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Volume 10 (2009) - March 2009

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Methodology article   Open Access Highly Accessed

Cyndi: a multi-objective evolution algorithm based method for bioactive molecular conformational generation

Xiaofeng Liu, Fang Bai, Sisheng Ouyang, Xicheng Wang, Honglin Li, Hualiang Jiang BMC Bioinformatics 2009, 10:101 (31 March 2009)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Biological sequences as pictures – a generic two dimensional solution for iterated maps

Jonas S Almeida, Susana Vinga BMC Bioinformatics 2009, 10:100 (31 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access Highly Accessed

Markov clustering versus affinity propagation for the partitioning of protein interaction graphs

James Vlasblom, Shoshana J Wodak BMC Bioinformatics 2009, 10:99 (30 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access

Characterisation and correction of signal fluctuations in successive acquisitions of microarray images

Annie Glatigny, Hervé Delacroix, Thomas Tang, Nicolas François, Lawrence Aggerbeck, Marie-Hélène Mucchielli-Giorgi BMC Bioinformatics 2009, 10:98 (30 March 2009)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Modeling genomic data with type attributes, balancing stability and maintainability

Norbert Busch, Gero Wedemann BMC Bioinformatics 2009, 10:97 (27 March 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Identifying significant temporal variation in time course microarray data without replicates

Stephen C Billups, Margaret C Neville, Michael Rudolph, Weston Porter, Pepper Schedin BMC Bioinformatics 2009, 10:96 (26 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Software   Open Access Highly Accessed

JNets: Exploring networks by integrating annotation

Jamie I MacPherson, John W Pinney, David L Robertson BMC Bioinformatics 2009, 10:95 (26 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access Highly Accessed

Statistical and visual differentiation of subcellular imaging

Nicholas A Hamilton, Jack TH Wang, Markus C Kerr, Rohan D Teasdale BMC Bioinformatics 2009, 10:94 (22 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

New scoring schema for finding motifs in DNA Sequences

Fatemeh Zare-Mirakabad, Hayedeh Ahrabian, Mehdei Sadeghi, Abbas Nowzari-Dalini, Bahram Goliaei BMC Bioinformatics 2009, 10:93 (20 March 2009)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

MarVis: a tool for clustering and visualization of metabolic biomarkers

Alexander Kaever, Thomas Lingner, Kirstin Feussner, Cornelia Göbel, Ivo Feussner, Peter Meinicke BMC Bioinformatics 2009, 10:92 (20 March 2009)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Improved analysis of bacterial CGH data beyond the log-ratio paradigm

Lars Snipen, Otto L Nyquist, Margrete Solheim, Ågot Aakra, Ingolf F Nes BMC Bioinformatics 2009, 10:91 (19 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Bayesian clustering and feature selection for cancer tissue samples

Pekka Marttinen, Samuel Myllykangas, Jukka Corander BMC Bioinformatics 2009, 10:90 (18 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Database   Open Access Highly Accessed

The PHA Depolymerase Engineering Database: A systematic analysis tool for the diverse family of polyhydroxyalkanoate (PHA) depolymerases

Michael Knoll, Thomas M Hamm, Florian Wagner, Virginia Martinez, Jürgen Pleiss BMC Bioinformatics 2009, 10:89 (18 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Analyses of domains and domain fusions in human proto-oncogenes

Qi Liu, Jinling Huang, Huiqing Liu, Ping Wan, Xiuzi Ye, Ying Xu BMC Bioinformatics 2009, 10:88 (17 March 2009)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

Decon2LS: An open-source software package for automated processing and visualization of high resolution mass spectrometry data

Navdeep Jaitly, Anoop Mayampurath, Kyle Littlefield, Joshua N Adkins, Gordon A Anderson, Richard D Smith BMC Bioinformatics 2009, 10:87 (17 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

In silico prioritisation of candidate genes for prokaryotic gene function discovery: an application of phylogenetic profiles

