Prions
Edited by:
Prof Alun Williams
Prions are infectious agents that are responsible for a number of neurodegenerative diseases, known as Transmissible Spongiform Encephalopathies (TSEs), including Bovine Spongiform Encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in humans. Prion diseases can be genetic, infectious, or sporadic, and they all involve modification of the prion protein (PrP). Here we present a compilation of manuscripts on various aspects of TSEs and their causative agents.
Collection published: 6 July 2009
Last updated: 18 November 2010
|
|
|
Association analysis of PRNP gene region with chronic wasting disease in Rocky Mountain elk
Stephen N White, Terry R Spraker, James O Reynolds, Katherine I O'Rourke BMC Research Notes 2010, 3:314 (18 November 2010)
Abstract | Full text | PDF
| PubMed
|
|
|
|
Effect of autolysis on the specificity of bovine spongiform encephalopathy rapid tests
Daniela Meloni, Katia Varello, Marzia Pezzolato, Elsa Manzardo, Maria C Cavarretta, Francesco Ingravalle, Maria Caramelli, Elena Bozzetta BMC Research Notes 2010, 3:193 (14 July 2010)
Abstract | Full text | PDF
| PubMed
|
|
|
|
Two adjacent nuclear factor-binding domains activate expression from the human PRNP promoter
Michael J Taheny, Nerik Izkhakov, Alexander A Vostrov, Wolfgang W Quitschke BMC Research Notes 2009, 2:178 (9 September 2009)
Abstract | Full text | PDF
| PubMed | Cited on BioMed Central
|
Editor’s summary
Analysis of the human prion protein promoter revealed two binding sites for as yet unidentified nuclear factors that activate expression of the promoter and could serve as therapeutic targets for transmissible spongiform encephalopathies.
|
|
|
|
Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivity
Christopher J Johnson, PUPA Gilbert, Debbie McKenzie, Joel A Pedersen, Judd M Aiken BMC Research Notes 2009, 2:121 (6 July 2009)
Abstract | Full text | PDF
| PubMed
|
|
|
|
Ablation of prion protein immunoreactivity by heating in saturated calcium hydroxide
Justin J Greenlee, Eric M Nicholson, Amir N Hamir, Gary P Noyes, Mark T Holtzapple, Marcus E Kehrli BMC Research Notes 2008, 1:99 (28 October 2008)
Abstract | Full text | PDF
| PubMed
|
|
|
|
A sequencing strategy for identifying variation throughout the prion gene of BSE-affected cattle
Michael L Clawson, Michael P Heaton, John W Keele, Timothy PL Smith, Gregory P Harhay, Juergen A Richt, William W Laegreid BMC Research Notes 2008, 1:32 (23 June 2008)
Abstract | Full text | PDF
| PubMed
|
