Welcome to BMC Research Notespublished by BioMed Central
BMC Research Notes is an open access journal publishing scientifically sound research across all fields of biology and medicine, enabling authors to publish updates to previous research, software tools and databases, data sets, small-scale clinical studies, and reports of confirmatory or 'negative' results. Additionally the journal welcomes descriptions of incremental improvements to methods as well as short correspondence items and hypotheses.
Submit your manuscript now via our online submission system. For more information about the journal, contact researchnotes@biomedcentral.com.
We are looking for enthusiastic researchers who would like to have an editorial involvement with BMC Research Notes.
A key objective of BMC Research Notes is to ensure that associated data files will, wherever possible, be published in standard, reusable formats and are exposed to ensure that they are searchable and easily harvested for reuse. We are working with researchers across the full spectrum of biomedical research to define appropriate recommendations for domain-specific data file standards, and we aim to provide detailed 'Additional data file' preparation guidelines, to complement our current detailed figure preparation guidelines.
BMC Research Notes provides a home for short publications, case series, incremental updates to previous work, results of individual experiments and similar material that currently lacks a suitable outlet. The intention is to reduce the loss suffered by the research community when such results remain unpublished. Submissions are fully peer-reviewed, and will be handled by an international board of academic Associate Editors spanning all biological and medical disciplines.
Analysis of the mitochondrial DNA of Radopholus similis, a parasitic nematode which ravages citrus, banana and ginger plantations, reveals several idiosyncrasies, including a unique evolution of the genetic code, the canonical Ochre (UAA) stop codon being translated as a tyrosine.
Analysis of the human prion protein promoter revealed two binding sites for as yet unidentified nuclear factors that activate expression of the promoter and could serve as therapeutic targets for transmissible spongiform encephalopathies.
The RNAi response is not affected by the absence of the fragile mental X retardation protein (FMRP) in fibroblasts from patients with fragile X syndrome, confirming previous data from mouse fibroblasts.
Brain imaging reveals a thickened brain cortex after regular playing of the videogame Tetris, while cortical activation observed during play decreases slightly with practice, in areas distinct from those showing maximum structural change.
Vincent Smith discusses the changing nature of data publication, the challenges that face the Open Science movement, and why the publication of primary scientific data is important to us all.
Latest articles published in BMC Research Notes [more info]