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Volume 11 (2011) - April 2011

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Research article   Open Access

Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakness

Chul Kim, Sapeckshita Srivastava, Marian Rice, Tanja A Godenschwege, Brooke Bentley, Saranya Ravi, Shuang Shao, Craig T Woodard, Lawrence M Schwartz BMC Physiology 2011, 11:7 (25 April 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Ectopic expression of human amyloid precursor protein (hAPP) in fruit flies leads to age- and activity-dependent behavioral defects but does not compromise muscle development or animal longevity.