 14:101 (20 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Gene expression profiling of breast cancer survivability by pooled cDNA microarray analysis using logistic regression, artificial neural networks and decision trees

Hsiu-Ling Chou, Chung-Tay Yao, Sui-Lun Su, Chia-Yi Lee, Kuang-Yu Hu, Harn-Jing Terng, Yun-Wen Shih, Yu-Tien Chang, Yu-Fen Lu, Chi-Wen Chang, Mark L Wahlqvist, Thomas Wetter, Chi-Ming Chu BMC Bioinformatics 2013, 14:100 (19 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

Unsupervised Bayesian linear unmixing of gene expression microarrays

Cécile Bazot, Nicolas Dobigeon, Jean-Yves Tourneret, Aimee K Zaas, Geoffrey S Ginsburg, Alfred O Hero BMC Bioinformatics 2013, 14:99 (19 March 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access Highly Accessed

NightShift: NMR Shift Inference by General Hybrid Model Training - a Framework for NMR Chemical Shift Prediction

Anna Katharina Dehof, Simon Loew, Hans-Peter Lenhof, Andreas Hildebrandt BMC Bioinformatics 2013, 14:98 (16 March 2013)

Abstract | Provisional PDF | PubMed

Methodology article   Open Access

Estimate hidden dynamic profiles of siRNA effect on apoptosis

Takanori Ueda, Daisuke Tominaga, Noriko Araki, Tomohiro Yoshikawa BMC Bioinformatics 2013, 14:97 (15 March 2013)

Abstract | Provisional PDF | PubMed

Methodology article   Open Access Highly Accessed

Mining for class-specific motifs in protein sequence classification

Satish M Srinivasan, Suleyman Vural, Brian R King, Chittibabu Guda BMC Bioinformatics 2013, 14:96 (15 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Software   Open Access

CGAP: a new comprehensive platform for the comparative analysis of chloroplast genomes

Jinkui Cheng, Xu Zeng, Guomin Ren, Zhihua Liu BMC Bioinformatics 2013, 14:95 (14 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Methodology article   Open Access Highly Accessed

An inferential framework for biological network hypothesis tests

Phillip D Yates, Nitai D Mukhopadhyay BMC Bioinformatics 2013, 14:94 (14 March 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

A distance-field based automatic neuron tracing method

Jinzhu Yang, Paloma T Gonzalez-Bellido, Hanchuan Peng BMC Bioinformatics 2013, 14:93 (12 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Methodology article   Open Access Highly Accessed

Inferring microRNA and transcription factor regulatory networks in heterogeneous data

Thuc D Le, Lin Liu, Bing Liu, Anna Tsykin, Gregory J Goodall, Kenji Satou, Jiuyong Li BMC Bioinformatics 2013, 14:92 (11 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access Highly Accessed

A comparison of methods for differential expression analysis of RNA-seq data

Charlotte Soneson, Mauro Delorenzi BMC Bioinformatics 2013, 14:91 (9 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Methodology article   Open Access Highly Accessed

An improved sequence based prediction protocol for DNA-binding proteins using SVM and comprehensive feature analysis

Chuanxin Zou, Jiayu Gong, Honglin Li BMC Bioinformatics 2013, 14:90 (9 March 2013)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Digital sorting of complex tissues for cell type-specific gene expression profiles

Yi Zhong, Ying-Wooi Wan, Kaifang Pang, Lionel ML Chow, Zhandong Liu BMC Bioinformatics 2013, 14:89 (7 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Methodology article   Open Access Highly Accessed

DNdisorder: predicting protein disorder using boosting and deep networks

Jesse Eickholt, Jianlin Cheng BMC Bioinformatics 2013, 14:88 (6 March 2013)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

Empirical Bayes estimation of posterior probabilities of enrichment: A comparative study of five estimators of the local false discovery rate

Zhenyu Yang, Zuojing Li, David R Bickel BMC Bioinformatics 2013, 14:87 (6 March 2013)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

Age-adjusted nonparametric detection of differential DNA methylation with case–control designs

Hanwen Huang, Zhongxue Chen, Xudong Huang BMC Bioinformatics 2013, 14:86 (6 March 2013)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

Make the most of your samples: Bayes factor estimators for high-dimensional models of sequence evolution

Guy Baele, Philippe Lemey, Stijn Vansteelandt BMC Bioinformatics 2013, 14:85 (6 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Research article   Open Access

Bivariate segmentation of SNP-array data for allele-specific copy number analysis in tumour samples

David Mosén-Ansorena, Ana María Aransay BMC Bioinformatics 2013, 14:84 (5 March 2013)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access

HuntMi: an efficient and taxon-specific approach in pre-miRNA identification

Adam Gudy¿, Micha¿ Wojciech Szcze¿niak, Marek Sikora, Izabela Makalowska BMC Bioinformatics 2013, 14:83 (5 March 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access

Learning a peptide-protein binding affinity predictor with kernel ridge regression

Sébastien Giguère, Mario Marchand, François Laviolette, Alexandre Drouin, Jacques Corbeil BMC Bioinformatics 2013, 14:82 (5 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Methodology article   Open Access

Prediction of heterogeneous differential genes by detecting outliers to a Gaussian tight cluster

Zihua Yang, Zhengrong Yang BMC Bioinformatics 2013, 14:81 (5 March 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access Highly Accessed

Comparative analysis of microbiome measurement platforms using latent variable structural equation modeling

Xiao Wu, Kathryn Berkow, Daniel N Frank, Ellen Li, Ajay S Gulati, Wei Zhu BMC Bioinformatics 2013, 14:79 (5 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Software   Open Access Highly Accessed

AUREA: an open-source software system for accurate and user-friendly identification of relative expression molecular signatures

John C Earls, James A Eddy, Cory C Funk, Younhee Ko, Andrew T Magis, Nathan D Price BMC Bioinformatics 2013, 14:78 (5 March 2013)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

GenePainter: a fast tool for aligning gene structures of eukaryotic protein families, visualizing the alignments and mapping gene structures onto protein structures

Björn Hammesfahr, Florian Odronitz, Stefanie Mühlhausen, Stephan Waack, Martin Kollmar BMC Bioinformatics 2013, 14:77 (4 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Software   Open Access Highly Accessed

BioTile, A Perl based tool for the identification of differentially enriched regions in tiling microarray data

Jerry Guintivano, Michal Arad, Kellie LK Tamashiro, Todd D Gould, Zachary A Kaminsky BMC Bioinformatics 2013, 14:76 (3 March 2013)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

virtualArray: a R/bioconductor package to merge raw data from different microarray platforms

Andreas Heider, Rüdiger Alt BMC Bioinformatics 2013, 14:75 (2 March 2013)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

MethylPCA: a toolkit to control for confounders in methylome-wide association studies

Wenan Chen, Guimin Gao, Srilaxmi Nerella, Christina M Hultman, Patrik KE Magnusson, Patrick F Sullivan, Karolina A Aberg, Edwin JCG van den Oord BMC Bioinformatics 2013, 14:74 (2 March 2013)

Abstract | Full text | PDF | PubMed

Software   Open Access

search GenBank: interactive orchestration and ad-hoc choreography of Web services in the exploration of the biomedical resources of the National Center For Biotechnology Information

Dariusz Mrozek, Bożena Małysiak-Mrozek, Artur Siążnik BMC Bioinformatics 2013, 14:73 (1 March 2013)

Abstract | Full text | PDF | PubMed


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