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Editor-in-Chief Melissa Norton, MD
Section Editors
Biology Editor Penelope Webb, PhD
In-house Editor Maria Kowalczuk PhD
Welcome to BMC Bioinformatics published by BioMed Central
BMC Bioinformatics is an open access journal publishing original peer-reviewed research articles in all aspects of the development, testing and novel application of computational and statistical methods for the modeling and analysis of all kinds of biological data, as well as other areas of computational biology.
BMC Bioinformatics (ISSN 1471-2105) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, ACM, CABI, Thomson Reuters (ISI) and Google Scholar.
BMC Bioinformatics 2010, 11 :365
Protein-small molecule interactions can now be predicted with greater accuracy by a new algorithm on the web server IBIS that utilizes inference-by-homology to rank predicted binding sites based on their biological relevance.
BMC Bioinformatics 2010, 11 :358
Contextual data can now be integrated onto environmental sequence datasets through a web-based software tool, MetaBar, that barcodes samples and stores relevant data such as geographical location and sampling time in an online database.
BMC Bioinformatics 2010, 11 :266
Rapid and automated typing and subtyping of the influenza virus is now possible with a new algorithm 'FluTyper' designed to analyse MALDI mass spectra from proteolytic digests of the whole influenza virus and antigens.
BMC Bioinformatics 2010, 11 :240
Due to the ever increasing number of genomes reported, ENSEMBL has implemented an artificial intelligence pipeline
eHIVE
, based on a self-organizing workflow system, to provide updates to its comparative genomics resources.
BMC Bioinformatics 2010, 11 :207
Probe spot intensity bias on expression microarrays, caused by runs of three or more guanine residues, can be corrected using a newly generated positional and motif dependent sensitivity model
Volume 11 Suppl 4
Meeting abstracts
Cadiz, KY, USA. 19-21 March 2010
Volume 11 Suppl 3
Proceedings
Washington, DC, USA. 1-4 November 2009
Volume 11 Suppl 2
Proceedings
Hong Kong. 6 November 2009
more info ]
Research article
Automatic detection of anchor points for multiple sequence alignment Florian Pitschi, Claudine Devauchelle, Eduardo Corel BMC Bioinformatics 2010, 11 :445 (2 [Abstract ] [Provisional PDF ]
Software
Genome3D: a viewer-model framework for integrating and visualizing multi-scale epigenomic information within a three-dimensional genome Thomas M Asbury, Matt Mitman, Jijun Tang, W JIM Zheng BMC Bioinformatics 2010, 11 :444 (2 [Abstract ] [Provisional PDF ]
Methodology article
Efficient Bayesian approach for multilocus association mapping including gene-gene interactions Pekka Marttinen, Jukka Corander BMC Bioinformatics 2010, 11 :443 (2 [Abstract ] [Provisional PDF ]
Methodology article
Forward-time simulation of realistic samples for genome-wide association studies Bo Peng, Christopher I Amos BMC Bioinformatics 2010, 11 :442 (1 [Abstract ] [Provisional PDF ]
Methodology article
Relations as patterns: bridging the gap between OBO and
OWL
Robert Hoehndorf, Anika Oellrich, Michel Dumontier, Janet Kelso, Dietrich Rebholz-Schuhmann, Heinrich Herre BMC Bioinformatics 2010, 11 :441 (31 [Abstract ] [Provisional PDF ]
Methodology article
An exploratory data analysis method to reveal modular latent structures in high-throughput data Tianwei Yu BMC Bioinformatics 2010, 11 :440 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site annotation Gong-Hua Li, Jing-Fei Huang BMC Bioinformatics 2010, 11 :439 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
*omeSOM: a software for clustering and visualization of transcriptional and metabolite data mined from interspecific crosses of crop plants. Diego H Milone, Georgina S Stegmayer, Laura Kamenetzky, Mariana Lopez, Je Min Lee, James J Giovannoni, Fernando Carrari BMC Bioinformatics 2010, 11 :438 (26 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Coherent pipeline for biomarker discovery using mass spectrometry and bioinformatics Ali Al-Shahib, Raju Misra, Nadia Ahmod, Min Fang, Haroun Shah, Saheer Gharbia BMC Bioinformatics 2010, 11 :437 (26 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
A Dynamic Noise Level Algorithm for Spectral Screening of Peptide MS/MS Spectra Hua Xu, Michael A Freitas BMC Bioinformatics 2010, 11 :436 (23 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Identification of tumor-associated cassette exons in human cancer through EST-based computational prediction and experimental validation Alessio Valletti, Anna Anselmo, Marina Mangiulli, Ilenia Boria, Flavio Mignone, Giuseppe Merla, Vincenzo D'Angelo, Apollonia Tullo, Elisabetta Sbisa', Anna Maria D'Erchia, Graziano Pesole Molecular Cancer 2010, 9 :230 (2 [Abstract ] [Provisional PDF ]
Editorial
A call for BMC Research Notes contributions promoting best practice in data standardization, sharing and publication Iain Hrynaszkiewicz BMC Research Notes 2010, 3 :235 (2 [Abstract ] [Provisional PDF ]
Research article
Benefits of biomarker selection and clinico-pathological covariate inclusion in breast cancer prognostic models Fabio Parisi, Ana M Gonzalez, Yasmine Nadler, Robert L Camp, David L Rimm, Harriet M Kluger, Yuval Kluger Breast Cancer Research 2010, 12 :R66 (1 [Abstract ] [Provisional PDF ]
Methodology article
Gene set analysis exploiting the topology of a pathway Maria Sofia Massa, Monica Chiogna, Chiara Romualdi BMC Systems Biology 2010, 4 :121 (1 [Abstract ] [Provisional PDF ]
Research article
Bayesian random local clocks, or one rate to rule them all Alexei J Drummond, Marc A Suchard BMC Biology 2010, 8 :114 (31 [Abstract ] [Provisional PDF ]
Research article
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis Carola Huthmacher, Andreas Hoppe, Sascha Bulik, Hermann-Georg Holzhutter BMC Systems Biology 2010, 4 :120 (31 [Abstract ] [Provisional PDF ]
Method
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites Doron Betel, Anjali Koppal, Phaedra Agius, Chris Sander, Christina Leslie Genome Biology 2010, 11 :R90 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
Mapping Haplotype-haplotype Interactions with Adaptive LASSO Ming Li, Roberto Romero, Wenjiang J Fu, Yuehua Cui BMC Genetics 2010, 11 :79 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Genes and pathways for CO2 fixation in the obligate, chemolithoautotrophic acidophile, Acidithiobacillus ferrooxidans Mario Esparza, Juan Pablo Cardenas, Botho Bowien, Eugenia Jedlicki, David S. Holmes BMC Microbiology 2010, 10 :229 (27 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Method
A standard variation file format for human genome sequences Martin G Reese, Barry Moore, Colin Batchelor, Fidel Salas, Fiona Cunningham, Gabor Marth, Lincoln Stein, Paul Flicek, Mark Yandell, Karen Eilbeck Genome Biology 2010, 11 :R88 (26 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Featured articles
eHIVE
, based on a self-organizing workflow system, to provide updates to its comparative genomics resources. 
