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BMC Genomics

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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Matthew Kaiser PhD


Welcome to BMC Genomics published by BioMed Central
BMC Genomics is an open access journal publishing original peer-reviewed research articles in all aspects of genome-scale analysis, functional genomics, and proteomics. BMC Genomics (ISSN 1471-2164) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, EMBASE, Scopus, Zoological Record, Thomson Reuters (ISI) and Google Scholar.



BMC  Featured articles   

Credit Eric Engbretson - US Fish and Wildlife Service
BMC Genomics 2009, 10:546
Phylogenetically conserved expression patterns in spermatogenesis and testis-specific genes of the male rainbow trout are shown by transcriptome analysis, identifying new pathways involved during spermatogonia self-renewal, meiosis and gamete differentiation.
BMC Genomics 2009, 10:545
Heregulin and EGF bind the same receptor and induce similar early responses in breast cancer cells, but a later sequence of transcription factors induced only by heregulin, including FosL1 and FHL2, suppresses ERK signaling to give differentiation rather than proliferation
Wikipedia
BMC Genomics 2009, 10:539
Comparative analysis of the polyploid genomes of Brassica rapa and Arabidopsis thaliana reveals many unanticipated collinearity blocks and frequent segmental inversions, shedding new light on genome evolution within the Brassicaceae.
Image credit: Wikipedia
BMC Genomics 2009, 10:525
Among 2,200 expressed genes identified in the fungivorus nematode Aphelenchus avenae, there are a set of genes encode cell-wall-degrading enzymes, indicating that this nematode also feeds on plants, and supporting the idea that plant parasitism has evolved from fungal feeding.
BMC Genomics 2009, 10:499
The antiproliferative effects of vitamin D on a breast tumour cell line persist despite knockdown of the vitamin D receptor gene, and variants resistant to these anti-proliferative effects do not show changes in known vitamin D signaling pathway genes.


BMC  Latest supplements published in BMC Genomics


Volume 10 Suppl 2
Proceedings
Starkville, MS, USA. 1922 May 2008

Volume 10 Suppl 1
Research
Las Vegas, NV, USA. 1417 July 2008





BMC  Latest articles published in BMC Genomics        [more info]


Research article
Novel motifs distinguish multiple homologues of Polycomb in vertebrates: expansion and diversification of the epigenetic toolkit
Ramamoorthy Senthilkumar, Rakesh K Mishra
BMC Genomics 2009, 10:549 (20November2009)
[Abstract] [Provisional PDF]

Research article
Characterisation of microRNA expression in post-natal mouse mammary gland development
Stefanie Avril-Sassen, Leonard D Goldstein, John Stingl, Cherie Blenkiron, John Le Quesne, Inmaculada Spiteri, Konstantina Karagavriilidou, Christine J Watson, Simon Tavare, Eric A Miska, Carlos Caldas
BMC Genomics 2009, 10:548 (20November2009)
[Abstract] [Provisional PDF]

Methodology article
De novo 454 sequencing of barcoded BAC pools for comprehensive gene survey and genome analysis in the complex genome of barley
Burkhard Steuernagel, Stefan Taudien, Heidrun Gundlach, Michael Seidel, Ruvini Ariyadasa, Daniela Schulte, Andreas Petzold, Marius Felder, Andreas Graner, Uwe Scholz, Klaus FX Mayer, Matthias Platzer, Nils Stein
BMC Genomics 2009, 10:547 (20November2009)
[Abstract] [Provisional PDF]

Research article
Expression profiling of rainbow trout testis development identifies evolutionary conserved genes involved in spermatogenesis
Antoine D Rolland, Jean-Jacques Lareyre, Anne-Sophie Goupil, Jerome Monfort, Marie-Jose Ricordel, Diane Esquerre, Karine Hugot, Remi Houlgatte, Frederic Chalmel, Florence F Le Gac
BMC Genomics 2009, 10:546 (20November2009)
[Abstract] [Provisional PDF]

Research article
Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells
Yuko Saeki, Takaho Endo, Kaori Ide, Takeshi Nagashima, Noriko Yumoto, Tetsuro Toyoda, Harukazu Suzuki, Yoshihide Hayashizaki, Yoshiyuki Sakaki, Mariko Okada-Hatakeyama
BMC Genomics 2009, 10:545 (20November2009)
[Abstract] [Provisional PDF]

Research article
Differentially expressed genes for aggressive pecking behaviour in laying hens
Bart Buitenhuis, Jakob Hedgaard, Luc Janss, Peter Sorensen
BMC Genomics 2009, 10:544 (19November2009)
[Abstract] [Provisional PDF]

