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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Tim Sands PhD
Welcome to BMC Bioinformatics published by BioMed Central
BMC Bioinformatics is an open access journal publishing original peer-reviewed research articles in all aspects of the development, testing and novel application of computational and statistical methods for the modeling and analysis of all kinds of biological data, as well as other areas of computational biology.
BMC Bioinformatics (ISSN 1471-2105) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
BMC Bioinformatics 2009, 10 :350
Methods for quantifying cell
cell contact often rely on global descriptors, such as overall cell density, but a new statistical model that accounts for local interactions, such as individual cell-cell distances, reduces noisy data and effectively describes contact inhibition effects.
BMC Bioinformatics 2009, 10 :342
IQuantitator is a sophisticated and novel software package, which uses a statistical inference approach to integrate multiple iTRAQ experiments, allowing users to estimate changes in protein expression levels under various treatment conditions
BMC Bioinformatics 2009, 10 :334
Magellanes is a discovery engine that searches the web for bioinformatics services and organizes them into workflows using a semantic approach.
BMC Bioinformatics 2009, 10 :324
KEGGconverter offers users a single workflow software which merges selected KGML pathway files into a fully functional metabolic network SBML model, enhanced with default kinetics, and ready for simulation purposes.
BMC Bioinformatics 2009, 10 :316
A binning method that doesn't rely on previously known sequences accurately clusters short environmental shotgun sequences by taxonomic origin in low complexity communities, based on their k-mer distributions.
Volume 10 Suppl 13
Meeting abstracts
Stockholm, Sweden. 27 June 2009
Volume 10 Suppl 12
Research
Varenna, Italy. 19 Volume 10 Suppl 11
Proceedings
Starkville, MS, USA. 20
more info ]
Research article
Elucidation of functional consequences of signalling pathway interactions Adaoha E C Ihekwaba, Phuong T Nguyen, Corrado Priami BMC Bioinformatics 2009, 10 :370 (6 [Abstract ] [Provisional PDF ]
Research article
RNA folding on the 3D triangular lattice Joel Gillespie, Martin Mayne, Minghui Jiang BMC Bioinformatics 2009, 10 :369 (5 [Abstract ] [Provisional PDF ]
Database
A biosegmentation benchmark for evaluation of bioimage analysis methods Elisa Drelie Gelasca, Boguslaw Obara, Dmitry Fedorov, Kristian Kvilekval, B. S. Manjunath BMC Bioinformatics 2009, 10 :368 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Database
GLIDERS - A web-based search engine for genome-wide linkage disequilibrium between HapMap SNPs Robert Lawrence, Aaron G Day-Williams, Richard Mott, John Broxholme, Lon R Cardon, Eleftheria Zeggini BMC Bioinformatics 2009, 10 :367 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Methodology article
(PS)2-v2: template-based protein structure prediction server Chih-Chieh Chen, Jenn-Kang Hwang, Jinn-Moon Yang BMC Bioinformatics 2009, 10 :366 (31 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Prediction of hot spot residues at protein-protein interfaces by combining machine learning and energy-based methods Stefano Lise, Cedric Archambeau, Massimiliano Pontil, David T Jones BMC Bioinformatics 2009, 10 :365 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
multiplierz: an extensible API based desktop environment for proteomics data analysis Jignesh R Parikh, Manor Askenazi, Scott B Ficarro, Tanya Cashorali, James T Webber, Nathaniel C Blank, Yi Zhang, Jarrod A Marto BMC Bioinformatics 2009, 10 :364 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
A novel R-package graphic user interface for the analysis of metabonomic profiles Jose L Izquierdo-Garcia, Ignacio Rodriguez, Angelos Kyriazis, Palmira Villa, Pilar Barreiro, Manuel Desco, Jesus Ruiz-Cabello BMC Bioinformatics 2009, 10 :363 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
BARCRAWL and BARTAB: Software tools for the design and implementation of barcoded primers for highly multiplexed DNA sequencing Daniel N Frank BMC Bioinformatics 2009, 10 :362 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Predicting sulfotyrosine sites using the random forest algorithm with significantly improved prediction accuracy Zheng Rong Yang BMC Bioinformatics 2009, 10 :361 (29 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Evolution of genomic sequence inhomogeneity at mid-range scales Ashwin Prakash, Samuel S. Shepard, Jie He, Benjamin Hart, Miao Chen, Surya P. Amarachintha, Olga Mileyeva-Biebesheimer, Jason M. Bechtel, Alexei Fedorov BMC Genomics 2009, 10 :513 (5 [Abstract ] [Provisional PDF ]
Methodology article
Using the ratio of means as the effect size measure in combining results of microarray experiments Pingzhao Hu, Celia MT Greenwood, Joseph Beyene BMC Systems Biology 2009, 3 :106 (5 [Abstract ] [Provisional PDF ]
Research article
STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect Sean P Pitroda, Bassam T Wakim, Ravi F Sood, Mara G Beveridge, Michael A Beckett, Dhara M MacDermed, Ralph R Weichselbaum, Nikolai N Khodarev BMC Medicine 2009, 7 :68 (5 [Abstract ] [Provisional PDF ]
Methodology article
Information-theoretic gene-gene and gene-environment interaction analysis of quantitative traits Pritam Chanda, Lara Sucheston, Song Liu, Aidong Zhang, Murali Ramanathan BMC Genomics 2009, 10 :509 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Computational prediction of splicing regulatory elements shared by Tetrapoda organisms Alexander Churbanov, Igor Vorechovsky, Chindo Hicks BMC Genomics 2009, 10 :508 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy Wei Shao, Mary Kearney, Frank Maldarelli, John W Mellors, Robert M Stephens, Jeffrey D Lifson, Vineet N KewalRamani, Zandrea Ambrose, John M Coffin, Sarah E Palmer Retrovirology 2009, 6 :101 (4 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Predicting prognosis in hepatocellular carcinoma after curative surgery with common clinicopathologic parameters Ke Hao, John M Luk, Nikki P Y Lee, Mao Mao, Chunsheng Zhang, Mark D Ferguson, John Lamb, Hongyue Dai, Irene O Ng, Pak C Sham, Ronnie T P Poon BMC Cancer 2009, 9 :389 (3 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Network dynamics of eukaryotic LTR retroelements beyond phylogenetic trees Carlos Llorens, Alfonso Munoz-Pomer, Lucia Bernad, Hector Botella, Andres Moya Biology Direct 2009, 4 :41 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Divergence of exonic splicing elements after gene duplication and the impact on gene structures Zhenguo Zhang, Li Zhou, Ping Wang, Yang Liu, Xianfeng Chen, Landian Hu, Xiangyin Kong Genome Biology 2009, 10 :R120 (2 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Accurate molecular classification of cancer using simple rules Xiaosheng Wang, Osamu Gotoh BMC Medical Genomics 2009, 2 :64 (30 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Featured articles
cell contact
