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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Erik Alexandersson


Welcome to BMC Genomics published by BioMed Central
BMC Genomics is an open access journal publishing original peer-reviewed research articles in all aspects of gene mapping, sequencing and analysis, functional genomics, and proteomics. BMC Genomics (ISSN 1471-2164) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Zoological Record, Thomson Reuters (ISI) and Google Scholar.



BMC  Featured articles   

Gram negative bacterium image in Wikipedia english edition
BMC Genomics 2008, 9:427
The genome sequence of the bacterium Aeromonas salmonicida and the comparison of it to Aeromonas hydrophila yields new insights into the evolution and virulence factors that cause furunculusis, a bacterial septicaemia, in salmonid fish.
Image credit: Jim Gathany, CDC (public domain)
BMC Genomics 2008, 9:425
Comparative genomics of small RNA regulatory components - miRNA, siRNA and piRNA - in the three important mosquito vectors reveals novel motifs indicating that a variety of transcription control mechanisms operate in mosquito anti-viral defense pathways.
BMC Genomics 2008, 9:408
A combination of microarrays, RNA interference and comparative genomics uncovered direct regulatory targets of Sox10, a transcription factor implicated in the development of several important cell lineages, including the peripheral glia.
Ixodes image from Wikipedia English edition
BMC Genomics 2008, 9:372
Subolesin is a conserved protein recently found in Ixodes scapularis that plays a role in tick blood digestion, reproduction and development, and is now implicated in the modulation of genes involved in multiple cellular pathways.
Image: Rogic et al.
BMC Genomics 2008, 9:355
The splicing efficiency of an S. cerevisiae ribosomal protein intron is shown by modeling to be tightly controlled by structural branchpoint distances, highlighting the importance of pre-mRNA secondary structure in splicing.


BMC  Latest supplements published in BMC Genomics


Volume 9 Suppl 2
Research
Boston, MA, USA. 1417 October 2007





BMC  Latest articles published in BMC Genomics        [more info]


Research article
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones
Sacha J Pidot, Hui Hong, Torsten Seemann, Jessica L Porter, Marcus J Yip, Artem Men, Matthew Johnson, Peter Wilson, John K Davies, Peter F Leadlay, Timothy P Stinear
BMC Genomics 2008, 9:462 (7October2008)
[Abstract] [Provisional PDF]

Database
DroID: the Drosophila Interactions Database, a comprehensive resource for annotated gene and protein interactions
Jingkai Yu, Svetlana Pacifico, Guozhen Liu, Russell L. Finley Jr.
BMC Genomics 2008, 9:461 (7October2008)
[Abstract] [Provisional PDF]

Methodology article
Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals
Ruben van Boxtel, Pim W Toonen, Mark Verheul, Henk S van Roekel, Isaac J Nijman, Victor Guryev, Edwin Cuppen
BMC Genomics 2008, 9:460 (7October2008)
[Abstract] [Provisional PDF]

Methodology article
A MITE-based genotyping method to reveal hundreds of DNA polymorphisms in an animal genome after a few generations of artificial selection
Aurelie Bonin, Margot Paris, Laurence Despres, Guillaume Tetreau, Jean-Philippe David, Andrzej Kilian
BMC Genomics 2008, 9:459 (6October2008)
[Abstract] [Provisional PDF]

Research article
Adrenaline modulates the global transcriptional profile of Salmonella revealing a role in the antimicrobial peptide and oxidative stress resistance responses
Michail H Karavolos, Hannah Spencer, David M Bulmer, Arthur Thompson, Klaus Winzer, Paul Williams, Jay C D Hinton, C m ANJAM Khan
BMC Genomics 2008, 9:458 (6October2008)
[Abstract] [Provisional PDF]

Database
CoGemiR: a comparative genomics microRNA database
Vincenza Maselli, Diego Di Bernardo, Sandro Banfi
BMC Genomics 2008, 9:457 (6October2008)
[Abstract] [Provisional PDF]