Research article
A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells
Raffaella Calligaris, Cristina Bellarosa, Rossana Foti, Paola Roncaglia, Pablo Giraudi, Helena Krmac, Claudio Tiribelli, Stefano Gustincich
BMC Genomics 2009, 10:543 (19November2009)
[Abstract] [Provisional PDF]

Research article
Gene network and pathway analysis of bovine mammary tissue challenged with Streptococcus uberis reveals induction of cell proliferation and inhibition of PPAR-gamma signaling as potential mechanism for the negative relationships between immune response and lipid metabolism
Kasey M Moyes, James K Drackley, Dawn E Morin, Massimo Bionaz, Sandra L Rodriguez-Zas, Robin E Everts, Harris A Lewin, Juan J Loor
BMC Genomics 2009, 10:542 (19November2009)
[Abstract] [Provisional PDF]

Correction
Correction: Digital PCR provides sensitive and absolute calibration for high throughput sequencing
Richard A White III, Paul C Blainey, H Christina Fan, Stephen R Quake
BMC Genomics 2009, 10:541 (19November2009)
[Abstract] [Provisional PDF]

Research article
Comparative transcripts profiling reveals new insight into molecular processes regulating lycopene accumulation in a sweet orange (Citrus sinensis) red-flesh mutant
Qiang Xu, Keqin Yu, Andan Zhu, Junli Ye, Qing Liu, Jianchen Zhang, Xiuxin Deng
BMC Genomics 2009, 10:540 (18November2009)
[Abstract] [Provisional PDF]


BMC  Latest relevant articles from other journals in BioMed Central


Research
In plants, expression breadth and expression level distinctly and non-linearly correlate with gene structure
Hongxing Yang
Biology Direct 2009, 4:45 (21November2009)
[Abstract] [Provisional PDF]

Software
Searching for SNPs with cloud computing
Ben Langmead, Michael C Schatz, Jimmy Lin, Mihai Pop, Steven L Salzberg
Genome Biology 2009, 10:R134 (20November2009)
[Abstract] [Provisional PDF]

Method
COMIT: Identification of noncoding motifs under selection in coding sequences
Deniz Kural, Yang Ding, Jiantao Wu, Alicia Korpi, Jeffrey H Chuang
Genome Biology 2009, 10:R133 (20November2009)
[Abstract] [Provisional PDF]

Research article
Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces
Imke E Mulder, Bettina Schmidt, Christopher R Stokes, Marie Lewis, Mick Bailey, Rustam I Aminov, James I Prosser, Bhupinder P Gill, John R Pluske, Claus-Dieter Mayer, Corran Musk, Denise Kelly
BMC Biology 2009, 7:79 (20November2009)
[Abstract] [Provisional PDF]

Methodology
HAMSTER: visualizing microarray experiments as a set of minimum spanning trees
Raymond Wan, Larisa Kiseleva, Hajime Harada, Hiroshi Mamitsuka, Paul Horton
Source Code for Biology and Medicine 2009, 4:8 (20November2009)
[Abstract] [Provisional PDF]

Research article
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states
Aaron L Sarver, Amy J French, Pedro M Borralho, Venugopal Thayanithy, Ann L Oberg, Kevin AT Silverstein, Bruce W Morlan, Shaun M Riska, Lisa A Boardman, Julie M Cunningham, Subbaya Subramanian, Liang Wang, Tom C Smyrk, Cecilia MP Rodrigues, Stephen N Thibodeau, Clifford J Steer
BMC Cancer 2009, 9:401 (18November2009)
[Abstract] [Provisional PDF]

Research
CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features
Kobby Essien, Sebastien Vigneau, Sofia Apreleva, Larry N Singh, Marisa S Bartolomei, Sridhar Hannenhalli
Genome Biology 2009, 10:R131 (18November2009)
[Abstract] [Provisional PDF]

Research article
Genomic and phenotypic variation in epidemic-spanning Salmonella enterica serovar Enteritidis isolates
Laura Betancor, Lucia Yim, Maria Fookes, Araci Martinez, Nicholas R. Thomson, Alasdair Ivens, Sarah Peters, Clare Bryant, Gabriela Algorta, Samuel Kariuki, Felipe Schelotto, Duncan Maskell, Gordon Dougan, Jose A. Chabalgoity
BMC Microbiology 2009, 9:237 (18November2009)
[Abstract] [Provisional PDF]

Methodology article
The ontology of biological sequences
Robert Hoehndorf, Janet Kelso, Heinrich Herre
BMC Bioinformatics 2009, 10:377 (18November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Genome scale transcriptome analysis of shoot organogenesis in Populus
Yanghuan Bao, Palitha Dharmawardhana, Todd C. Mockler, Steven H. Strauss
BMC Plant Biology 2009, 9:132 (17November2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

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