Frank PY Lin, Enrico Coiera, Ruiting Lan, Vitali Sintchenko BMC Bioinformatics 2009, 10:86 (17 March 2009)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Statistical identification of gene association by CID in application of constructing ER regulatory network

Li-Yu D Liu, Chien-Yu Chen, Mei-Ju M Chen, Ming-Shian Tsai, Cho-Han S Lee, Tzu L Phang, Li-Yun Chang, Wen-Hung Kuo, Hsiao-Lin Hwa, Huang-Chun Lien, Shih-Ming Jung, Yi-Shing Lin, King-Jen Chang, Fon-Jou Hsieh BMC Bioinformatics 2009, 10:85 (17 March 2009)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Kerfdr: a semi-parametric kernel-based approach to local false discovery rate estimation

Mickael Guedj, Stephane Robin, Alain Celisse, Gregory Nuel BMC Bioinformatics 2009, 10:84 (16 March 2009)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

Automics: an integrated platform for NMR-based metabonomics spectral processing and data analysis

Tao Wang, Kang Shao, Qinying Chu, Yanfei Ren, Yiming Mu, Lijia Qu, Jie He, Changwen Jin, Bin Xia BMC Bioinformatics 2009, 10:83 (16 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

'Automics' is a new open-source software package for integrated spectral processing and analysis of nuclear magnetic resonance-based metabonomic datasets, which would otherwise require the use of several separate programs.

Research article   Open Access Highly Accessed

Finding evolutionarily conserved cis-regulatory modules with a universal set of motifs

Bartek Wilczynski, Norbert Dojer, Mateusz Patelak, Jerzy Tiuryn BMC Bioinformatics 2009, 10:82 (10 March 2009)

Abstract | Full text | PDF | PubMed

Software   Open Access Highly Accessed

GMFilter and SXTestPlate: software tools for improving the SNPlex™ genotyping system

Markus Teuber, Michael H Wenz, Stefan Schreiber, Andre Franke BMC Bioinformatics 2009, 10:81 (9 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access Highly Accessed

CNV-seq, a new method to detect copy number variation using high-throughput sequencing

Chao Xie, Martti T Tammi BMC Bioinformatics 2009, 10:80 (6 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

Adaptable data management for systems biology investigations

John Boyle, Hector Rovira, Chris Cavnor, David Burdick, Sarah Killcoyne, Ilya Shmulevich BMC Bioinformatics 2009, 10:79 (6 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access Highly Accessed

Performance of random forest when SNPs are in linkage disequilibrium

Yan A Meng, Yi Yu, L Adrienne Cupples, Lindsay A Farrer, Kathryn L Lunetta BMC Bioinformatics 2009, 10:78 (5 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access Highly Accessed

Development and evaluation of new mask protocols for gene expression profiling in humans and chimpanzees

Donna M Toleno, Gabriel Renaud, Tyra G Wolfsberg, Munirul Islam, Derek E Wildman, Kimberly D Siegmund, Joseph G Hacia BMC Bioinformatics 2009, 10:77 (5 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Methodology article   Open Access Highly Accessed

RNAslider: a faster engine for consecutive windows folding and its application to the analysis of genomic folding asymmetry

Yair Horesh, Ydo Wexler, Ilana Lebenthal, Michal Ziv-Ukelson, Ron Unger BMC Bioinformatics 2009, 10:76 (4 March 2009)

Abstract | Full text | PDF | PubMed

Methodology article   Open Access Highly Accessed

Edge detection in microscopy images using curvelets

Tobias Gebäck, Petros Koumoutsakos BMC Bioinformatics 2009, 10:75 (3 March 2009)

Abstract | Full text | PDF | PubMed | 1 comment

Software   Open Access Highly Accessed

RGG: A general GUI Framework for R scripts

Ilhami Visne, Erkan Dilaveroglu, Klemens Vierlinger, Martin Lauss, Ahmet Yildiz, Andreas Weinhaeusel, Christa Noehammer, Friedrich Leisch, Albert Kriegner BMC Bioinformatics 2009, 10:74 (2 March 2009)

Abstract | Full text | PDF | PubMed


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