Research article
Promoter-sharing by different genes in human genome-- CPNE1 and RBM12 gene pair as an example
Wanling Yang, Ping Ng, Minghui Zhao, Thomas K.F. Wong, Siu-Ming Yiu, Yu Lung Lau
BMC Genomics 2008, 9:456 (3October2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Unassigned MURF1 of kinetoplastids codes for NADH dehydrogenase subunit 2
Sivakumar Kannan, Gertraud Burger
BMC Genomics 2008, 9:455 (2October2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Selection and mutation on microRNA target sequences during rice evolution
Xingyi Guo, Yijie Gui, Yu Wang, Qian-Hao Zhu, Chris Helliwell, Longjiang Fan
BMC Genomics 2008, 9:454 (2October2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Splice-mediated Variants of Proteins (SpliVaP) - data and characterization of changes in signatures among protein isoforms due to alternative splicing.
Matteo Floris, Massimiliano Orsini, Thangavel ALPHONSE Thanaraj
BMC Genomics 2008, 9:453 (2October2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]


BMC  Latest relevant articles from other journals in BioMed Central


Software
XplorSeq: A software environment for integrated management and phylogenetic analysis of metagenomic sequence data
Daniel N Frank
BMC Bioinformatics 2008, 9:420 (7October2008)
[Abstract] [Provisional PDF]

Database
A database of phylogenetically atypical genes in archaeal and bacterial genomes, identified using the DarkHorse algorithm
Sheila Podell, Terry Gaasterland, Eric E Allen
BMC Bioinformatics 2008, 9:419 (7October2008)
[Abstract] [Provisional PDF]

Methodology article
Patterns of evolutionary constraints on genes in humans
Subhajyoti De, Nuria Lopez-Bigas, Sarah A Teichmann
BMC Evolutionary Biology 2008, 8:275 (7October2008)
[Abstract] [Provisional PDF]

Research article
High-resolution array CGH clarifies events occurring on 8p in carcinogenesis
Susanna L Cooke, Jessica CM Pole, Suet-Feung Chin, Ian O Ellis, Carlos Caldas, Paul AW Edwards
BMC Cancer 2008, 8:288 (7October2008)
[Abstract] [Provisional PDF]

Research article
The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae
Darren J Obbard, Deborah M Callister, Francis M Jiggins, Dinesh C Soares, Guiyan Yan, Tom J Little
BMC Evolutionary Biology 2008, 8:274 (7October2008)
[Abstract] [Provisional PDF]

Research article
The Caenorhabditis chemoreceptor gene families
James H Thomas, Hugh M Robertson
BMC Biology 2008, 6:42 (6October2008)
[Abstract] [Provisional PDF]

Methodology article
A Method for Analyzing Censored Survival Phenotype with Gene Expression Data
Tong Tong Wu, Wei Sun, Shinsheng Yuan, Chun-Houh Chen, Ker-Chau Li
BMC Bioinformatics 2008, 9:417 (6October2008)
[Abstract] [Provisional PDF]

Research article
The Role of Positive Selection in Determining the Molecular Cause of Species Differences in Disease
Jessica J Vamathevan, Samiul Hasan, Richard D Emes, Heather Amrine-Madsen, Dilip Rajagopalan, Simon D Topp, Vinod D Kumar, Mike Word, Mark D Simmons, Steven M Foord, Philippe Sanseau, Ziheng Yang, Joanna D Holbrook
BMC Evolutionary Biology 2008, 8:273 (6October2008)
[Abstract] [Provisional PDF]

Software
BATS: a Bayesian user-friendly software for Analyzing Time Series microarray experiments
Claudia Angelini, Luisa Cutillo, Daniela De Canditiis, Margherita Mutarelli, Marianna Pensky
BMC Bioinformatics 2008, 9:415 (6October2008)
[Abstract] [Provisional PDF]

Research article
Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach
Firoz Anwar, Syed Murtuza Baker, Taskeed Jabid, Md. Mehedi Hasan, Mohammad Shoyaib, Haseena Khan, Ray Walshe
BMC Bioinformatics 2008, 9:414 (4October2008)
[Abstract] [Provisional PDF]

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